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Sku: P101298-50 μl

Specification

Full name LRRC19 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
Swissprot No Q9H756
Gene Accession BC126156
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or LRRC19 antigen-treated (Neutralization experiment) using P101298(LRRC19 Antibody) at dilution 1/30
WB Positive control P101298-WB-1-P
WB Recommended dilution 42 kDa
IHC predicted cell location Predicted cell location: Cytoplasm or Nucleus
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 25-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P101298-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or LRRC19 antigen-treated (Neutralization experiment) using P101298(LRRC19 Antibody) at dilution 1/30

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