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Full name | LRRC19 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530. |
Swissprot No | Q9H756 |
Gene Accession | BC126156 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or LRRC19 antigen-treated (Neutralization experiment) using P101298(LRRC19 Antibody) at dilution 1/30 |
WB Positive control | P101298-WB-1-P |
WB Recommended dilution | 42 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm or Nucleus |
IHC positive control | Positive control: Human thyroid cancer |
IHC Recommed dilution | Recommended dilution: 25-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P101298-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or LRRC19 antigen-treated (Neutralization experiment) using P101298(LRRC19 Antibody) at dilution 1/30
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