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Sku: P111841-50 μl
Categories: Primary Antibodies

Specification

Full name HLA-DPA1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Swissprot No P20036
Gene Accession NP_291032
WB Predicted band size
WB Positive control P111841-WB-1-P
WB Recommended dilution 29 kDa
IHC predicted cell location Predicted cell location: Cell membrane
IHC positive control Positive control: Human tonsil
IHC Recommed dilution Recommended dilution: 40-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P111841-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or HLA-DPA1 antigen-treated (Neutralization experiment) using P111841(HLA-DPA1 Antibody) at dilution 1/35

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