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Sku: P102098-50 μl
Categories: Primary Antibodies

Specification

Full name CCR8 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
Swissprot No P51685
Gene Accession NP_005192
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue or CCR8 antigen-treated (Neutralization experiment) using P102098(CCR8 Antibody) at dilution 1/20
WB Positive control P102098-WB-1-P
WB Recommended dilution 41 kDa
IHC predicted cell location Predicted cell location: cytoplasm
IHC positive control Positive control: Human liver cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P102098-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or CCR8 antigen-treated (Neutralization experiment) using P102098(CCR8 Antibody) at dilution 1/20

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