HPLC Column Void Volume Calculator

Estimate the geometric volume and void volume of an HPLC column from its dimensions.

Column length (mm)

Column internal diameter (mm)

Total porosity (fraction)

Typical fully-porous particle columns run ~0.60–0.70; adjust if your column's spec sheet lists a different value.

Void volume here is estimated as geometric column volume × total porosity. This is an approximation — for precise work, measure void volume experimentally (e.g. with an unretained marker).

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