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Sku: P111728-50 μl
Categories: Primary Antibodies

Specification

Full name GLUD1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
Swissprot No P00367
Gene Accession NP_005262
WB Predicted band size
WB Positive control P111728-WB-1-P
WB Recommended dilution 61 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human tonsil
IHC Recommed dilution Recommended dilution: 20-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P111728-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or GLUD1 antigen-treated (Neutralization experiment) using P111728(GLUD1 Antibody) at dilution 1/20

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