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Specification
| Full name | EIF4G1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
| Swissprot No | Q04637 |
| Gene Accession | NP_004944 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or EIF4G1 antigen-treated (Neutralization experiment) using P102725(EIF4G1 Antibody) at dilution 1/30 |
| WB Positive control | P102725-WB-1-P |
| WB Recommended dilution | 175 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human thyroid cancer |
| IHC Recommed dilution | Recommended dilution: 25-100 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P102725-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or EIF4G1 antigen-treated (Neutralization experiment) using P102725(EIF4G1 Antibody) at dilution 1/30
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