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Sku: P290298-50 μl
Categories: Primary Antibodies

Specification

Full name CHRNA4 rabbit monoclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit monoclonal
Applications WB
Host Rabbit
Clone type rabbit monoclonal
Target Background This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Swissprot No P43681
Gene Accession 1137
WB Predicted band size
WB Positive control P290298-WB-1-P
WB Recommended dilution 70 kDa
IHC predicted cell location
IHC positive control
IHC Recommed dilution

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P290298-WB-1-P

When can I expect my order to ship?

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