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Specification
| Full name | CDK6 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. |
| Swissprot No | Q00534 |
| Gene Accession | BC052264 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or CDK6 antigen-treated (Neutralization experiment) using P100163(CDK6 Antibody) at dilution 1/55 |
| WB Positive control | P100163-WB-1-P |
| WB Recommended dilution | 37 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human liver cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P100163-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or CDK6 antigen-treated (Neutralization experiment) using P100163(CDK6 Antibody) at dilution 1/55
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Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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