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Sku: P108079-50 μl
Categories: Primary Antibodies

Specification

Full name CDH3 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).
Swissprot No P22223
Gene Accession BC014462
WB Predicted band size
WB Positive control P108079-WB-1-P
WB Recommended dilution 91 kDa
IHC predicted cell location Predicted cell location: Cell membrane
IHC positive control Positive control: Human cervical cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P108079-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or CDH3 antigen-treated (Neutralization experiment) using P108079(CDH3 Antibody) at dilution 1/90

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