Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the clotting process. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of...
Bcakground Interleukin 5 (IL5) , is a secreted glycoprotein that belongs to the alpha -helical group of cytokines (1 - 3). IL5 is present as a covalently linked antiparallel dimer...
A serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated...
The Insulin Receptor (gene name INSR, designated CD220) is a type I transmembrane glycoprotein in the Insulin/IGF Receptor family of receptor tyrosine kinases that share structural similarity and overlapping intracellular...
Bcakground Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12...
Bcakground Interleukin-21(IL-21) is an approximately 14 kDa four-helix-bundle cytokine in the family of cytokines that utilize the common gamma chain as a receptor subunit. gamma c is also a subunit...
The human Sftpd is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The protein may also be involved in surfactant metabolism.
Bcakground Recombinant mouse LIF (leukemia inhibitory factor) is commonly used in cell culture to maintain the pluripotency of stem cells. LIF is a widely expressed pleiotropic member of the IL-6...