Bcakground Interferon-gamma (IFN-gamma) , also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine (1, 2)....
Bcakground Interleukin-7 (IL-7)is a 25 kDa cytokine of the hemopoietin family that plays important roles in lymphocyte differentiation, proliferation, and survival (1 -4). Mouse IL-7 cDNA encodes 154 amino acids...
Bcakground Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a secreted protein that belongs to the IL-4 / IL-13 family (1-3). It is a glycosylated polypeptide that contains three...
Background TGF-β1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-β superfamily that share a characteristic cystine knot structure (1–7). TGF-β1, -2,...
Bcakground Interleukin-4 (IL-4) , also known as B cell-stimulatory factor-1, is a monomeric, approximately Th2 cytokine that shows pleiotropic effects during immune responses (1-4). Mature mouse IL-4 shares 39%, 39%,...
Most cell types express three sizes of receptors for TGF-beta. These are designated type I (53 kDa), type II (70-85 kDa), and type III (250-350 kDa). The type II receptor...
Bcakground Stem cell factor (SCF)is a potent hematopoietic growth factor required in regulating both embryonic and adult hematopoiesis. SCF protein promotes the survival, differentiation, and mobilization of multiple cell types...