Synonym(s): Octadecanoic acid Description CG 201, Stearic acid, is a fatty acid obtained by saponification of the triglycerides. It is a saturated linear C18 carboxylic acid. The triglyceride of stearic...

Description Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production. In...

  Description: N-Acetyl-D-galactosamine (GalNAc) is an amino sugar derivative of galactose. In humans it is the terminal carbohydrate forming the antigen of blood group A.   Typical Properties:  Typical Properties:  ...

Synonym(s): Hexanedioic acid, Hexane-1,6-dioic acid, 1,4-butane dicarboxylic acid Description CG 212, Adipic acid also known as hexanedioic acid, is one of the highest volume dicarboxylic acid in the chemical market. It...

Description RMC-0331 is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction. Specification Catalog...

Description MLN-4924 (Pevonedistat) is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN-4924 binds to and inhibits NAE, which may result in the...

Description BDTX-1535 is an orally bioavailable, brain-penetrating, mutation-selective, EGFR inhibitor with potential antitumor activity.BDTX-1535 is a fourth-generation EGFR inhibitor that overcomes resistance to Osimertinib, the standard of care for EGFR-mutant...

Description Danirixin (GSK1325756) is an orally active, selective CXC chemokine receptor 2 (CXCR2) antagonist with 78-fold lower affinity toward CXCR1 (CXCR2/CXCR1 IC50 = 12.5/977 nM by competitive binding against 0.225...