Description RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants (a RASMULTI(ON) inhibitor). Preclinically, RMC-7977 demonstrated potent...
Description Glyceryl Monooleate is a clear or light yellow oil that is used as an antifoam in juice processing. It has been used as an emulsifier, a moisturizer, and a...
Description 2-Ethylhexyl Phosphate is a mixture of mono and di-esters that finds applications as an extractant for the separation of rare earth metals, actinides, and lanthanides in the nuclear industry....
Description Tolyltriazole is a heterocyclic organic compound. It is a white to slightly yellowish powder and belongs to the triazole group. Tolyltriazole has similar applications to benzotriazole as a corrosion...
Product Description DPBS, called “Dulbecco's Phosphate Buffered Saline”, is a balanced salt solution widely used in biology.This DPBS does not contain calcium and magnesium, and can be used for washing...
Description X-Glucis a chemicalcompound with themolecular formula C14H13BrClNO7. It is utilized as a reagent fordetectingβ-glucuronidase. This enzymeis produced byEscherichia coli (E.coli) andis employed fordetectingcontaminationof E.coliin food, waterandurinary pathways.Additionally, X-Gluc finds...
Description Olpasiran is a first-in-class, high-purity small interfering RNA (siRNA) designed to target and inhibit Lipoprotein(a) [Lp(a)] mRNA translation in hepatocytes, thereby reducing plasma Lp(a) concentration. As a precision molecular...
Product Composition Component 8015151 8015152 Instant TBS-TBlocking Buffer 20 packs/box 100 packs/box Note: The pH value of 1 × solution is 7.4±0.2@25°C. Storage and Transportation Conditions Store at room...
Product Composition Component 8015131 8015132 Instant TBS-T Buffer 20 packs/box 100 packs/box Note: The pH value of 1 × solution is 7.4±0.2@25°C. Storage and Transportation Conditions Store at room...
Product Composition Component 8005011 8005012 Instant PBS Buffer 20 packs/box 100 packs/box Note: The pH value of 1 × solution is 7.4±0.2@25°C. Storage and Transportation Conditions Store at room temperature...
Description RMC-0331 is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction. Specification Catalog...
GENERAL INFORMATION CAS Number 1199-60-6 Product Name 5-Methoxy-4-oxo-4H-pyran-2-carboxylic acid IUPAC Name 5-methoxy-4-oxopyran-2-carboxylic acid Molecular Formula C7H6O5 Molecular Weight 170.12 g/mol InChI InChI=1S/C7H6O5/c1-11-6-3-12-5(7(9)10)2-4(6)8/h2-3H,1H3,(H,9,10) InChI Key JQYYVBCIIMRLDL-UHFFFAOYSA-N SMILES COC1=COC(=CC1=O)C(=O)O Canonical SMILES COC1=COC(=CC1=O)C(=O)O...
Product No. D-6275 Product Name L-Lysine-2,6,6-d3 HCl Quantity 0.25 g 0.5 g Synonym(s) (S)-2,6-Diaminohexanoic Acid HCl; H-L-Lys-OH HCl Isotopic Enrichment 98 atom % D Formula H2NCD2(CH2)3CD(NH2)COOH•HCl Structure Molecular Weight 185.67...
Description PLX-5622 is a highly selective brain-penetrant CSF1R inhibitor (IC50=0.016 µM; Ki=5.9 nM) allowing for extended and specific microglial elimination, preceding and during pathology development. Key Features CSF1R Inhibition: PLX-5622...
Description MLN-4924 (Pevonedistat) is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN-4924 binds to and inhibits NAE, which may result in the...
Description BDTX-1535 is an orally bioavailable, brain-penetrating, mutation-selective, EGFR inhibitor with potential antitumor activity.BDTX-1535 is a fourth-generation EGFR inhibitor that overcomes resistance to Osimertinib, the standard of care for EGFR-mutant...
Description BI-2865 is a pan-KRAS inhibitor disables oncogenic signalling and tumour growth. BI-2865 blocks nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants,...
Description: BMS-906024 is an orally active and selective γ-secretase (gamma secretase) inhibitor. BMS-906024 is a potent pan-Notch receptors inhibitor with IC50s of 1.6 nM, 0.7 nM, 3.4 nM, and 2.9...
Description: Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide class. It is derived from several strains of streptomycetes. Typical Properties: Form: white to off-white powder...
Description: Methylcobalamin is a vitamin B12 analog. Typical Properties: Typical Properties: Form: Dark red crystalline or crystalline powder Purity (on dry basis): 98% Min Loss on drying 12%...
Description: β-Diphosphopyridine nucleotide consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other one contains an nicotinamide. It is a coenzyme central to...
Description: Adenosine is one of the four nucleoside building blocks to DNA and RNA. Typical Properties: Typical Properties: Form: powder Assay ≥99% Quality Level 200 mp 234-236 °C...