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Sku: OM641860
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Product Profile

Product Name Anti-HEXB antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide

 

 

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAICC/IFIHCWB
  WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species Reactivity HumanMouseRat
Concentration 1 mg/ml
Purification Protein A

 


Target Information

Gene Symbol HEXB
Gene Synonyms
ENC-1AS
HEL-248
HEL-S-111
Gene Full Name hexosaminidase subunit beta
Gene Summary
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
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Molecular Weight(MW) 63 KDa
Source Rabbit
Cellular Localization Lysosome
Purification Protein A

 

 

Application

WB

Western blot analysis using HEXB antibody against THp-1 (1),A431(2) cell lysate.

 

IHC

Immunohistochemical analysis of paraffin-embedded lung cancer tissues using HEXB antibody with DAB staining.

 

ICC/IF

Immunofluorescence analysis of Hela cells using HEXB antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

 

Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

 

 

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

Email contact@biofargo.com if you have any requirements.

 

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