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$420.00
Sku: Y12101-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 20, 2026
Description
PDGF-AB (Platelet-Derived Growth Factor-AB) is an important dimeric protein growth factor belonging to the PDGF family, formed by one A chain and one B chain linked via disulfide bonds. It is primarily secreted by platelets, endothelial cells, macrophages, and other cell types. In mesenchymal stem cell (MSC) culture, PDGF-AB promotes proliferation and helps maintain multipotent differentiation potential. It also inhibits apoptotic pathways and enhances cell survival, which is particularly critical under serum-free or low-serum culture conditions. PDGF-AB plays a key role in tissue repair, embryonic development, and cell proliferation.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y12101 |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Measure in a cell proliferation assay using NIH3T3 cells. The ED50 is ≤1.0 ng/mL. |
| Alternative Names | PDGFAB; PDGF-AB |
| Species | Human |
| Expression System | CHO |
| Mol. Weight | 14.3 kDa & 12.3 kDa |
| Expression Region | Ser87-Thr211 & Ser82-Thr190 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. |
| Size | 50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Stem Cell Research
Enhances MSC proliferation and angiogenic support in vitro.
Cell Biology
Stimulates mesenchymal cell proliferation and migration.
Data Figures
Figure 1: Measured in a cell proliferation assay using NlH3T3 cells. The ED50 is ≤ 1.0ng/mL.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
