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$276.00
Sku: Y06021H-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 20, 2026
Description
FGF-8b (Fibroblast Growth Factor 8b), an important member of the FGF family, is a splice variant of the FGF-8 isoform composed of 194 amino acids. It possesses heparin-binding capacity and can activate downstream signaling pathways by interacting with heparan sulfate proteoglycans (HSPGs). FGF-8b promotes cell proliferation, survival, and migration, playing significant roles in neural development, mesoderm formation, and carcinogenesis. It can be utilized to maintain the undifferentiated state of embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs), and works synergistically with factors such as BMP and WNT to promote the proliferation and directed differentiation of neural precursor cells.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y06021H |
| Purity | ≥95%, by SDS-PAGE (under conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Measured in a cell proliferation assay using NlH3T3 cells. The ED50 is ≤1.0 ng/ml. |
| Accession | P55075.3 |
| Species | Human |
| Expression System | E. coli |
| Mol. Weight | 22.4 kDa |
| Expression Region | Gln23-Arg215 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | Lyophilized from a 0.22 μm-filtered solution containing 10 mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Stem Cell Research
Supports neural and embryonic stem cell proliferation and patterning.
Cell Biology
Involved in developmental patterning and cell differentiation, especially in neural tissues.
Data Figures
Figure 1: Measured in a cell proliferation assay using NIH3T3 cells.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
