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$117.00
Sku: Y05421H-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 20, 2026
Description
FGF-1 (Fibroblast Growth Factor-1 (Acidic)), also known as aFGF, is an important cell growth factor belonging to the FGF family. Its molecular core consists of a β-trefoil topological structure composed of 12 β-strands stabilized by disulfide bonds. It plays a key role in cell proliferation, differentiation, and tissue repair. FGF-1 can promote the proliferation of various cell types, such as fibroblasts, endothelial cells, neural cells, and stem cells. In serum-free culture media, when used in combination with other factors (such as TGF-β), it can inhibit stem cell differentiation and maintain their undifferentiated state.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y05421H |
| Purity | ≥95%, by SDS-PAGE (under reducing (R)&Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Measured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect ≤2.0 ng/mL. |
| Accession | NP_001127073.1 |
| Species | Human |
| Expression System | E. coli |
| Mol. Weight | 15.8 kDa |
| Expression Region | F16-D155 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | Lyophilized from a 0.22 μm-filtered solution containing 20 mM PB, 5% Trehalose, 100 mM NaCl and 0.05% Tween 80, pH6.0. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Stem Cell Research
Promotes proliferation and survival of various stem cells, including mesenchymal and endothelial stem cells.
Cell Biology
Stimulates cell proliferation, differentiation, and survival via FGFR-mediated signaling.
Data Figures
Figure 1: Measured in a cell proliferation assay using NIH3T3 cells.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
