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$504.00
Sku: Y10801-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 20, 2026
Description
BMP-9 (Bone Morphogenetic Protein 9), also known as Growth Differentiation Factor-2 (GDF-2), belongs to the TGF-β superfamily. It signals through heteromeric complexes composed of type I and type II BMP receptors and has been identified in recent years as a bone morphogenetic protein with exceptionally potent osteoinductive activity. BMP-9 can induce osteogenic differentiation in various cell types, including osteoblasts, osteoprogenitor cells, and other committed stem cells.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y10801 |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is ＜2.0 ng/mL. |
| Accession | Q9UK05 |
| Species | Human |
| Expression System | HEK293 |
| Mol. Weight | 12.1 kDa (monomer) |
| Expression Region | Ser320-Arg429 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | 0.085% TFA, 30% ACN, 5% Mannitol, pH2.5. |
| Size | 50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in 4 mM HCl. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Stem Cell Research
Potent inducer of osteogenic differentiation in MSCs and progenitors.
Cell Biology
Controls osteogenesis, angiogenesis, and metabolic regulation through SMAD signaling.
Data Figures
Figure 1: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is ＜2.0 ng/mL. The activity of recombinant Human BMP-9 (Cat. No. Y10801) is higher than the other competing product.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
