BioUltra, suitable for cell culture, suitable for plant cell culture, ≥99% (titration)

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Sku: BO92505
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Description

Glycerophosphoric acid disodium salt hydrate, also known as BGP, is a versatile compound with applications across various research domains, including cell biology, biochemical research, and metabolomics. Recognized as an endogenous metabolite and a serine-threonine phosphatase inhibitor, BGP is extensively utilized in chitosan hydrogel formulations for drug delivery research. It serves as a phosphate source for cell growth and recombinant protein production, offering advantages in media formulations by reducing precipitation at higher pH levels. Additionally, BGP finds applications in micro-arc oxidation electrolyte solutions, contributing to the creation of photocatalytic coatings.

In cell biology, β-Glycerophosphate disodium salt plays a pivotal role as a phosphate group donor in matrix mineralization studies and accelerates calcification in vascular smooth muscle cells. It also promotes bone matrix mineralization when delivered to osteoblasts, providing a crucial source of phosphate ions. In the realm of biochemical research, BGP functions as a classical serine-threonine phosphatase inhibitor in kinase reaction buffers, offering broad-spectrum inhibition. Its role as an organic phosphate donor is particularly valuable in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. Moreover, BGP is utilized to buffer M17 media for Lactococcus culture in recombinant protein expression. The comprehensive utility of BGP spans multiple areas of research, making it an essential component in studies encompassing cell biology, biochemical research, and metabolomics.

Features

  • Versatile and adaptable for a wide variety of laboratory and research applications

  • Suitable for Cell culture and Plant cell culture

  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications

  • BioUltra Grade for your Cell Biology and Biochemical research

Application

  • β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.

  • Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Quality

Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.

Specifications

Synonym BGP; Glycerol 2-phosphate disodium salt hydrate
CAS Number 154804-51-0
Empirical Formula (Hill Notation) C3H7Na2O6P · xH2O
Molecular Weight 216.04 (anhydrous basis)
EC Number 212-464-3
MDL Number MFCD00149082
Linear Formula (HOCH2)2CHOP(O)(ONa)2 · xH2O
Product Type Chemical
Purity ≥99% (titration)
mp 102-104 °C (lit.)
UNSPSC 12352201

 

Properties

Anion Traces chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
Assay ≥99% (titration)
Biological Source synthetic (chemical)
Cation Traces Al: ≤0.001%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.0005%
Pb: ≤0.001%
Zn: ≤0.0005%
Color white
Form powder
Impurities ≤0.1% Insoluble matter
≤0.5 mol % L-α-isomer
InChI 1S/C3H9O6P.2Na.H2O/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2
InChI Key ROPZSVKNEIIIDE-UHFFFAOYSA-L
mp 102-104 °C (lit.)
Product Line BioUltra
Quality Level 400
SMILES String O.[Na+][Na+].OCC(CO)OP([O-][O-])=O
Solubility water: soluble
Technique(s) cell culture | mammalian: suitable
cell culture | plant: suitable

 

Safety Info.

RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable

 

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

Email contact@biofargo.com if you have any requirements.

 

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