Bcakground Interferon alpha 8 (IFNA8) also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid s equence homology. They are...
Bcakground Interferon-gamma (IFN-gamma), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine (1, 2). Mature...
Bcakground Insulin-like Growth Factor I (IGF-I) , also known as Somatomedin C, is the dominant effector of Growth Hormone (GH) and is structurally homologous to Proinsulin. Human IGF-I is synthesized...
IGF-I receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha and two beta subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA....
Bcakground Insulin-like Growth Factor II (IGF-II) is a potent mitogenic growth factor. However, unlike IGF-I which has important postnatal roles, the growth -promoting function of IGF-II is limited to embryonic...
Bcakground Insulin-like growth factor binding protein-3 (IGFBP-3)is one of six members of the insulinlike growth factor (IGF) binding protein superfamily which function to modulate the biological activity of IGF (1)....
Bcakground The hedgehog (hh) gene encoding a secreted protein was originally identified in Drosophila as a segment polarity gene. The vertebrate homologues of Hh comprise several proteins including sonic hedgehog...