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Full name | UGT1A4 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. |
Swissprot No | P22310 |
Gene Accession | NP_009051 |
WB Predicted band size | |
WB Positive control | P113814-WB-1-P |
WB Recommended dilution | 60 kDa |
IHC predicted cell location | Predicted cell location: Cell membrane |
IHC positive control | Positive control: Human brain |
IHC Recommed dilution | Recommended dilution: 10-50 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P113814-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human brain tissue or UGT1A4 antigen-treated (Neutralization experiment) using P113814(UGT1A4 Antibody) at dilution 1/20
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