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Sku: P113814-50 μl
Categories: Primary Antibodies

Specification

Full name UGT1A4 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.
Swissprot No P22310
Gene Accession NP_009051
WB Predicted band size
WB Positive control P113814-WB-1-P
WB Recommended dilution 60 kDa
IHC predicted cell location Predicted cell location: Cell membrane
IHC positive control Positive control: Human brain
IHC Recommed dilution Recommended dilution: 10-50

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P113814-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human brain tissue or UGT1A4 antigen-treated (Neutralization experiment) using P113814(UGT1A4 Antibody) at dilution 1/20

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