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Full name | RBM8A rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. |
Swissprot No | Q9Y5S9 |
Gene Accession | BC017088 |
WB Predicted band size | |
WB Positive control | P109218-WB-1-P |
WB Recommended dilution | 20 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human lung cancer |
IHC Recommed dilution | Recommended dilution: 25-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P109218-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or RBM8A antigen-treated (Neutralization experiment) using P109218(RBM8A Antibody) at dilution 1/30
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