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Sku: P109218-50 μl

Specification

Full name RBM8A rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.
Swissprot No Q9Y5S9
Gene Accession BC017088
WB Predicted band size
WB Positive control P109218-WB-1-P
WB Recommended dilution 20 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human lung cancer
IHC Recommed dilution Recommended dilution: 25-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P109218-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or RBM8A antigen-treated (Neutralization experiment) using P109218(RBM8A Antibody) at dilution 1/30

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