Biochemical reagents

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Description PLX-5622 is a highly selective brain-penetrant CSF1R inhibitor (IC50=0.016 µM; Ki=5.9 nM) allowing for extended and specific microglial elimination, preceding and during pathology development. Notice: PLX-5622 also works well...

MLN-4924 (Pevonedistat)

Description MLN-4924 (Pevonedistat) is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN-4924 binds to and inhibits NAE, which may result in the...


Description RMC-6236 is a first-in-class, potent, oral RAS-selective tri-complex, RAS(MULTI)(ON) inhibitor with an attractive preclinical profile and is designed to treat cancers caused by multiple RAS variants for which no...


DescriptionBDTX-1535 is an orally bioavailable, brain-penetrating, mutation-selective, EGFR inhibitor with potential antitumor activity.BDTX-1535 is a fourth-generation EGFR inhibitor that overcomes resistance to Osimertinib, the standard of care for EGFR-mutant non–small...


BI-2865 is a pan-KRAS inhibitor disables oncogenic signalling and tumour growth. BI-2865 blocks nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants, including...

BMS-906024, Purity: 98.10%

Description: BMS-906024 is an orally active and selective γ-secretase (gamma secretase) inhibitor. BMS-906024 is a potent pan-Notch receptors inhibitor with IC50s of 1.6 nM, 0.7 nM, 3.4 nM, and 2.9...

Dextran Sulfate Sodium Salt (DSS) MW:36000~50000

Dextran sulfate sodium salt (DSS) is a polyanionic derivative of dextran produced by the esterification of Dextran with chlorosulphonic acid. The sulfur content is approximately 17% which corresponds to an...

Hygromycin B

Hygromycin B, an aminoglycoside antibiotic synthesized by Streptomyces hygroscopicus, inhibits protein synthesis by interfering with 70S ribosomal translocation and inducing misreading of mRNA template, thus killing prokaryotes (such as bacteria),...

G418 Sulfate (Geneticin)

G418 Sulfate, also known as Geneticin Sulfate, is an amino-glycoside antibiotic and structurally similar to Gentamycin B1. It interfers with protein synthesis by binding 80s ribosome and blocking elongation steps....

Tetracyclin HCl

Tetracycline HCl is a broad-spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria, exhibiting activity against a wide range of Gram-positive and Gram-negative bacteria. It exerts a bacteriostatic effect...

Puromycin (Solution 10 mg/mL)

Puromycin is an aminoglycoside antibiotic produced by fermentation and metabolism of Streptomyces alboniger, which kills Gram-positive bacteria, and various animal and insect cells by inhibiting protein synthesis. Puromycin is effective...

Neomycin Sulfate

Neomycin sulfate from Yeasen is supplied in the form of white powder and is a USP-grade reagent with a solubility of about 200 mg/mL in water. It is an aminoglycoside...

Kanamycin Sulfate

Kanamycin sulfate, also known as Kanamycin sulfate or Kanamycin A, is an aminoglycoside bacteriocidal antibiotic and can be used as a selection agent for bacteria. This product from Yeasen is...

Chloramphenicol, USP Grade

Chloramphenicol, also known as Chloromycetin, Chlornitromycin, or Levomycetin, is a broad-spectrum antibiotic. USP Grade Chloramphenicol is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as...

Ampicillin, Sodium Salt

Ampicillin is a β-lactam antibiotic within the penicillin family. As a member of this family, Ampicillin is susceptible to β-lactamase, which hydrolyzes the β-lactam ring. This broad-spectrum antibiotic is effective...