Biochemical reagents

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PLX-5622

Description PLX-5622 is a highly selective brain-penetrant CSF1R inhibitor (IC50=0.016 µM; Ki=5.9 nM) allowing for extended and specific microglial elimination, preceding and during pathology development. Notice: PLX-5622 also works well...
$50.00

MLN-4924 (Pevonedistat)

Description MLN-4924 (Pevonedistat) is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN-4924 binds to and inhibits NAE, which may result in the...
$80.00

RMC-6236

Description RMC-6236 is a first-in-class, potent, oral RAS-selective tri-complex, RAS(MULTI)(ON) inhibitor with an attractive preclinical profile and is designed to treat cancers caused by multiple RAS variants for which no...
$1,300.00

BDTX-1535

DescriptionBDTX-1535 is an orally bioavailable, brain-penetrating, mutation-selective, EGFR inhibitor with potential antitumor activity.BDTX-1535 is a fourth-generation EGFR inhibitor that overcomes resistance to Osimertinib, the standard of care for EGFR-mutant non–small...
$190.00

BI-2865

BI-2865 is a pan-KRAS inhibitor disables oncogenic signalling and tumour growth. BI-2865 blocks nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants, including...
$450.00

BMS-906024, Purity: 98.10%

Description: BMS-906024 is an orally active and selective γ-secretase (gamma secretase) inhibitor. BMS-906024 is a potent pan-Notch receptors inhibitor with IC50s of 1.6 nM, 0.7 nM, 3.4 nM, and 2.9...
$500.00

Dextran Sulfate Sodium Salt (DSS) MW:36000~50000

Dextran sulfate sodium salt (DSS) is a polyanionic derivative of dextran produced by the esterification of Dextran with chlorosulphonic acid. The sulfur content is approximately 17% which corresponds to an...
$242.25

Hygromycin B

Hygromycin B, an aminoglycoside antibiotic synthesized by Streptomyces hygroscopicus, inhibits protein synthesis by interfering with 70S ribosomal translocation and inducing misreading of mRNA template, thus killing prokaryotes (such as bacteria),...
$261.25

G418 Sulfate (Geneticin)

G418 Sulfate, also known as Geneticin Sulfate, is an amino-glycoside antibiotic and structurally similar to Gentamycin B1. It interfers with protein synthesis by binding 80s ribosome and blocking elongation steps....
$61.75

Tetracyclin HCl

Tetracycline HCl is a broad-spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria, exhibiting activity against a wide range of Gram-positive and Gram-negative bacteria. It exerts a bacteriostatic effect...
$71.25

Puromycin (Solution 10 mg/mL)

Puromycin is an aminoglycoside antibiotic produced by fermentation and metabolism of Streptomyces alboniger, which kills Gram-positive bacteria, and various animal and insect cells by inhibiting protein synthesis. Puromycin is effective...
$42.75

Neomycin Sulfate

Neomycin sulfate from Yeasen is supplied in the form of white powder and is a USP-grade reagent with a solubility of about 200 mg/mL in water. It is an aminoglycoside...
$33.25

Kanamycin Sulfate

Kanamycin sulfate, also known as Kanamycin sulfate or Kanamycin A, is an aminoglycoside bacteriocidal antibiotic and can be used as a selection agent for bacteria. This product from Yeasen is...
$128.25

Chloramphenicol, USP Grade

Chloramphenicol, also known as Chloromycetin, Chlornitromycin, or Levomycetin, is a broad-spectrum antibiotic. USP Grade Chloramphenicol is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as...
$23.75

Ampicillin, Sodium Salt

Ampicillin is a β-lactam antibiotic within the penicillin family. As a member of this family, Ampicillin is susceptible to β-lactamase, which hydrolyzes the β-lactam ring. This broad-spectrum antibiotic is effective...
$71.25
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