Specification

Full name	Rb1 rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and enzyme binding activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; negative regulation of myofibroblast differentiation; and negative regulation of transcription involved in G1/S transition of mitotic cell cycle. Acts upstream of or within several processes, including hepatocyte apoptotic process; neuron development; and regulation of transcription by RNA polymerase II. Located in nucleus and spindle. Part of Rb-E2F complex. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; retina; and vibrissa. Human ortholog(s) of this gene implicated in nervous system cancer (multiple); osteosarcoma; prostate cancer; small cell carcinoma; and urinary bladder cancer. Orthologous to human RB1 (RB transcriptional corepressor 1). [provided by Alliance of Genome Resources, Apr 2022]
Swissprot No	P13405
Gene Accession	19645
WB Predicted band size	105 kDa
WB Positive control
WB Recommended dilution	500-2000
IHC predicted cell location	nan
IHC positive control	nan
IHC Recommed dilution	nan

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

P291735-WB-1-P