Specification

Full name	PRC1 (phospho-Thr481) rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB, IHC, IF
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Swissprot No	O43663
Gene Accession	9055
WB Predicted band size
WB Positive control	P291204-WB-1-P
WB Recommended dilution	72 kDa
IHC predicted cell location	Predicted cell location: Cytoplasm and Nucleus
IHC positive control	Positive control: Human lung cancer
IHC Recommed dilution	Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

P291204-WB-1-P

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using P291204(PRC1 (phospho-Thr481) Antibody) at dilution 1/50