Specification

Full name	CASP3 (active) rabbit polyclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit polyclonal
Applications	WB, IHC
Host	Rabbit
Clone type	rabbit polyclonal
Target Background	The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Swissprot No	P42574
Gene Accession	NP_116786
WB Predicted band size	17 kDa
WB Positive control
WB Recommended dilution	1000-5000
IHC predicted cell location	Predicted cell location: Cytoplasm
IHC positive control	Positive control: Human colorectal cancer
IHC Recommed dilution	Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P109536-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or CASP3 (active) antigen-treated (Neutralization experiment) using P109536(CASP3 (active) Antibody) at dilution 1/50

CASP3 (active) rabbit polyclonal antibody