Description

Tirzepatide GLN24 deamidation impurity is a high-purity impurity reference standard for pharmaceutical quality control and analytical testing of Tirzepatide. Deamidation at glutamine position 24 can occur during storage or accelerated stress conditions and may impact peptide stability and analytical profile. This reference standard is essential for monitoring degradation pathways by HPLC and LC-MS, ensuring batch-to-batch consistency of Tirzepatide drug substance and drug product.

Specifications

Parameter	Specification
API Category	Tirzepatide Impurity
Appearance	Off-white lyophilized powder
Catalog Number	BF-Q24
CAS Number	N/A
Molecular Formula	N/A
Molecular Weight	N/A
Solubility	20% ACN in water
Storage Condition	-20±5°C, protect from light and moisture
Synonyms	GLN24 deamidation variant

Applications

Pharmaceutical impurity profiling and quality control
HPLC and LC-MS/MS method development and validation
Drug substance and drug product release testing
Stability studies and forced degradation analysis
Regulatory submission support (FDA, EMA, ICH guidelines)

Documents

MSDS

COA

Tirzepatide GLN24 (Q24) Deamidation Impurity Reference Standard