Specification

Full name	TAOK1/TAOK2/TAOK3 (phospho-Ser181/Ser181/Ser177) rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB, IHC
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	TAOK1 enables alpha-tubulin binding activity; beta-tubulin binding activity; and kinase activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; negative regulation of microtubule depolymerization; and positive regulation of JNK cascade. Located in microtubule cytoskeleton and perinuclear region of cytoplasm. TAOK2 enables mitogen-activated protein kinase kinase binding activity; neuropilin binding activity; and protein serine/threonine kinase activity. Involved in several processes, including focal adhesion assembly; intracellular signal transduction; and positive regulation of JNK cascade. Located in cytoplasmic vesicle; cytosol; and nuclear lumen. Part of receptor complex. The protein encoded by the TAOK3 gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases.
Swissprot No	Q7L7X3/Q9UL54/Q9H2K8
Gene Accession	57551/9344/51347
WB Predicted band size	116 kDa
WB Positive control
WB Recommended dilution	500-2000
IHC predicted cell location	Predicted cell location: Cytoplasm
IHC positive control	Positive control: Human tonsil
IHC Recommed dilution	Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P291517-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using P291517(TAOK1/TAOK2/TAOK3 (phospho-Ser181/Ser181/Ser177) Antibody) at dilution 1/50

TAOK1/TAOK2/TAOK3 (phospho-Ser181/Ser181/Ser177) rabbit monoclonal antibody