Background

Claudin18.2 (CLDN18.2) is a splice variant of the tight junction protein Claudin18. Aberrantly expressed in gastric, pancreatic, biliary, ovarian, and lung adenocarcinomas, CLDN18.2 has emerged as a promising pan-cancer target for immunotherapy. It has restricted expression in normal gastric mucosa, making it a valuable biomarker for research and drug development.

Specifications

Product Overview	Recombinant Mouse Anti-CLDN18.2 Antibody (clone 43-14A)
Description	Epitope: C-terminal, EVQSYPSKHDYV
Host	Mouse
Species Reactivity	Human
Isotype	Mouse IgG, κ
Specificity Target	CLDN18.2
Purity	90% SDS-PAGE
Form	Liquid
Buffer	PBS, pH 7.5
Concentration	1.40 mg/ml (lot specific)
Application	Pathology IHC
Storage	Store at -20℃ before reconstitution. Avoid freeze-thaw cycle.
Synonyms	Claudin-18.2; CLDN18 splice variant 2; Claudin 18 isoform 2; Claudin-18 gastric isoform

Data

Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue with Mouse anti-Claudin 18.2 antibody at 1/50 dilution.

Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue with Mouse anti-Claudin 18.2 antibody at 1/50 dilution.

Documents

Claudin 18.2 Mouse Monoclonal Antibody(ARA848)