{"product_id":"recombinant-human-il-2","title":"Recombinant Human IL-2","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n\u003cp style=\"margin: 0; text-align: justify;\"\u003eRecombinant Human Interleukin-2 (IL-2) is a cytokine that plays a central role in the regulation of immune responses. It is primarily produced by activated T lymphocytes and promotes the proliferation, differentiation, and survival of T cells, B cells, and natural killer (NK) cells. This recombinant IL-2 protein is expressed in CHO cells and corresponds to the mature human IL-2 sequence (Ala21–Thr153), ensuring proper folding and post-translational modifications. With high purity (≥95%) and strong bioactivity (≥1 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg), this product is suitable for a wide range of immunological and cell biology studies. The protein is supplied in a tag-free, lyophilized form, making it convenient for reconstitution and downstream applications.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\n\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n\u003cth colspan=\"2\" style=\"padding: 12px; text-align: left;\"\u003eProduct Details\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eY02001N\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤1 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003e≥1 x 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg. Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP60568-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e15.4 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eAla21-Thr153\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e100μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"26%\" style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e High Purity: This product undergoes stringent purification processes, achieving a purity level of ≥95%, ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Exhibits a bioactivity of ≥1 × 10⁷ IU\/mg, validated by CTLL-2 cell proliferation assay, ensuring strong and consistent performance in functional studies.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eMammalian Expression System:\u003c\/strong\u003e Expressed in CHO cells to ensure proper protein folding and native post-translational modifications, enhancing biological relevance.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eLow Endotoxin:\u003c\/strong\u003e Endotoxin level is ≤1 EU\/mg, making it suitable for sensitive cell-based assays and immune-related studies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates hematopoietic balance under inflammation, favoring myeloid differentiation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePotent pro-inflammatory cytokine driving innate immunity and Th17 responses.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eParticipates in inflammation signaling, cell activation, and death regulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1729670532493493.jpg?v=1774942658\" alt=\"Measured by its ability to induce NF-kB reporter activity in MCF-7 cells.\" style=\"max-width: 100%; height: auto;\"\u003e\n\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human IL-2 (Cat. No. Y02001) stimulates proliferation of CTLL-2 cells. The specific bioactivity of Y02001 is ≥1 x 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg.\u003c\/p\u003e\n\u003c\/div\u003e\n  \u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1729670532493493_39eb05f2-dd7b-44e5-8e6b-f54cdf9725ef.jpg?v=1774943567\" alt=\"Measured by its ability to induce NF-kB reporter activity in MCF-7 cells.\" style=\"max-width: 100%; height: auto;\"\u003e\n\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Recombinant Human IL-2 (Cat. No. Y02001)  SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y02001 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n    \u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1729670532493493_1.jpg?v=1774943703\" alt=\"Measured by its ability to induce NF-kB reporter activity in MCF-7 cells.\" style=\"max-width: 100%; height: auto;\"\u003e\n\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 3: Highly consistent bioactivity between different production batches of Recombinant Human IL-2 (Cat. No. Y02001).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5;  padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"10ug","offer_id":52402187763893,"sku":"Y02001N-10ug","price":10.0,"currency_code":"USD","in_stock":true},{"title":"100ug","offer_id":52402187796661,"sku":"Y02001N-100ug","price":28.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52402187829429,"sku":"Y02001N-1mg","price":198.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1729670532493493_1_31de3e55-e6dc-4158-aa86-e024632bd1ba.jpg?v=1774944014","url":"https:\/\/biofargo.com\/products\/recombinant-human-il-2","provider":"Biofargo","version":"1.0","type":"link"}