Background

This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.

Specification

Full name	RAP1B rabbit polyclonal antibody
Alternative names	K-REV, RAL1B
Reactivity	Human, Mouse, Rat
Applications	WB, IHC
Host	Rabbit
Clone type	rabbit polyclonal
Conjugate	Unconjugate
Swissprot No	P61224
Gene Accession	BC000176
WB Predicted band size	21 kDa
WB Positive control	293T, Jurkat and NIH/3T3 cells
WB Recommended dilution	500-2000
IHC predicted cell location_1	Predicted cell location: Cytoplasm
IHC positive control_1	Positive control: Human thyroid cancer
IHC Recommed dilution	Recommended dilution: 50-200
IHC predicted cell location_2	Predicted cell location: Cytoplasm
IHC positive control_2	Positive control: Human gastric cancer
IHC Recommed dilution_2	Recommended dilution: 50-200

Application

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or RAP1B antigen-treated (Neutralization experiment) using P100121(RAP1B Antibody) at dilution 1/50

Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or RAP1B antigen-treated (Neutralization experiment) using P100121(RAP1B Antibody) at dilution 1/50

Western blot analysis of extracts from 293T cells, Jurkat cells, NIH/3T3 cells using P100121(RAP1B Antibody) at dilution 1/550

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

RAP1B rabbit polyclonal antibody