Description

Propylene glycol, a low-molecular-weight aliphatic alcohol, holds significance as a key solvent in biological and pharmaceutical formulation research. Its outstanding miscibility with water and diverse organic compounds, coupled with its low freezing point, low vapor pressure, and non-toxic nature, positions it as a preferred choice for a variety of research applications, particularly in sensitive biological assays and pharmaceutical preparations.

Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body.

The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.

Specifications

Grade	Reagent
Formula	C₃H₈O₂
MW	76.10
CAS	57-55-6
Appearance	Clear viscous liquid
Assay	≥99.0%
Residue on Ignition	≤0.01%
Sulfate	≤0.001%
Density (20°)	1.035 – 1.039 g/ml
Heavy Metals	≤0.0003%
Solubility in water	PASS
Oxidizing substances	PASS
Acidity (as H⁺)	≤0.05mmol/100g
Water(KF)	≤0.2%
Chloride	≤0.001%
Storage	Store at room temperature.

Application

Propylene glycol has been used:

for removing excess Oil Red O stain in zebrafish larvae
in the preparation of alginate hydrogels
for the dissolution of androstenone
for the calibration of cone beam scanner in computed tomography

Features

Versatile and adaptable for a wide variety of laboratory and research applications
Meets USP testing specifications

Documents

COA

SDS

Disclaimer: For laboratory research use only.

Propylene glycol (1, 2-Propanediol)