Specification

Full name	PARP1 (cleaved) rabbit polyclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit polyclonal
Applications	WB, IHC
Host	Rabbit
Clone type	rabbit polyclonal
Target Background	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Swissprot No	P09874
Gene Accession	NP_001609
WB Predicted band size	Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or PARP1(cleaved) antigen-treated (Neutralization experiment) using P102456(PARP1(cleaved) Antibody) at dilution 1/25
WB Positive control	P102456-WB-1-P
WB Recommended dilution	113 kDa
IHC predicted cell location	Predicted cell location: Cytoplasm, Nucleus
IHC positive control	Positive control: Human cervical cancer
IHC Recommed dilution	Recommended dilution: 25-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P102456-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or PARP1(cleaved) antigen-treated (Neutralization experiment) using P102456(PARP1(cleaved) Antibody) at dilution 1/25

PARP1 (cleaved) rabbit polyclonal antibody