Specification

Full name	NDUFS1 rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB, IHC, IF
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Swissprot No	P28331
Gene Accession	4719
WB Predicted band size
WB Positive control	P291009-WB-1-P
WB Recommended dilution	79 kDa
IHC predicted cell location	Predicted cell location: Cytoplasm
IHC positive control	Positive control: Human cholangiocarcinoma
IHC Recommed dilution	Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

P291009-WB-1-P

Immunohistochemical analysis of paraffin-embedded Human cholangiocarcinoma tissue using P291009(NDUFS1 Antibody) at dilution 1/50