Description

Recombinant Mouse LRP2 Protein Tag Free (MF-2025) is a recombinant mouse protein produced using a HEK293 mammalian expression system. The protein corresponds to the Gln26-Arg261 region and is supplied without an affinity tag for laboratory research applications requiring an untagged recombinant protein.

Obtaining a consistent and well-characterized recombinant protein is important for studies involving receptor-related proteins and protein interaction analysis. Recombinant Mouse LRP2 Protein Tag Free is supplied as a protein solution dissolved in sterile PBS buffer with defined purity and endotoxin specifications.

According to the provided product documentation, the protein is associated with LRP2-related nomenclature including Megalin and gp330, and is described with the listed synonyms Pancreatic Lipase-Related Protein 2, PL-RP2, Galactolipase, PNLIPRP2, and PLRP2.

This product is intended for research and manufacturing use only. It is not intended for diagnostic or therapeutic applications.

Specification

Product Name	Recombinant Mouse LRP2 Protein Tag Free
SKU	MF-2025
Protein Name	Mouse Low-Density Lipoprotein Receptor-Related Protein 2
Alternative Names	Pancreatic Lipase-Related Protein 2, PL-RP2, Galactolipase, PNLIPRP2, PLRP2, Megalin, gp330, Glycoprotein 330
Accession	A2ARV4
Source	HEK293
Expression System	HEK293 Mammalian Expression System
Protein Region	Gln26-Arg261
Tag	Tag Free
Predicted Molecular Mass	27 kDa

Formulation and Quality Information

Recombinant Mouse LRP2 Protein Tag Free is supplied as a protein solution dissolved in sterile PBS buffer. The solution can be diluted into other aqueous buffers.

Formulation	Protein solution in sterile PBS buffer
Purity	90% determined by SDS-PAGE
Endotoxin Level	<1.0 EU/μg protein determined by LAL method
Quality Analysis	SDS-PAGE analysis with Coomassie Blue staining
Activity	Activity testing in progress

Biological Information

According to the product documentation, Mouse LRP2 is associated with the low-density lipoprotein receptor family and is also described as Megalin or gp330. Full-length LRP2 is a type I transmembrane glycoprotein encoded by the Lrp2 gene and is highly expressed on the apical surface of absorptive epithelial cells, particularly in kidney proximal tubules.

LRP2 functions as a multiligand endocytic receptor and is involved in the uptake of diverse extracellular ligands, including lipoproteins, vitamin-binding proteins, hormones, and enzymes.

The provided product background information describes LRP2-related studies involving receptor-mediated endocytosis, cellular uptake mechanisms, ligand-receptor interactions, development, kidney function, and disease-related biological research.

Applications

Based on the biological information provided in the product documentation, Recombinant Mouse LRP2 Protein Tag Free is suitable for laboratory research involving LRP2-related biological studies, recombinant protein analysis, and protein interaction research.

LRP2-related protein research:
This recombinant mouse protein can be used in laboratory studies investigating LRP2-related biological mechanisms and protein characteristics.
Protein interaction studies:
The Tag Free recombinant LRP2 protein can support research workflows involving protein binding analysis and ligand-protein interaction studies.
Recombinant protein characterization:
The purified untagged mouse LRP2 protein can be incorporated into biochemical and recombinant protein analysis workflows.
Cellular uptake and receptor-related studies:
Based on the described function of LRP2 as a multiligand endocytic receptor, this protein can support research related to receptor-mediated biological mechanisms.

Storage and Shipping

Shipping Condition	Shipped with dry ice
Storage Condition	Store at -20°C to -70°C
Stability	12 months from date of receipt when stored as supplied
Storage Recommendation	Aliquot protein for optimal storage and minimize repeated freeze-thaw cycles

Centrifuge the vial prior to opening. Avoid repeated freeze-thaw cycles to maintain protein stability.

Documents

Data Sheet

FAQ

What is Recombinant Mouse LRP2 Protein Tag Free?

Recombinant Mouse LRP2 Protein Tag Free is a recombinant mouse protein corresponding to the Gln26-Arg261 region and produced using a HEK293 mammalian expression system without an affinity tag.

What are the alternative names of Mouse LRP2 protein?

According to the product documentation, the protein is described with the listed names Pancreatic Lipase-Related Protein 2, PL-RP2, Galactolipase, PNLIPRP2, PLRP2, as well as LRP2-related nomenclature including Megalin, gp330, and Glycoprotein 330.

What expression system is used for this recombinant mouse protein?

Recombinant Mouse LRP2 Protein Tag Free is produced using a HEK293 mammalian expression system.

What protein region is included in this recombinant Mouse LRP2 protein?

The recombinant protein corresponds to the Gln26-Arg261 region.

Does this product contain an affinity tag?

No. Recombinant Mouse LRP2 Protein Tag Free is supplied without an affinity tag.

What is the predicted molecular mass of Mouse LRP2 recombinant protein?

The predicted molecular mass of the recombinant mouse LRP2 protein is 27 kDa.

What is the purity of Recombinant Mouse LRP2 Protein Tag Free?

The purity is greater than 90% as determined by SDS-PAGE.

What applications can Recombinant Mouse LRP2 Protein Tag Free be used for?

This recombinant protein is suitable for laboratory research involving LRP2-related biological studies, recombinant protein analysis, and protein interaction research.

How should Mouse LRP2 recombinant protein be stored?

Store the protein at -20°C to -70°C and minimize repeated freeze-thaw cycles. Aliquoting is recommended for optimal storage.

Does this product have an endotoxin specification?

Yes. The endotoxin level is less than 1.0 EU per μg of protein as determined by the LAL method.