Specification

Full name	IRF3 (phospho-Ser386) rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]
Swissprot No	Q14653
Gene Accession	3661
WB Predicted band size	47 kDa
WB Positive control
WB Recommended dilution	500-2000
IHC predicted cell location	nan
IHC positive control	nan
IHC Recommed dilution	nan

Storage

-20°C, Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Avoid repeated freeze-thaw cycles.

P290761-WB-1-P