Specification

Full name	FCGR3A mouse monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	mouse monoclonal
Applications	WB
Host	Mouse
Clone type	mouse monoclonal
Target Background	This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swissprot No	P08637
Gene Accession	nan
WB Predicted band size	29 kDa
WB Positive control
WB Recommended dilution	1000-5000
IHC predicted cell location	nan
IHC positive control	nan
IHC Recommed dilution	nan

Storage

Ascitic fluid with 0.05% sodium azide and 40% glycerol

P113984-WB-1-P