Description

Chemical structure: macrolide
Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

Specification

Shipping Conditions	RT
UNSPSC Code	51101500
UNSPSC Category	Antibiotics and Antimycotics
CAS	[114-07-8]
Grade	USP
DG	No
Storage	18 to 25℃
Sterile	Yes

Application

Erythromycin has been used:

as a supplement for nutrient broth medium for culturing green fluorescent protein (GFP)- expressing E. coli
as a model drug to determine small intestinal (SMI) microtissue viability using the MTT assay{254
as an antibiotic to study the treatment strategies of chronic infections

Biochem/physiol Actions

Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex.

Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.

Documents

COA

SDS

Disclaimer: For laboratory research use only.