Specification

Full name	COX6C rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB, IHC
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]
Swissprot No	P09669
Gene Accession	1345
WB Predicted band size
WB Positive control	P290324-WB-1-P
WB Recommended dilution	9 kDa
IHC predicted cell location	Predicted cell location: Cytoplasm
IHC positive control	Positive control: Human colon cancer
IHC Recommed dilution	Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

P290324-WB-1-P

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P290324(COX6C Antibody) at dilution 1/50