{"product_id":"cfdna-special-d-cfdna-extraction-cell-free-dna-extraction","title":"cfDNA Special D cfDNA Extraction Cell Free DNA Extraction","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eCell-free DNA (cfDNA) refers to short, fragmented DNA molecules that are released into the bloodstream and other bodily fluids following cell death (apoptosis or necrosis). These fragments, typically ranging from 160 to 200 base pairs in length, provide a non-invasive window into the physiological and pathological state of the body.\u003cbr\u003eOur cell-free DNA (cfDNA) Extraction Magnetic Beads are engineered for the highly efficient and reliable isolation of short-fragment, low-concentration cfDNA from plasma, serum, and other liquid biopsies. Utilizing a specialized surface chemistry, these beads demonstrate superior binding affinity for dsDNA and ssDNA across a wide size range, ensuring maximum recovery of the critical 160-180 bp fraction that is rich in biological information. This technology is the cornerstone for robust and reproducible liquid biopsy workflows, enabling downstream applications in non-invasive prenatal testing (NIPT), cancer early detection, and transplant monitoring.\u003c\/p\u003e\n\u003ch2\u003eSpecification\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 90%;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cstrong\u003eParameter\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cstrong\u003eSpecification\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eAppearance\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eDark brown to black liquid, slight odor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e50 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eGrain Size\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e300 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eMagnetic Reaction Time\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u0026lt; 30 s\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eSediment Time\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u0026gt; 5 min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eMatrix\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eSilica magnetic beads\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eStorage Buffer\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eUltra pure water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eApplication\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eSerum\/plasma cell-free DNA\/RNA extraction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003ePackage\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e50 \/ 100 \/ 500 \/ 1000 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eShelf Life\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e24 months\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eStorage Condition\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e2–8°C, protected from light, do not freeze\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eCertifications\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eISO 9001, ISO 13485\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eHighlight\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eSpecial D cfDNA extraction; high-sensitivity cell-free DNA extraction; high-sensitivity cfDNA workflow\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eOptimized for Short Fragments: Superior recovery efficiency for short, fragmented cfDNA, minimizing the loss of critical biomarkers.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eHigh Sensitivity \u0026amp; Yield: Designed for maximum yield from low-input and low-concentration samples, which is essential for liquid biopsy applications.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eExceptional Purity: Effectively removes contaminants such as proteins, salts, and cellular genomic DNA, providing clean cfDNA ideal for sensitive downstream assays like NGS and dPCR.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRobust \u0026amp; Automation-Ready: Exhibits excellent chemical stability and dispersion, ensuring batch-to-batch consistency and seamless integration into automated, high-throughput nucleic acid extraction systems.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRapid Workflow: Streamlines the extraction process, reducing hands-on time and enabling quick turnaround from sample to analysis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis product is an indispensable tool for clinical researchers and diagnostic developers who require the highest standards of performance in their cfDNA analysis pipeline.\u003c\/p\u003e\n\u003ch2\u003eApplication\u003c\/h2\u003e\n\u003cp\u003eNucleic acid extraction and purification, suitable for serum\/plasma free DNA\/RNA\u003c\/p\u003e\n\u003cp\u003eThe analysis of cfDNA, particularly the subset derived from tumors known as circulating tumor DNA (ctDNA), has revolutionized diagnostic medicine. Its key applications encompass:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eNon-Invasive Prenatal Testing (NIPT): The detection of fetal cfDNA in maternal plasma allows for the early screening of chromosomal aneuploidies without any risk to the fetus.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLiquid Biopsy in Oncology: This is a transformative approach for cancer management. It enables early cancer detection, identification of targetable mutations for personalized therapy, real-time monitoring of treatment response, and early detection of minimal residual disease (MRD) and recurrence.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTransplant Monitoring: In organ transplant recipients, the quantification of donor-derived cfDNA serves as a highly sensitive, non-invasive biomarker for assessing graft rejection.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eResearch and Emerging Diagnostics: cfDNA analysis is being actively explored in other areas, including the study of autoimmune diseases and sepsis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAs a cornerstone of liquid biopsy, cfDNA analysis provides a powerful tool for precision medicine, offering critical insights that were previously inaccessible without invasive procedures.\u003c\/p\u003e","brand":"amerigoscientific","offers":[{"title":"50ml","offer_id":52458357227701,"sku":"NBF208-50ml","price":688.0,"currency_code":"USD","in_stock":true},{"title":"100ml","offer_id":52458357260469,"sku":"NBF208-100ml","price":1050.0,"currency_code":"USD","in_stock":true},{"title":"500ml","offer_id":52458357293237,"sku":"NBF208-500ml","price":4480.0,"currency_code":"USD","in_stock":true},{"title":"1000ml","offer_id":52458357326005,"sku":"NBF208-1000ml","price":8960.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/iShot_2025-12-01_12.42.00_8ab5d576-073f-4459-9af2-78c8866725f4.jpg?v=1777018350","url":"https:\/\/biofargo.com\/products\/cfdna-special-d-cfdna-extraction-cell-free-dna-extraction","provider":"Biofargo","version":"1.0","type":"link"}