Specification

Full name	CDKN1C rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB, IHC
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Swissprot No	P49918
Gene Accession	1028
WB Predicted band size
WB Positive control	P290281-WB-1-P
WB Recommended dilution	32 kDa
IHC predicted cell location	Predicted cell location: Nucleus
IHC positive control	Positive control: Human breast cancer
IHC Recommed dilution	Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

P290281-WB-1-P

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using P290281(CDKN1C Antibody) at dilution 1/50