Specification

Full name	Cdkn1b rabbit monoclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit monoclonal
Applications	WB, IHC
Host	Rabbit
Clone type	rabbit monoclonal
Target Background	Enables cyclin binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in several processes, including G1/S transition of mitotic cell cycle; heart development; and negative regulation of cardiac muscle tissue regeneration. Acts upstream of or within several processes, including negative regulation of cyclin-dependent protein serine/threonine kinase activity; negative regulation of epithelial cell proliferation involved in prostate gland development; and positive regulation of microtubule polymerization. Located in cytosol and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart and pericardium; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia; breast cancer; multiple endocrine neoplasia type 4; and myelodysplastic syndrome. Orthologous to human CDKN1B (cyclin dependent kinase inhibitor 1B). [provided by Alliance of Genome Resources, Apr 2022]
Swissprot No	P46414
Gene Accession	12576
WB Predicted band size	22 kDa
WB Positive control
WB Recommended dilution	500-2000
IHC predicted cell location	Predicted cell location: Nucleus
IHC positive control	Positive control: mouse lung
IHC Recommed dilution	Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P291706-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded mouse lung tissue using P291706(Cdkn1b Antibody) at dilution 1/50

Cdkn1b rabbit monoclonal antibody