Note:High-Frequency Co-Focused Ultrasound System,Tailored Shear Force,Temperature-Controlled Shearing Process,Non-Contact and Noise-Free Operation,Elimination of Manual Errors

Description

The Bowl Focused Ultrasonicators (BoFU 100) use a high-frequency co-focused ultrasound system to efficiently concentrate acoustic energy into the test sample. The BoFU system, by adjusting the operation mode of the ultrasonic generator, provides shear force that meets the needs of genomics and proteomics research. The entire shearing process is temperature-controllable, has no sample contact, and generates no noise. BoFU eliminates errors introduced by manual operation, improves repeatability, enhances efficiency, and provides standardized results.

Instrument Parameters

Parameter/Instrument Model	BoFU-100
Dimensions	390mm400mm330mm
Tank Volume	160ml
Weight	15kg
Maximum Power	100w
Sample Position	1
Sample Volume	25ul-2ml
Preset Parameters	5
Temperature Control	4℃-25℃ ±0.5℃
Mode	Single Processing
Cooling Method	Built-in
Waste Liquid Storage	None
Batch Input	None
Input Operation	Touch Screen Panel

Introduction to Technical Principles

The BoFU ultrasonic system utilizes advanced co-focusing technology to precisely focus high-frequency, short-wavelength sound waves onto the sample, resulting in a highly controllable sample preparation process. High-frequency focused sound waves create a localized high-pressure zone in the target area, generating a controlled pressure flux and acoustic field. Under high-intensity 'dosing,' cavitation bubbles are formed, which shear the sample.

Technological Advancement

Traditional probe-type or tank-type ultrasonic generators use low-frequency, divergent sound wave energy within the range of human hearing. Unfocused sound wave energy dissipates rapidly and converts into thermal energy (the first law of thermodynamics) during this process. The quick dissipation of low-frequency sound energy leads to reduced efficiency, requiring a large amount of sound energy to achieve the desired effects. The excess energy produces heat that can cause significant damage to the sample's structure.

Probe-type ultrasonic generators come into direct contact with the sample, allowing for more energy to be concentrated on the sample compared to tank-type ultrasonic generators. However, direct contact with small sample volumes can lead to sample cross-contamination and tip corrosion, reducing ultrasonic efficiency. Tank-type ultrasonic generators separate the sample from the energy source but require more energy input than probe-type ultrasonic generators, causing greater heat damage to the samples.

Document

Comparison between Biofargo and Covaris by Labchip

INTRO OF BOFU

Tech Comparison between Biofargo and Covaris

Operate Video

Video Bofu 100

BoFU Focused Ultrasonicator-Noise Free-Standardized Results-BoFU-100