Specification

Full name	BCL2L1 rabbit polyclonal antibody
Alternative names	50 μl/100 μl
Reactivity	rabbit polyclonal
Applications	WB
Host	Rabbit
Clone type	rabbit polyclonal
Target Background	The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Swissprot No	Q07817
Gene Accession	BC019307
WB Predicted band size
WB Positive control	P107825-WB-1-P
WB Recommended dilution	26 kDa
IHC predicted cell location
IHC positive control
IHC Recommed dilution

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

P107825-WB-1-P