Product Profile

Key Feature

Gene Symbol	CD68
Gene Synonyms	GP110 LAMP4 SCARD1
Gene Full Name	CD68 molecule
Gene Summary	This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Molecular Weight(MW)	37 kDa（Observed:52 kDa）
Source	Rabbit
Cellular Localization	Cell membrane and Endosome membrane. Lysosome membrane.

Form	Liquid
Storage Instructions	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.

Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.