{"title":"Recombinant Proteins","description":"\u003cp\u003eRecombinant proteins are proteins created through genetic engineering techniques. They have become essential in biomedical biotechnology, serving both as research tools and as treatments for a range of diseases.\u003c\/p\u003e","products":[{"product_id":"ok432","title":"NK Cell Activator-OK432","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:920px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eOK432 is an immunomodulatory agent produced through the lyophilization of Group A Streptococcus pyogenes.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIt activates neutrophils, enabling them to effectively kill tumor cells pretreated with IFN-γ or TNF-α. This cytotoxic effect is mediated by the interaction between CD11b\/CD18 on neutrophils and ICAM-1 expressed on tumor cells.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eFurthermore, OK432 stimulates monocytes to enhance their tumoricidal activity against autologous cancer cells.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIn lymphocytes, OK432 induces lymphokine-activated killer (LAK) cell activity, which demonstrates potent cytotoxicity even against NK-resistant tumor cells.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eDue to its immunomodulatory and antitumor properties, OK432 is suitable for the development and production of cell-based therapeutics.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eOK432 is standardized in Klinische Einheit (KE), a clinical unit of biological activity. The potency is defined such that 1 KE is equivalent to 0.1 mg of the lyophilized bacterial product.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:20%;\"\u003eProduct\u003c\/th\u003e\n \u003cth style=\"width:30%;\"\u003eParameter\u003c\/th\u003e\n \u003cth style=\"width:30%;\"\u003eSpecification\u003c\/th\u003e\n \u003cth class=\"center\" style=\"width:20%;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003c!-- GMP-TL107-0100 --\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"6\" class=\"center\"\u003eGMP-TL107-0100\u003c\/td\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eVisible Particle\u003c\/td\u003e\n \u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMoisture\u003c\/td\u003e\n \u003ctd\u003e≤4.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e1.7%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003epH\u003c\/td\u003e\n \u003ctd\u003e6.5~7.5\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e7.2\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMycoplasma\u003c\/td\u003e\n \u003ctd\u003eShould be negative\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003c!-- GMP-TL107-0500 --\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"10\" class=\"center\"\u003eGMP-TL107-0500\u003c\/td\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eVisible Particle\u003c\/td\u003e\n \u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMoisture\u003c\/td\u003e\n \u003ctd\u003e≤3.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e1.3%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eAbnormal Toxicity\u003c\/td\u003e\n \u003ctd\u003eShould comply with the regulations\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\"\u003eConcentration Determination\u003c\/td\u003e\n \u003ctd\u003eThe difference between bottles shall not exceed ±15%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e1.1%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eThe average content shall not exceed 90% - 110% of the labeled amount\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e97.6%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eTumor Suppression Test\u003c\/td\u003e\n \u003ctd\u003eThe life extension rate should not be less than 50%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e91%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eRelative Content Determination of Penicillin-thiazole Protein\u003c\/td\u003e\n \u003ctd\u003eIt shall be less than 0.03%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eNK Cell Activity Assay\u003c\/td\u003e\n \u003ctd\u003eCytotoxic index T-C by ≥10%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e21.0%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eLyophilized Bacterial Immunomodulator\u003c\/strong\u003e\n \u003cp\u003eOK432 is produced through lyophilization of Group A Streptococcus pyogenes and supplied as a white, fluffy lyophilized powder.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eStandardized Biological Potency (KE Unit)\u003c\/strong\u003e\n \u003cp\u003eActivity is standardized in Klinische Einheit (KE), where 1 KE corresponds to 0.1 mg of the lyophilized bacterial product.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eNK Cell Activation Activity\u003c\/strong\u003e\n \u003cp\u003eOK432-activated NK cells exhibit a cytotoxicity index (T–C) ≥15%, with batch result reaching 21.0% in NK cell activity assay.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eQuality-Controlled Safety Profile\u003c\/strong\u003e\n \u003cp\u003eComplies with specifications for appearance, moisture (1.7% \/ 1.3%), pH (6.5–7.5 range), sterility (no growth), mycoplasma negative, and abnormal toxicity testing (where applicable).\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eNeutrophil Tumor Cytotoxicity\u003c\/h4\u003e\n \u003cp\u003eActivates neutrophils to kill tumor cells pretreated with IFN-γ or TNF-α via CD11b\/CD18–ICAM-1 interaction.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eMonocyte Antitumor Activation\u003c\/h4\u003e\n \u003cp\u003eStimulates monocytes to enhance tumoricidal activity against autologous cancer cells.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eLAK Cell Induction\u003c\/h4\u003e\n \u003cp\u003eInduces lymphokine-activated killer (LAK) cell activity in lymphocytes, demonstrating cytotoxicity against NK-resistant tumor cells.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eNK Cell Function Studies\u003c\/h4\u003e\n \u003cp\u003eCan be used to activate NK cells for cytotoxicity enhancement in in vitro immune function studies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left:20px; margin:10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Stable for 24 months at 2–8°C in the original.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eReconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4) maintaining final concentration ≥100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-caution\"\u003e\n \u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-OK432.pdf?v=1772505194\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL107 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-OK432.pdf?v=1772505195\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL107 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-PrDZ2405007-GMP-TL107-0100.pdf?v=1772505194\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL107-0100 COA\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-SPrDZ2509002-GMP-TL107-0500.pdf?v=1772505194\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL107-0500 COA\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"100μg","offer_id":43214503542965,"sku":"GMP-TL107-0100","price":190.0,"currency_code":"USD","in_stock":true},{"title":"500μg","offer_id":43214503575733,"sku":"GMP-TL107-0500","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL107-0100.png?v=1772505175"},{"product_id":"recombinant-human-4-1bb-ligand-protein","title":"Recombinant Human 4-1BB Ligand Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:920px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\n \/* =========================\n Data Figures (image card)\n ========================== *\/\n .biofargo-figure-card{\n text-align:center;\n margin-top:20px;\n border:1px solid #eee;\n padding:15px;\n border-radius:8px;\n background:#fff;\n }\n .biofargo-figure-card img{\n max-width:100%;\n height:auto;\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eThe recombinant human 4-1BB Ligand-Fc fusion protein is a functional dimeric immunomodulator produced in HEK-293 expression systems, featuring a C-terminal human IgG1 Fc domain to enhance structural stability and receptor clustering efficiency.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eAs a TNF superfamily member (TNFSF9\/CD137L), it activates NF-κB and MAPK signaling pathways through binding to 4-1BB (CD137\/TNFRSF9) on T cells, delivering critical costimulatory signals that drive T-cell proliferation, IFN-γ\/IL-2 secretion, and expansion of effector memory T-cell subsets, while suppressing activation-induced cell death (AICD) via upregulation of Bcl-xL.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIn cell therapy applications, this fusion protein serves as a pivotal component in ex vivo expansion systems, mimicking antigen-presenting cell (APC) costimulatory signals to significantly enhance CAR-T cell clonal expansion and persistence.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIt synergizes with CD28 signaling to optimize T-cell metabolic reprogramming and boost effector functions of tumor-infiltrating lymphocytes (TILs), providing functional support for solid tumor immunotherapy.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eThe Fc domain design not only extends serum half-life but also ensures high-affinity trimeric engagement with 4-1BB receptors through spatial conformation optimization, enabling sustained signal activation.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:33.33%;\"\u003eParameter\u003c\/th\u003e\n \u003cth style=\"width:33.33%;\"\u003eSpecification\u003c\/th\u003e\n \u003cth class=\"center\" style=\"width:33.33%;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eIdentity\u003c\/td\u003e\n \u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eVisible Particle\u003c\/td\u003e\n \u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMoisture\u003c\/td\u003e\n \u003ctd\u003e≤4.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e1.4%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003epH\u003c\/td\u003e\n \u003ctd\u003e6.5~7.5\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e7.3\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;90.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMycoplasma\u003c\/td\u003e\n \u003ctd\u003eShould be negative\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eEach hole is covered by 100μL Recombinant human 4-1BB (His tag) protein with a concentration of 1μg\/mL; the ability of 4-1BB Ligand (Fc tag) to bind to 4-1BB (His tag) protein was determined by ELISA, ED50 ≤ 50ng\/mL\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e20.53ng\/mL\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eMammalian-Expressed Fc Fusion Design\u003c\/strong\u003e\n \u003cp\u003eRecombinant human 4-1BB Ligand (Ala50–Glu254) expressed in HEK293 cells with a C-terminal human IgG1 Fc fragment, forming a dimeric fusion protein with a predicted molecular weight of 51.0 kDa.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity and Identity Verification\u003c\/strong\u003e\n \u003cp\u003ePurity \u0026gt;90% as determined by SDS-PAGE, with electrophoretic bands consistent with the expected molecular weight and no visible particles detected.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eLow Endotoxin and Sterility Assurance\u003c\/strong\u003e\n \u003cp\u003eEndotoxin level \u0026lt;0.1 EU per 1 µg protein (LAL assay), mycoplasma negative, and sterility confirmed with no microbial growth.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eValidated 4-1BB Binding Activity\u003c\/strong\u003e\n \u003cp\u003eBinds immobilized recombinant human 4-1BB\/His Tag (1 µg\/mL, 100 µL\/well) in functional ELISA with ED₅₀ ≤50 ng\/mL (measured 20.53 ng\/mL).\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eT Cell Costimulatory Activation\u003c\/h4\u003e\n \u003cp\u003eEngages 4-1BB (CD137\/TNFRSF9) on T cells to activate NF-κB and MAPK pathways, promoting T-cell proliferation and IFN-γ\/IL-2 secretion.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eCAR-T Ex Vivo Expansion Support\u003c\/h4\u003e\n \u003cp\u003eFunctions as a costimulatory component in ex vivo expansion systems to enhance CAR-T cell clonal expansion and persistence.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eEffector Memory T Cell Modulation\u003c\/h4\u003e\n \u003cp\u003eDrives expansion of effector memory T-cell subsets and suppresses activation-induced cell death via Bcl-xL upregulation.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eTIL Functional Enhancement Research\u003c\/h4\u003e\n \u003cp\u003eSynergizes with CD28 signaling to optimize T-cell metabolic reprogramming and enhance effector functions of tumor-infiltrating lymphocytes.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left:20px; margin:10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eReconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4), maintaining final concentration ≥100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-caution\"\u003e\n \u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_4-1BB_Ligand_Protein.pdf?v=1772504508\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL695 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_4-1BB_Ligand_Protein.pdf?v=1772504508\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL695 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2406008-GMP-TL695-0050.pdf?v=1772504508\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL695 COA\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214476476597,"sku":"GMP-TL695-0050","price":190.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214476509365,"sku":"GMP-TL695-0100","price":310.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL695-0050.png?v=1772504583"},{"product_id":"recombinant-human-epo-protein","title":"Recombinant Human EPO Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:900px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\u003c\/style\u003e\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\u003c!-- Description --\u003e\n\u003cdiv style=\"margin-top: 0;\" class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eDescription \u003c\/h2\u003e\n\u003cdiv class=\"biofargo-card\"\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eRecombinant human erythropoietin (EPO) is a glycosylated cytokine essential for erythropoiesis, specifically promoting the proliferation and differentiation of erythroid progenitor cells (CFU-E) into mature erythrocytes.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eWhile renal production maintains physiological EPO levels in adults, hepatic synthesis predominates during fetal and neonatal development.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eBeyond its canonical role in hematopoiesis, EPO exhibits pleiotropic bioactivities, including angiogenic stimulation via vascular smooth muscle cell proliferation, neuroprotective effects under hypoxic conditions, and modulation of B-cell function.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003eThe recombinant protein retains native conformational integrity, ensuring targeted activation of the EPO receptor (EPOR) to orchestrate tissue-specific responses without off-target interactions, making it invaluable for therapeutic applications in anemia treatment and regenerative medicine.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Specifications --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrap\"\u003e\n\u003ctable class=\"biofargo-table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 25%;\"\u003eSpecification\u003c\/th\u003e\n\u003cth style=\"width: 35%;\"\u003eAcceptance Criteria\u003c\/th\u003e\n\u003cth style=\"width: 20%;\" class=\"center\"\u003eTL-636-0050\u003c\/th\u003e\n\u003cth style=\"width: 20%;\" class=\"center\"\u003eTL-636-0100\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAppearance\u003c\/td\u003e\n\u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentity\u003c\/td\u003e\n\u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVisible Particle\u003c\/td\u003e\n\u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMoisture\u003c\/td\u003e\n\u003ctd\u003e≤4.0%\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e2.0%\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e2.9%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003epH\u003c\/td\u003e\n\u003ctd\u003e6.5~7.5\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e7.3\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e7.3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;90% \/ SDS-PAGE\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMycoplasma\u003c\/td\u003e\n\u003ctd\u003eShould be negative\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSterility\u003c\/td\u003e\n\u003ctd\u003eNo growth\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiological Activity\u003c\/td\u003e\n\u003ctd\u003eCell proliferation assay with TF-1 cells, specific activity ≥1×10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e3.08×10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e—\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Features --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n\u003cul class=\"biofargo-checklist\"\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eGlycosylated, Mammalian-Derived EPO\u003c\/strong\u003e\n\u003cp\u003eHEK293 expression preserves native glycosylation and EPOR-specific signaling fidelity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eValidated High Biological Activity\u003c\/strong\u003e\n\u003cp\u003eDemonstrated potency in TF-1 cell proliferation assay (≥1.0 × 10⁶ IU\/mg).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity with Stringent QC\u003c\/strong\u003e\n\u003cp\u003e90% purity by SDS-PAGE with confirmed sterility, mycoplasma negativity, and low endotoxin.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eConsistent Lot-to-Lot Performance\u003c\/strong\u003e\n\u003cp\u003eControlled moisture, pH, and activity ensure reproducibility in hematopoietic research workflows.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!-- Applications --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-grid\"\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eErythropoiesis Research\u003c\/h4\u003e\n\u003cp\u003ePromotes proliferation and differentiation of erythroid progenitors (CFU-E).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eT Cell-Related Studies\u003c\/h4\u003e\n\u003cp\u003eApplied as a functional cytokine component in immune cell research systems.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eCIK Cell Research\u003c\/h4\u003e\n\u003cp\u003eUsed in cytokine-induced killer (CIK) cell culture and functional modulation studies.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eRegenerative \u0026amp; Angiogenesis Research\u003c\/h4\u003e\n\u003cp\u003eExplored for non-hematopoietic roles including angiogenesis and tissue protection under hypoxia.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Stability \u0026 Storage --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px; margin: 10px 0 0 0;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized powder: Stable for 12 months at −80 °C or 6 months at −20 °C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eReconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4), maintaining a final concentration ≥100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 0;\"\u003eHandling: Aliquot to avoid repeated freeze–thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!-- Cautions (Universal) --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-caution\"\u003e\n\u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Documents --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-docs\"\u003e\n\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_EPO_Protein.pdf?v=1772435758\" class=\"biofargo-btn primary\" target=\"_blank\"\u003e📄 TL-636 Data Sheet\u003c\/a\u003e \u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_EPO_Protein.pdf?v=1772435759\" class=\"biofargo-btn outline\" target=\"_blank\"\u003e📄 TL-636 SDS\u003c\/a\u003e \u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2410007-TL-636-0050.pdf?v=1772435758\" class=\"biofargo-btn outline\" target=\"_blank\"\u003e📄 TL-636-0050 COA\u003c\/a\u003e \u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2306009-TL-636-0100.pdf?v=1772435758\" class=\"biofargo-btn outline\" target=\"_blank\"\u003e📄 TL-636-0100 COA\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214480375989,"sku":"TL-636-0050","price":220.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214480408757,"sku":"TL-636-0100","price":300.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Recombinant_Human_EPO_Protein.jpg?v=1775112623"},{"product_id":"recombinant-human-fibronectin-fn-protein","title":"Recombinant Human Fibronectin (FN) Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eFibronectin (FN) is a dimeric glycoprotein with an approximate molecular weight of 230–250 kDa, covalently linked via C-terminal disulfide bonds. Each monomer comprises 12 type I, 2 type II, and 15–17 type III functional domains that orchestrate multidimensional interactions with cell-surface integrins (α5β1\/αvβ3) and extracellular matrix components (collagen\/heparin) through specific RGD (Arg-Gly-Asp) and CS1 sequences.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eFunctionally, it participates in coagulation cascades and host defense as a soluble plasma protein, or serves as a cross-linked polymeric core component in tissue engineering scaffolds, regulating cell adhesion, migration, and differentiation via mechanotransduction.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eIn cell therapy applications, its recombinant fragment (containing Cell-Binding Domain\/CBD, Heparin-Binding Domain\/HBD, and CS1 sites) acts as a viral transduction enhancer substrate, leveraging spatial co-localization principles to improve lentiviral vector anchoring efficiency in CAR-T production, boosting primary T-cell transduction rates by 3- to 5-fold.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: left;\"\u003eWithin 3D mesenchymal stem cell (MSC) culture systems, it activates the FAK-PI3K-Akt signaling axis to preserve stemness and guide neuro\/vascular lineage differentiation, significantly enhancing the in vivo survival of tissue-engineered grafts.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eCold-insoluble globulin\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P02751-1\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003ePro1270–Ser1546 \u0026amp; Ala1721–Thr2016\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eN-terminal His tag\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003e\u003cem\u003eE. coli\u003c\/em\u003e\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e68.0 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 90% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003ePromotes adhesion of human induced pluripotent stem (hiPS) cells with an ED\u003csub\u003e50\u003c\/sub\u003e ≤ 3.2 μg\/mL\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLiquid formulation in sterile PBS (pH 7.4), typically supplemented with human serum albumin (HSA) as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0; margin: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product is purified using advanced chromatographic techniques, achieving a purity level of over 95%, ensuring accurate and reproducible experimental outcomes.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Demonstrated through multiple activity assays, this product effectively supports cell adhesion, migration, and proliferation, making it suitable for various cell culture applications.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Produced under stringent quality control measures to ensure consistency between batches, minimizing variability and enhancing the reliability of research results.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Manufactured without the use of animal-derived components, adhering to animal-free standards and expanding its applicability for diverse research needs.\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Adhesion Studies\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate the role of fibronectin in cell adhesion and migration, contributing to a deeper understanding of cell-matrix interactions.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eTissue Engineering\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUtilize fibronectin in tissue scaffolds and matrices to promote cell attachment and tissue regeneration, advancing the development of regenerative therapies.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eWound Healing Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExplore the impact of fibronectin on wound healing processes, including tissue repair and remodeling, providing insights into potential therapeutic approaches.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCancer Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the role of fibronectin in tumor cell behavior and metastasis, offering valuable information for cancer research and treatment strategies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp;  Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Liquid: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Reconstitution: N\/A \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0;\"\u003e√ Handling: Aliquot to avoid repeated freeze-thaw cycles. \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Instructions for Use --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment prior to use.\u003cbr\u003e\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003ePrepare and dilute the solution according to experimental requirements for accurate and reproducible results.\u003cbr\u003e\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: left;\"\u003eAvoid mixing with other similar products to prevent cross-reactivity and interference.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocument\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: #fff; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_Fibronectin_FN_Protein.pdf?v=1772517662\" target=\"_blank\"\u003e📄 TL-903 Data Sheet\u003c\/a\u003e\n\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_Fibronectin_FN_Protein.pdf?v=1772517662\"\u003e📄 TL-903 SDS\u003c\/a\u003e\n\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-SPr2507002-GMP-TL903-0250.pdf?v=1772517662\" target=\"_blank\"\u003e📄 TL-903 COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214480834741,"sku":"GMP-TL903-0050","price":380.0,"currency_code":"USD","in_stock":true},{"title":"250μg","offer_id":43214480867509,"sku":"GMP-TL903-0250","price":410.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL903-0050.jpg?v=1772421165"},{"product_id":"hla-a-02-01","title":"HLA-A*02:01","description":"\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eSerological Name:\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eA2\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003ePeptide Load:\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eEndogenous\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eSize:\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003e30.0 µg\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eModification:\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eUnmodified\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eVolume:\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003e30.0 µl\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eConjugate:\u003c\/td\u003e\n\u003ctd style=\"width: 25%; text-align: center;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"short-description\"\u003e\u003c\/div\u003e\n\u003cp data-mce-fragment=\"1\" class=\"short-description\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" class=\"short-description\"\u003eRecombinant, truncated Class I soluble Human Leukocyte Antigen (sHLA), naturally folded and glycosylated, loaded with endogenous peptides.\u003c\/p\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-attributes\"\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-attribute\"\u003e\n\u003ch3 data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003clabel data-mce-fragment=\"1\" class=\"catalog_list-item__attribute-head\"\u003eALLELE NAME\u003c\/label\u003e\u003c\/h3\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eA*02:01, B2m\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-attribute\"\u003e\n\u003ch3 data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003clabel data-mce-fragment=\"1\" class=\"catalog_list-item__attribute-head\"\u003eSEROLOGICAL NAME\u003c\/label\u003e\u003c\/h3\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eA2\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-attribute\"\u003e\n\u003ch3 data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003clabel data-mce-fragment=\"1\" class=\"catalog_list-item__attribute-head\"\u003eALLELE FREQUENCY - WORLDWIDE POPULATION\u003c\/label\u003e\u003c\/h3\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e12.0%\/–\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-attribute\"\u003e\n\u003ch3 data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003clabel data-mce-fragment=\"1\" class=\"catalog_list-item__attribute-head\"\u003eALTERNATIVE NAMES\u003c\/label\u003e\u003c\/h3\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eA*0201, A0201, A*02, A02, A2\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-attribute\"\u003e\n\u003ch3 data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003clabel data-mce-fragment=\"1\" class=\"catalog_list-item__attribute-head\"\u003eRECOMMENDED ANTIBODIES\u003c\/label\u003e\u003c\/h3\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eW6\/32, Anti-B2m\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-attribute\"\u003e\n\u003ch3 data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003clabel data-mce-fragment=\"1\" class=\"catalog_list-item__attribute-head\"\u003eAPPLICATIONS\u003c\/label\u003e\u003c\/h3\u003e\n\u003cp data-mce-fragment=\"1\" class=\"eq_height\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHLA Sandwich ELISAs, HLA Direct ELISAs, HLA-Sera Antibody Assays, HLA Controls in ELISA Assays, HLA Assay Standards, HLA Blocking Assays, HLA Neutralizing Assays, HLA Competition Assays, HLA Bead Assays, HLA Immunization Procedures\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ctable border=\"1\" style=\"border-collapse: collapse; width: 100%; height: 234px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eConjugate\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eComplexity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eMonomer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eHLA Species\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eHost Cell Line Species\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eClone Designation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eOB11\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eTail Specification\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eVLDL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eProtein Format\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eRecombinant, truncated, soluble, non-modified, non-labeled, endogenously loaded\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eStorage Temperature\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003e4˚C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003e1000.0 µg\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003ePBS\/0.02% Sodium Azide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003epH\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003e7.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eGrade\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eResearch Use Only [RUO]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eAuthentication Method\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eSequence Based Typing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003e\u003c\/h2\u003e\n\u003ch2\u003eSequences\u003c\/h2\u003e\n\u003ch3\u003eALPHA CHAIN SEQUENCE\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eGSHSMRYFFT SVSRPGRGEP RFIAVGYVDD TQFVRFDSDA ASQRMEPRAP WIEQEGPEYW DGETRKVKAH SQTHRVDLGT LRGYYNQSEA GSHTVQRMYG CDVGSDWRFL RGYHQYAYDG KDYIALKEDL RSWTAADMAA QTTKHKWEAA HVAEQLRAYL EGTCVEWLRR YLENGKETLQ RTDAPKTHMT HHAVSDHEAT LRCWALSFYP AEITLTWQRD GEDQTQDTEL VETRPAGDGT FQKWAAVVVP SGQEQRYTCH VQHEGLPKPL TLRSVVSTDD DLA\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eBETA CHAIN SEQUENCE\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eIQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cbr\u003e\u003c\/h2\u003e","brand":"hlaprotein","offers":[{"title":"Default Title","offer_id":43193412878517,"sku":"A0201","price":773.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/a0201_hla1_3d_r_2.png?v=1732874223"},{"product_id":"recombinant-human-flt3-ligand-protein","title":"Recombinant Human FLT3 Ligand Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eThe recombinant human Fms-Related Tyrosine Kinase 3 Ligand (FLT3L\/Flt3 Ligand) is a high-purity, four-helical bundle cytokine produced in HEK-293 expression systems, typically existing as a noncovalently-linked dimer.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eAs a pivotal cytokine in the hematopoietic system, FLT3L specifically binds to its receptor FLT3 (CD135\/FLK-2\/STK-1, a class III receptor tyrosine kinase), activating downstream signaling pathways including RAS-MAPK and PI3K-AKT-MTOR.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eThis regulates the proliferation, differentiation, and survival of hematopoietic progenitor cells and dendritic cells (DCs), and induces the mobilization of hematopoietic progenitors and stem cells in vivo.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eFLT3L critically governs DC development, being particularly essential for plasmacytoid DCs (pDCs), CD8-positive classical DCs (cDCs), and their CD103-positive tissue-resident counterparts.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eBy synergizing with various growth factors, FLT3L stimulates the expansion and differentiation of diverse blood cell progenitors and enhances anti-tumor immune responses by potentiating the function of DCs, which provide the key link between innate and adaptive immunity by recognizing pathogens and priming specific immune responses, making it highly valuable for applications in cancer immunotherapy and hematopoietic stem cell transplantation.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: left;\"\u003eIts native dimeric configuration preserves full bioactivity.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eFms-related tyrosine kinase 3 ligand, FLT3LG, FL, FLT3L, SL cytokine\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P49771-1\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003eThr27–Ala181\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e18.4 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 90% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eMeasured by OCI-AML5 cell proliferation assay, corresponding to a specific activity of ≥ 5.0 × 10\u003csup\u003e5\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile PBS (pH 7.4), typically supplemented with 6% mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0; margin: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product is purified through advanced chromatographic techniques, achieving a purity level of over 95%, ensuring accurate and consistent experimental results.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Demonstrated through multiple activity assays, this protein effectively stimulates FLT3 receptor-positive cells, supporting research on cell proliferation and differentiation.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Produced with stringent quality control measures to ensure high consistency between batches, reducing variability and enhancing the reliability of research outcomes.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Manufactured without the use of animal-derived components, adhering to animal-free standards and broadening its application scope for diverse research needs.\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the role of FLT3L in the growth and differentiation of hematopoietic stem cells and progenitor cells, providing insights into blood cell development and potential treatments for hematological disorders.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate the effects of FLT3L on immune cell development and function, exploring its potential in immunotherapy and immune system modulation.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCancer Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExamine the role of FLT3L in cancer cell biology, including tumor growth and immune cell interactions, contributing to the development of novel cancer therapies.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUtilize FLT3L to support the expansion and maintenance of stem cells in culture, advancing research in regenerative medicine and cell-based therapies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√Lyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√Reconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥ 100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0;\"\u003e√Handling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Instructions for Use --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003e1.Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment prior to use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003e2.Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: left;\"\u003e3.Avoid mixing with other similar products to prevent cross-reactivity and interference.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocument\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_FLT3_Ligand_Protein.pdf?v=1772517449\" target=\"_blank\"\u003e📄 GMP-TL505 Data Sheet\u003c\/a\u003e\n \n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_FLT3_Ligand_Protein.pdf?v=1772517449\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL505 SDS\u003c\/a\u003e\n \n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2408002-GMP-TL505-0050.pdf?v=1772517449\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL505 COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214482014389,"sku":"GMP-TL505-0050","price":380.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL505-0050.png?v=1772421759"},{"product_id":"recombinant-human-gm-csf-protein","title":"Recombinant Human GM-CSF Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003c!-- Description --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eGranulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) is a pivotal glycosylated cytokine functioning extracellularly as a homodimer. Its core function is to stimulate the proliferation and differentiation of hematopoietic stem\/progenitor cells into granulocytes and monocytes (which mature into macrophages and dendritic cells).\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eLeveraging this, GM-CSF finds extensive application in cell and gene therapy. In cell therapy, it is a critical factor for the in vitro expansion of immune cells (e.g., dendritic cells for DC vaccines) and acts as an immune modulator in vivo to activate DCs and T cells, enhancing anti-tumor immunity.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eIn gene therapy, its encoding gene (located in the chromosome 5q31 region) serves as a potential target, or therapeutic GM-CSF can be delivered via vectors for localized and sustained expression.\u003c\/p\u003e\n\u003cp style=\"margin: 0; text-align: left;\"\u003eRecombinantly produced GM-CSF protein provides an essential tool for these applications, with its potential dual immunomodulatory effects requiring careful evaluation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!-- Specifications --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\n\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #0056b3; color: #fff;\"\u003e\n\u003cth colspan=\"3\" style=\"padding: 12px; text-align: left;\"\u003eProduct Details\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 30%; font-weight: bold; background-color: #f8f9fa;\"\u003eParameter\u003c\/td\u003e\n\u003ctd style=\"width: 35%; font-weight: bold; text-align: center;\"\u003eRUO Grade\u003c\/td\u003e\n\u003ctd style=\"width: 35%; font-weight: bold; text-align: center;\"\u003eGMP Grade\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eCatalog Number\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eTL-302-0010\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eGMP-TL302-0100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd\u003eCSF2, MGC131935\u003c\/td\u003e\n\u003ctd\u003eColony-stimulating factor (CSF), Molgramostin, Sargramostim, CSF2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eUniProt P04141\u003c\/td\u003e\n\u003ctd\u003eUniProt P04141\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n\u003ctd\u003eAla18–Glu144\u003c\/td\u003e\n\u003ctd\u003eAla18–Glu144\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n\u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n\u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eHEK293 cells\u003c\/td\u003e\n\u003ctd\u003eHEK293 cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd\u003e19.3 kDa\u003c\/td\u003e\n\u003ctd\u003e15.3 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;90% (SDS-PAGE)\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;95% (SDS-PAGE)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.1 EU\/µg\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.1 EU\/µg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n\u003ctd\u003eTF-1 cell proliferation assay,\u003cbr\u003e≥ 5.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003ctd\u003eTF-1 cell proliferation assay,\u003cbr\u003e≥ 5.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized from PBS (pH 7.4), 6% mannitol\u003c\/td\u003e\n\u003ctd\u003eLyophilized from PBS (pH 7.4), 6% mannitol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c!-- Features --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0; margin: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Purified using advanced chromatographic techniques, this product achieves a purity level of over 95%, ensuring high reliability and reproducibility of experimental results.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Validated through multiple activity assays, this GM-CSF protein effectively stimulates target cells, supporting a variety of research applications related to immune cell function and hematopoiesis.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Produced with strict quality control measures to ensure consistent quality between batches, minimizing variability and enhancing the reliability of research outcomes.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Manufactured without animal-derived components, complying with animal-free standards and broadening its applicability for various research needs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- Applications --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the role of GM-CSF in the regulation of blood cell production, including granulocytes and macrophages, providing insights into hematopoietic disorders and therapies.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate GM-CSF’s effects on immune cell development and activation, contributing to a deeper understanding of immune responses and potential therapeutic applications.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCancer Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExamine the role of GM-CSF in tumor microenvironments and its impact on immune cell function, offering insights into cancer immunotherapy and treatment strategies.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Therapy\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUtilize GM-CSF to enhance the function and expansion of immune cells in cell-based therapies, advancing research in regenerative medicine and immunotherapy.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Stability \u0026 Storage --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0; margin-top: 10px;\"\u003e\n\u003ch3 style=\"margin: 0 0 10px 0; font-size: 16px; color: #333;\"\u003eRUO\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli style=\"text-align: left;\"\u003e\n\u003cp\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"text-align: left;\"\u003e\n\u003cp\u003eReconstitution: Dissolve contents in 200 µL sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration about 50 µg\/mL.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"text-align: left;\"\u003e\n\u003cp\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0; margin-top: 15px;\"\u003e\n\u003ch3 style=\"margin: 0 0 10px 0; font-size: 16px; color: #333;\"\u003eGMP\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli style=\"text-align: left;\"\u003e\n\u003cp\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"text-align: left;\"\u003e\n\u003cp\u003eReconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥ 100 µg\/mL to prevent adsorption. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"text-align: left;\"\u003e\n\u003cp\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!-- Cautions (Universal) --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!-- Documents --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocument\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_GM-CSF_Protein.pdf?v=1772517199\" style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: #fff; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 GMP\/RUO TL302 SDS\u003c\/a\u003e \n \n\n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_GM-CSF_Protein-GMP.pdf?v=1772517199\" type=\"application\/pdf\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 GMP-TL302 Data Sheet\u003c\/a\u003e\n \n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_GM-CSF_Protein-RUO.pdf?v=1772517199\" type=\"application\/pdf\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 TL-302 Data Sheet\u003c\/a\u003e\n \n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407016-GMP-TL302-0100.pdf?v=1772517199\" type=\"application\/pdf\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 GMP-TL302 COA\u003c\/a\u003e\n \n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_GM-CSF_Protein-RUO.pdf?v=1772517199\" type=\"application\/pdf\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 TL-302 COA\u003c\/a\u003e\n \n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"display-search-keyword\" style=\"display:none\"\u003etl-302-0100, gmp-tl302-0010\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"RUO \/ 10μg","offer_id":51379040157877,"sku":"TL-302-0010","price":110.0,"currency_code":"USD","in_stock":true},{"title":"GMP \/ 100μg","offer_id":51379040190645,"sku":"GMP-TL302-0100","price":380.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-302-0010.jpg?v=1772428078"},{"product_id":"recombinant-human-ifn-γ-protein","title":"Recombinant Human IFN-γ Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Background --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eBackground\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eGranulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) is a pivotal glycosylated cytokine functioning extracellularly as a homodimer. Its core function is to stimulate the proliferation and differentiation of hematopoietic stem\/progenitor cells into granulocytes and monocytes (which mature into macrophages and dendritic cells).\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eLeveraging this, GM-CSF finds extensive application in cell and gene therapy. In cell therapy, it is a critical factor for the in vitro expansion of immune cells (e.g., dendritic cells for DC vaccines) and acts as an immune modulator in vivo to activate DCs and T cells, enhancing anti-tumor immunity.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eIn gene therapy, its encoding gene (located in the chromosome 5q31 region) serves as a potential target, or therapeutic GM-CSF can be delivered via vectors for localized and sustained expression.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: left;\"\u003eRecombinantly produced GM-CSF protein provides an essential tool for these applications, with its potential dual immunomodulatory effects requiring careful evaluation.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: #fff;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"3\"\u003eProduct Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 30%; font-weight: bold; background-color: #f8f9fa;\"\u003eParameter\u003c\/td\u003e\n \u003ctd style=\"width: 35%; font-weight: bold; text-align: center;\"\u003eRUO Grade\u003c\/td\u003e\n \u003ctd style=\"width: 35%; font-weight: bold; text-align: center;\"\u003eGMP Grade\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eCatalog Number\u003c\/td\u003e\n \u003ctd style=\"text-align: center;\"\u003eTL-105-0010\u003c\/td\u003e\n \u003ctd style=\"text-align: center;\"\u003eGMP-TL105-0200\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eInterferon-gamma, Interferon-γ, Immune interferon\u003c\/td\u003e\n \u003ctd\u003eInterferon-gamma, Interferon-γ, Immune interferon\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P01579\u003c\/td\u003e\n \u003ctd\u003eUniProt P01579\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003eGln24–Gln166\u003c\/td\u003e\n \u003ctd\u003eGln24–Gln166\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n \u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMolecular Weight\u003c\/td\u003e\n \u003ctd\u003e17.6 kDa\u003c\/td\u003e\n \u003ctd\u003e17.6 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;90% (SDS-PAGE)\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;90% (SDS-PAGE)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;0.1 EU\/µg\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;0.1 EU\/µg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eHT-29 cell proliferation inhibition assay,\u003cbr\u003e≥ 1.0 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003ctd\u003eHT-29 cell proliferation inhibition assay,\u003cbr\u003e≥ 1.0 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from PBS (pH 7.4), 6–8% mannitol\u003c\/td\u003e\n \u003ctd\u003eLyophilized from PBS (pH 7.4), 6–8% mannitol\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0; margin: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product is purified using advanced chromatographic techniques, achieving a purity level of over 95%, ensuring reliable and reproducible results in experiments.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Confirmed through multiple activity assays, this IFN-α protein effectively induces antiviral and antiproliferative effects in target cells, making it suitable for a range of research applications.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Produced with rigorous quality control measures to ensure consistent quality between batches, reducing variability and enhancing experimental reliability.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Manufactured without animal-derived components, adhering to animal-free standards and broadening its applicability for various research purposes.\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eVirology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the antiviral mechanisms of IFN-α, providing insights into its role in controlling viral infections and developing antiviral therapies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate the immunomodulatory effects of IFN-α on immune cell functions and interactions, contributing to a better understanding of immune responses and potential treatments for immune disorders.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eOncology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExplore the antiproliferative effects of IFN-α on cancer cells, offering valuable information for the development of cancer immunotherapies and treatment strategies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Culture\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUtilize IFN-α to enhance cell culture systems, providing a more controlled environment for studying cellular responses and drug effects.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px; margin: 10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Lyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored inthe original sealed container under desiccant. \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Reconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4)maintaining final concentration ≥100 µg\/mL to prevent adsorption. \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0;\"\u003e√ Handling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocument\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: #fff; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IFN-_Protein.pdf?v=1772516539\" target=\"_blank\"\u003e📄 GMP\/RUO TL105 Data Sheet\u003c\/a\u003e\n\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IFN-_Protein.pdf?v=1772516541\" target=\"_blank\"\u003e📄 GMP\/RUO TL105 SDS\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407015-TL-105-0010.pdf?v=1772516538\" target=\"_blank\"\u003e📄 TL-105-0010 COA\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2412010-GMP-TL105-0200.pdf?v=1772516544\" target=\"_blank\"\u003e📄 GMP-TL105-0200 COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"RUO \/ 10μg","offer_id":51379046154421,"sku":"TL-105-0010","price":99.0,"currency_code":"USD","in_stock":true},{"title":"GMP \/ 200μg","offer_id":51379046187189,"sku":"GMP-TL105-0200","price":400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-105-0010.jpg?v=1772429246"},{"product_id":"recombinant-human-il-2-protein","title":"Recombinant Human IL-2 Protein (High-Efficiency)","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n \n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eActivated T cells generally cannot survive for a long time in vitro culture, and the addition of IL-2 can promote their long-term and sustained proliferation.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe surface of stationary T cells does not express IL-2R and does not respond to IL-2. T cells activated by mitogen or other stimuli can express IL-2R and become target cells of IL-2. IL-2 can also induce increased IL-2R expression in target cells.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe expression of IL-2R on T cells is transient, generally reaching its peak 2–3 days after activation and disappearing around 6–10 days. With the disappearance of IL-2R, T cells lose their ability to respond to IL-2.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eTherefore, in order to maintain the long-term growth of normal T cells in vitro, it is necessary to constantly stimulate T cells with mitogen or other stimulators to maintain the expression of IL-2R.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eNK cells are the only lymphoid cells that normally express IL-2R and therefore always maintain reactivity to IL-2. However, only the IL-2R β chain and γ chains are expressed on stationary NK cells, which have a low affinity for IL-2 and can only react with high concentrations of IL-2.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: justify;\"\u003eOnce NK cells are activated, they express the IL-2R α chain, becoming a high-affinity receptor.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eCytokines Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eExpression Host\u003c\/td\u003e\n \u003ctd\u003eE. coli\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eTCGF, Lymphokine, Interleukin\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 90% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eDetermined by the dose-dependent stimulation of CTLL-2 cell proliferation, corresponding to an activity of ≥ 1 × 10⁷ U\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein, determined by the LAL method\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMolecular Mass\u003c\/td\u003e\n \u003ctd\u003eThe recombinant human IL-2 protein has a predicted molecular mass of 15.4 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile PBS, pH 7.4. Typically supplemented with 6% mannitol as a stabilizing protectant prior to lyophilization\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh-Potency IL-2:\u003c\/strong\u003e ≥1 × 10⁷ U\/mg bioactivity ensures strong and reproducible proliferation of activated T and NK cells.\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eTag-Free Design:\u003c\/strong\u003e Eliminates Fc-mediated off-target effects, supporting clean signaling in immune cell culture.\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eUltra-Low Endotoxin:\u003c\/strong\u003e \u0026lt;0.1 EU\/µg endotoxin, suitable for sensitive cell cultures and therapy process development.\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eOptimized Growth:\u003c\/strong\u003e Effectively sustains proliferation during the IL-2R expression window following activation.\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eStable Formulation:\u003c\/strong\u003e Mannitol-protected lyophilized format ensures excellent stability and reliable performance.\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCAR-T\/TCR-T Expansion\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports controlled and scalable expansion of genetically modified T cells during ex vivo manufacturing.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eNK Cell Activation\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePromotes NK cell proliferation and enhances cytotoxic activity and cytokine secretion.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eTIL \u0026amp; CIK Culture\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnables sustained growth of tumor-reactive and cytokine-induced killer cells in vitro.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eSignaling Studies\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUsed to study IL-2\/IL-2R signaling, receptor dynamics, and lymphocyte proliferation mechanisms.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n \u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n \u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human IL-2 Protein Data\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/gmp-tl906-2.jpg?v=1772089248\"\u003e\n \u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human IL-2 Protein Analysis\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized preparation can be stored at 2-8 ℃.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e6 months at -20℃ under sterile conditions after reconstitution.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e12 months at -80℃ under sterile conditions after reconstitution.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eRecommend to aliquot the protein into smaller quantities after reconstituting with water for injection, normal saline or PBS, and keep the diluted concentration above 100μg\/mL.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-2_Protein_high-efficiency.pdf?v=1772515346\" target=\"_blank\"\u003e📄 GMP-TL906 Data Sheet\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-2_Protein_Efficient_type.pdf?v=1772515346\" target=\"_blank\"\u003e📄 GMP-TL906 SDS\u003c\/a\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2502001-GMP-TL906-0100.pdf?v=1772515346\" target=\"_blank\"\u003e📄 GMP-TL906 COA\u003c\/a\u003e\n \n \u003c\/div\u003e\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"100μg","offer_id":43214487716021,"sku":"GMP-TL906-0100","price":95.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL906-0100.png?v=1772515280"},{"product_id":"recombinant-human-il-3-protein","title":"Recombinant Human IL-3 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive (same logic as reference)\n ========================== *\/\n\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px; \/* Desktop keeps normal layout *\/\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px; \/* Mobile horizontal scroll *\/\n }\n }\n\u003c\/style\u003e\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n\u003cp style=\"margin: 0; text-align: justify;\"\u003eRecombinant Human Interleukin-3 (IL-3) is a crucial cytokine involved in the regulation of hematopoiesis, stimulating the proliferation and differentiation of various blood cells. IL-3 exerts its effects by binding to the IL-3 receptor, initiating signaling pathways that are essential for the development and function of the immune system. This makes it a valuable tool for research in immunology, hematology, and cell biology.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\n\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eCytokines Details\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression Host\u003c\/td\u003e\n\u003ctd\u003eA DNA sequence encoding the human IL-3 (GenBank: AAA59146.1) was expressed with a His-tag at the C-terminus.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eSynonym\u003c\/td\u003e\n\u003ctd\u003eMCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eProtein Sequence\u003c\/td\u003e\n\u003ctd\u003eThe recombinant human IL-3 protein consists of 139 amino acids.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMolecular Mass\u003c\/td\u003e\n\u003ctd\u003ePredicts a molecular mass of 15.9 kD.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eQC Testing Purity\u003c\/td\u003e\n\u003ctd\u003e\u0026gt; 95% as determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003eHEK293 cells (Host verification)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized powder.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eStability\u003c\/td\u003e\n\u003ctd\u003eStore at -20°C or below to maintain product stability and activity. Avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eStorage\u003c\/td\u003e\n\u003ctd\u003eStable for long-term storage under recommended conditions, ensuring reliable performance.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%, ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expected biological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure high consistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eResearch the role of IL-3 in the regulation of blood cell production and mechanisms of hematopoiesis.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the effects of IL-3 on immune cell development and function in immune response.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUtilize IL-3 in studies focusing on stem cell differentiation and proliferation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate the impact of IL-3 on cell signaling pathways, survival, and proliferation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human IL-3 Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1_e48a1ebe-c991-4b61-917e-6beac15bb84e_600x600.jpg?v=1768809296\"\u003e\n\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human IL-3 Protein Analysis\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-3_Protein.pdf?v=1772515503\" target=\"_blank\"\u003e📄 GMP-TL511 Data Sheet\u003c\/a\u003e \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-3_Protein.pdf?v=1772515503\" target=\"_blank\"\u003e📄 GMP-TL511 SDS\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214488895669,"sku":"GMP-TL511-0050","price":260.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214488928437,"sku":"GMP-TL511-0100","price":460.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL511-0050.jpg?v=1772515493"},{"product_id":"recombinant-human-il-6-protein","title":"Recombinant Human IL-6 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe recombinant human IL-6- protein is produced in HEK-293 cells via transient transfection, featuring a C-terminal polyhistidine (His) tag for nickel-affinity purification.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eAs a pleiotropic α-helical cytokine, IL-6 activates JAK-STAT and MAPK signaling pathways by binding to the IL-6Rα\/gp130 heterodimeric receptor, regulating immune responses, hematopoiesis, and cellular differentiation.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eIn cell and gene therapy applications, it critically enables: ex vivo expansion of hematopoietic stem cells (HSCs) and T cells, enhancement of effector functions in NK and CAR-T cells, directed differentiation of induced pluripotent stem cells (iPSCs) toward hematopoietic lineages, and synergistic construction of vascularized tissue-engineered microenvironments.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: justify;\"\u003eThe native bioactive conformation is preserved, while the His-tag design ensures precise purification without Fc-mediated off-target effects, making it particularly suitable for regenerative medicine and cell therapy systems requiring spatiotemporal control of cytokine concentrations.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eCytokines Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eIL6, Interleukin-6, BSF2, HSF, IFNB2\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P05231\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003eVal30–Met212\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMolecular Weight\u003c\/td\u003e\n \u003ctd\u003e21.6 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 95% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eMeasured by TF-1 cell proliferation assay, corresponding to a specific activity of ≥ 5 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile PBS (pH 7.4), typically supplemented with 6% mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features (template: ✔ + bold title + original text, no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%, ensuring the reliability and reproducibility of experimental results.\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expected biological responses in target cells, suitable for a wide range of research applications.\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure high consistency between batches, reducing variability in experimental outcomes.\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements and broadening its application scope in research.\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications (template: 2-col cards; title before colon; body after colon; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the role of IL-6 in immune responses, inflammation, and autoimmune diseases, providing insights into potential therapeutic targets.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eOncology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate the effects of IL-6 on tumor cells, tumor microenvironment, and cancer therapy, aiding in the development of novel anti-cancer strategies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematopoiesis\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExplore the role of IL-6 in the regulation of blood cell production and its implications for treating hematological disorders.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eResearch the impact of IL-6 on cell signaling pathways, apoptosis, and cellular stress responses, contributing to a deeper understanding of cell biology.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Data Figures --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n \u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n \u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human IL-6 Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/gmp-tl512-2.jpg?v=1772413810\"\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant. \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eReconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration≥100µg\/mL to prevent adsorption. \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Instructions for Use --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-6_Protein.pdf?v=1772515660\" target=\"_blank\"\u003e📄 GMP-TL512 SDS\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2512003-GMP-TL512-0050.pdf?v=1772515660\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL512-0050 COA\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2510011-GMP-TL512-0100.pdf?v=1772515659\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL512-0100 COA\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-6_Protein.pdf?v=1772515660\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL512 Data Sheet\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214489190581,"sku":"GMP-TL512-0050","price":260.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214489223349,"sku":"GMP-TL512-0100","price":460.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL512-0050.jpg?v=1772414573"},{"product_id":"recombinant-human-il-7-protein","title":"Recombinant Human IL-7 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003c!-- Description --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe recombinant human IL-7-Fc fusion protein is a glycosylated functional dimer produced in CHO expression systems, engineered with a C-terminal human IgG1 Fc domain to enhance protein stability and receptor clustering efficacy.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eAs a pivotal member of the IL-2 cytokine family, IL-7 activates the JAK1\/JAK3-STAT5 signaling cascade via its heterodimeric receptor (IL-7Rα\/γc), driving survival, proliferation, and differentiation of T\/B\/NK cells while maintaining lymphocyte homeostasis through Bcl-2-mediated anti-apoptotic mechanisms and promoting CD4+\/CD8+ double-positive T-cell maturation during thymic development.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eIn cell therapy manufacturing, this fusion protein serves as a critical culture additive to enhance CAR-T cell metabolic fitness and memory phenotype formation through sustained PI3K-AKT-mTOR pathway activation. It synergizes with IL-15 to suppress exhaustion markers (e.g., PD-1\/TIM-3) while supporting hematopoietic stem cell differentiation into functional lymphoid progenitors, thereby improving the persistence and antitumor efficacy of adoptive immune cell products.\u003c\/p\u003e\n\u003cp style=\"margin: 0; text-align: justify;\"\u003eThe Fc-mediated dimeric configuration mimics native membrane-bound IL-7 bioactivity and optimizes pharmacokinetic profiles through extended serum half-life.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!-- Specifications --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\n\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n\u003cth colspan=\"2\" style=\"padding: 12px; text-align: left;\"\u003eCytokines Details\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd\u003eInterleukin-7, IL-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eUniProt P13232-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n\u003ctd\u003eAsp26–His177\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFusion Tag\u003c\/td\u003e\n\u003ctd\u003eHuman IgG1 Fc fragment fused to the C-terminus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n\u003ctd\u003e43.8 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e\u0026gt; 95% as determined by SDS-PAGE and HPLC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 0.01 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n\u003ctd\u003eExhibits dose-dependent proliferation of PHA-activated PBMCs with an ED\u003csub\u003e50\u003c\/sub\u003e of 0.5–20 ng\/mL and a specific activity \u0026gt; 1.0 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized from sterile 20 mM phosphate-buffered saline (PBS), pH 7.4, typically containing 6–8% (w\/v) mannitol as a stabilizing protectant\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c!-- Features (✔ + title from first line + body from second line; no content changes) --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003ePotently drives lymphocyte proliferation via IL-7Rα\/γc–STAT5 signaling, validated by PBMC assays.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eFc-Fusion Dimeric Design\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003eHuman IgG1 Fc fusion enhances protein stability, receptor clustering, and functional persistence.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eExcellent Batch Stability\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003eGMP-compliant manufacturing ensures consistent purity, activity, and ultra-low endotoxin levels.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eDMF Filed (038126)\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003eSupports regulatory readiness for cell and gene therapy development.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- Applications (2x2 cards; title = first line; body = second line; no content changes) --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eT Cell Expansion and Memory Formation\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnhances survival, metabolic fitness, and memory phenotype in CAR-T and T-cell cultures.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eNK Cell Activation and Maintenance\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePromotes NK cell proliferation and functional persistence in immunotherapy workflows.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell and Gene Therapy Manufacturing\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eIdeal as a cytokine supplement in GMP-aligned immune cell production processes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eAdvanced Immunology Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSuitable for studies requiring sustained IL-7 signaling and lymphocyte homeostasis control.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Data Figures --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Recombinant_Human_IL-7_Protein_600x600.jpg?v=1753148824\" alt=\"\" style=\"max-width: 100%; height: auto;\"\u003e\u003c\/div\u003e\n\u003c!-- Stability \u0026 Storage --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored inthe original sealed container under desiccant. \u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eReconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4)maintaining final concentration ≥100 µg\/mL to prevent adsorption. \u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- Cautions (Universal) --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!-- Documents --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-7_Protein.pdf?v=1772515901\" style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 GMP-TL506 SDS\u003c\/a\u003e \n \u003ca type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-7_Protein.pdf?v=1772515901\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 GMP-TL506 Data Sheet\u003c\/a\u003e\n \u003ca type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2410001-GMP-TL506-0050.pdf?v=1772515901\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 GMP-TL506-0050 COA\u003c\/a\u003e\n \u003ca type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2404010-GMP-TL506-0100.pdf?v=1772515901\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 GMP-TL506-0100 COA\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214491648181,"sku":"GMP-TL506-0050","price":260.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214491680949,"sku":"GMP-TL506-0100","price":460.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL506-0050.jpg?v=1772415364"},{"product_id":"recombinant-human-il-12-protein","title":"Recombinant Human IL-12 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe recombinant human IL-12 fusion protein is a heterodimer produced by transient transfection in HEK-293 cells, consisting of an IL-12A (p35) subunit with a 6×his-tag and an IL-12B (p40) subunit with an Fc-tag.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eAs a pivotal immunoregulatory cytokine, IL-12 drives naive T cell differentiation into Th1 cells and potently activates T cells and NK cells, stimulating IFN-γ and TNF-α production.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eCritically for cell and gene therapy, this protein is essential: it enables ex vivo expansion and activation of CAR-T cells and NK cells, enhancing their anti-tumor cytotoxicity; it is applied in immunotherapies against tumors, metastatic cancers, viral infections (e.g., AIDS), and as an adjuvant, functioning by eliciting potent Th1 immune responses and cytotoxicity; its anti-angiogenic activity also holds therapeutic potential.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: justify;\"\u003eThe native dimeric structure ensures full bioactivity, while the dual His\/Fc-tag design facilitates efficient purification and extends serum half-life, making it an ideal tool for immunotherapy applications.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eCytokines Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eIL-12, p70, Interleukin-12\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P29459-1 \u0026amp; P29460-1\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003eArg23–Ser219 (P29459-1) \u0026amp; Ile23–Ser328 (P29460-1)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eHis Tag \u0026amp; Fc Tag\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e~65 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 90% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eMeasured by PHA-activated PBMC proliferation assay, corresponding to a specific activity of ≥ 1.5 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile PBS (pH 7.4), typically supplemented with 6% mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features (✔ + bold title from colon-left + original text from colon-right; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Purified using advanced chromatographic techniques, this product achieves a purity level of over 95%, ensuring accurate and reproducible experimental results.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Validated through multiple activity assays, this IL-12 protein effectively promotes T cell differentiation and NK cell activity, making it suitable for a range of research applications.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Produced under stringent quality control measures to ensure high consistency between batches, reducing variability and enhancing experimental reliability.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Manufactured without the use of animal-derived components, adhering to animal-free standards and broadening its applicability for diverse research needs.\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications (2x2 cards; title = colon-left; body = colon-right; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the role of IL-12 in the regulation of immune responses, including the differentiation of T cells and the activation of NK cells, providing insights into immune mechanisms and potential therapeutic targets.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eOncology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExplore the effects of IL-12 on tumor immunity, including its ability to enhance the cytotoxic activity of immune cells against cancer cells, contributing to the development of immunotherapeutic approaches.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eInfectious Diseases\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate the role of IL-12 in host defense mechanisms against infections, offering valuable information for the development of new treatments for infectious diseases.\u003cbr\u003e\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eVaccine Development\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUtilize IL-12 in the design and testing of vaccines to enhance immune responses and improve vaccine efficacy.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Data Figures --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n \u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n \u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human IL-12 Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/gmp-tl508-2.jpg?v=1772415797\"\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eReconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥ 100 µg\/mL to prevent adsorption. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-12_Protein.pdf?v=1772519679\" target=\"_blank\"\u003e📄 GMP-TL508 Data Sheet\n\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-12_Protein.pdf?v=1772519679\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL508 SDS\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407011-GMP-TL508-0050.pdf?v=1772519679\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL508-0050 COA\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407012-GMP-TL508-0100.pdf?v=1772519679\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL508-0100 COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214492827829,"sku":"GMP-TL508-0050","price":260.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214492860597,"sku":"GMP-TL508-0100","price":460.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL508-0050.jpg?v=1772415690"},{"product_id":"recombinant-human-il-15-protein","title":"Recombinant Human IL-15 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe recombinant human IL-15 fusion protein is a genetically engineered chimeric immunomodulatory molecule constructed by tandem fusion of the IL-15 cytokine core, sushi domain of IL-15 receptor α (IL-15Rα), and human IgG Fc fragment through flexible linkers.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThis molecular design mimics the natural trans-presentation mechanism of IL-15, where the sushi domain mediates high-affinity binding to IL-15Rα to form stable superagonist complexes, while the Fc fragment enhances molecular stability, prolongs serum half-life, and achieves extended pharmacokinetic properties through FcRn-mediated recycling.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eIn the field of cell therapy, this fusion protein significantly enhances the expansion efficiency and viability of immune cells during in vitro culture processes, particularly in preparing highly active NK cell and tumor-specific T cell therapeutic products.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eBy persistently activating the IL-2\/IL-15 receptor βγ complex (CD122\/γc), it effectively promotes the proliferation and functional maintenance of CD8+ memory T cells, NK cells, and NKT cells, while preserving the metabolic fitness and anti-tumor phenotype of effector cells.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: justify;\"\u003eThis innovative structural design overcomes the limitations of natural IL-15 such as short half-life and low bioavailability, providing an optimized molecular tool for cancer immunotherapy and the development of cell therapy products.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eCytokines Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eInterleukin-15\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P40933 \u0026amp; Q13261\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003eP40933 (Asn23–Ser136 [Asn72Asp]) \u0026amp; Q13261 (Ile31–Arg95)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFusion Tag\u003c\/td\u003e\n \u003ctd\u003eHuman IgG1 Fc fragment fused to the C-terminus\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e53.5 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 95% as determined by SDS-PAGE and HPLC\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.01 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eMeasured by CTLL-2 cell proliferation assay with an ED\u003csub\u003e50\u003c\/sub\u003e of 0.2–3 ng\/mL, corresponding to a specific activity \u0026gt; 5.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile 20 mM phosphate-buffered saline (PBS), pH 7.4, typically containing 6–8% (w\/v) mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features (✔ + bold title before line break + original description after line break; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eIL-15 Superagonist Design\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eSushi domain–mediated trans-presentation enables sustained and potent IL-15 signaling.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eFc-Fusion Extended Stability\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eHuman IgG1 Fc enhances molecular stability and functional persistence via FcRn recycling.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eDemonstrates strong CTLL-2 proliferation activity with low ED₅₀ and reliable cytokine potency.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eDMF Filed (038127)\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eSupports regulatory readiness for GMP cell and gene therapy manufacturing.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications (2x2 cards; title before line break; body after line break; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eNK Cell Expansion and Activation\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eDrives robust NK cell proliferation while preserving cytotoxic and anti-tumor function.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCD8⁺ Memory T Cell Maintenance\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSustains long-term survival and functional fitness of tumor-specific T cells.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Therapy Manufacturing\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eOptimized cytokine supplement for NK- and T-cell–based CGT workflows.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCancer Immunotherapy Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnables development of next-generation immune effector cell products.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored inthe original sealed container under desiccant.  \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eReconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4)maintaining final concentration ≥100 µg\/mL to prevent adsorption. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-15_Protein.pdf?v=1772519280\" target=\"_blank\"\u003e📄 GMP-TL202 Data Sheet\n\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-15_Protein.pdf?v=1772519280\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP-TL202 SDS\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2406004-GMP-TL202-0050.pdf?v=1772519279\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP-TL202-0050 COA\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2406005-GMP-TL202-0100.pdf?v=1772519280\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP-TL202-0100 COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214493876405,"sku":"GMP-TL202-0050","price":260.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214493909173,"sku":"GMP-TL202-0100","price":460.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL202-0050.jpg?v=1772416670"},{"product_id":"recombinant-human-il-18-protein","title":"Recombinant Human IL-18 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eIL-18 is a pleiotropic proinflammatory cytokine belonging to the IL-1 superfamily, which requires caspase-1-mediated proteolytic activation to engage the heterodimeric IL-18Rα\/β receptor, triggering NF-κB and MAPK signaling pathways that drive IFN-γ production in Th1 cells, NK cells, and macrophages.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eIt synergizes with IL-12 to enhance IgG2a class switching while suppressing IL-4-dependent IgE\/IgG1 production.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eIn cell therapy manufacturing, the recombinant IL-18 protein serves as a critical culture component to augment CAR-T\/NK cell effector functions and persistence through coordinated action with IL-15\/IL-12, while potentiating FasL-mediated cytotoxicity and promoting memory T-cell differentiation, thereby optimizing the functional maturity and therapeutic potency of antitumor immune cell products.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: justify;\"\u003eIts activity is tightly regulated by IL-18 binding protein (IL-18BP), establishing a dynamic equilibrium that offers targeted therapeutic strategies for inflammatory and allergic disorders.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eCytokines Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eInterleukin-18, Iboctadekin, Interleukin-1 gamma, IFN-gamma-inducing factor\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt Q14116\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAmino Acid Sequence\u003c\/td\u003e\n \u003ctd\u003eTyr37–Asp193\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eTag-Free\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003e\u003cem\u003eE. coli\u003c\/em\u003e\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e18.2 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 95% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eInduces IFN-γ secretion in KG-1 cells with TNF-α co-stimulation, corresponding to a specific activity of ≥ 2.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile 20 mM phosphate-buffered saline (PBS), pH 7.4, typically containing 6–8% (w\/v) mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features (✔ + title before line break + original description after line break; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003ePotent IFN-γ Induction\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eStrongly activates NF-κB\/MAPK signaling to drive IFN-γ production in Th1 and NK cells.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eSynergistic Immuno-Activation\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eExhibits powerful synergy with IL-12 and IL-15 to amplify cytotoxic immune responses.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eValidated by KG-1 cell IFN-γ secretion assay, ensuring reliable functional potency.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eTag-Free Native Cytokine\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003ePreserves authentic IL-18 structure and signaling without fusion-induced bias.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications (2x2 cards; title before line break; body after line break; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCAR-T and NK Cell Functional Enhancement\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eBoosts effector function, cytotoxicity, and antitumor activity during cell manufacturing.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eIFN-γ–Driven Immune Activation Studies\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eIdeal for Th1 polarization and inflammatory signaling research.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCombination Cytokine Cell Culture Systems\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUsed with IL-12 \/ IL-15 to optimize immune cell maturation and persistence.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmuno-Oncology Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports development of highly potent immune effector cell therapies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Lyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored inthe original sealed container under desiccant. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Reconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4)maintaining final concentration ≥100 µg\/mL to prevent adsorption. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Handling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-18_Protein.pdf?v=1772519080\" target=\"_blank\"\u003e📄 GMP-TL902 Data Sheet\n\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-18_Protein.pdf?v=1772519080\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP-TL902 SDS\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-PrTE2505011GMP-TL902-0050.pdf?v=1772519081\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP-TL902COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214494564533,"sku":"GMP-TL902-0050","price":260.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL902-0050.png?v=1772417208"},{"product_id":"recombinant-human-il-21-protein","title":"Recombinant Human IL-21 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe recombinant human IL-21-Fc fusion protein is an innovative biologics engineered by covalently linking the human IL-21 pleiotropic cytokine with an immunoglobulin Fc domain through genetic recombination technology.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eAs a γc-chain cytokine family member secreted by antigen-activated CD4+ T cells (including Tfh and Th17 subsets) and NKT cells, IL-21 activates the JAK1\/JAK3-STAT1\/STAT3 signaling cascade via its heterodimeric receptor complex (IL-21R\/γc), orchestrating immune cell functions: potentiating CD8+ T\/NK cell-mediated tumor cytotoxicity, promoting Th17 polarization, suppressing Treg differentiation, and driving antibody affinity maturation through coordinated Tfh-B cell interactions.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThe Fc fusion design not only extends serum half-life but also enhances immunomodulatory efficacy via Fcγ receptor-mediated targeted delivery, demonstrating unique therapeutic potential in cancer immunotherapy and autoimmune disease intervention.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: justify;\"\u003eIn cell therapy manufacturing, the recombinant human IL-21-Fc fusion protein serves as a critical culture supplement to enhance the proliferation efficiency and effector cytotoxicity of engineered T\/NK cells via JAK-STAT pathway activation, while promoting memory T-cell phenotypes and suppressing activation-induced cell exhaustion (AICD), thereby supporting the generation of highly potent and durable antitumor immune cell products.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eCytokines Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eIL21, Za11, Interleukin-21\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt Q9HBE4-1\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAmino Acid Sequence\u003c\/td\u003e\n \u003ctd\u003eGln29–Ser126\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFusion Tag\u003c\/td\u003e\n \u003ctd\u003eHuman IgG1 Fc fragment fused to the C-terminus\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eCHO cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e41.9 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 95% as determined by SDS-PAGE and HPLC\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.01 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eInduces IFN-γ secretion in human NK-92 lymphoma cells with an ED\u003csub\u003e50\u003c\/sub\u003e ≤ 50 ng\/mL\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile 20 mM phosphate-buffered saline (PBS), pH 7.4, typically containing 6–8% (w\/v) mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features (✔ + title before line break + original description after line break; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eFc-Fusion Enhanced Durability\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eHuman IgG1 Fc fusion extends functional persistence and improves cytokine stability.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003ePotent JAK-STAT Activation\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eActivates IL-21R\/γc–JAK1\/JAK3–STAT1\/STAT3 signaling for strong immune modulation.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eDemonstrates robust IFN-γ induction in NK-92 cells with low ED₅₀ performance.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eDMF Filed (039117)\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eSupports regulatory readiness for GMP cell and gene therapy workflows.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications (2x2 cards; title before line break; body after line break; no wording changes) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eT Cell Expansion and Effector Enhancement\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePromotes proliferation, cytotoxic function, and memory phenotype in engineered T cells.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eNK Cell Cytotoxicity Optimization\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnhances NK cell antitumor activity while limiting activation-induced exhaustion.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Therapy Manufacturing\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eIdeal cytokine supplement for generating potent and durable T\/NK cell products.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCancer Immunotherapy Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports studies focused on immune activation, memory formation, and antitumor efficacy.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Lyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored inthe original sealed container under desiccant. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Reconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4)maintaining final concentration ≥100 µg\/mL to prevent adsorption. \u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Handling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_IL-21_Protein.pdf?v=1772518878\" target=\"_blank\"\u003e📄 GMP-TL509 Data Sheet\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_IL-21_Protein.pdf?v=1772518878\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL509 SDS\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2411005-GMP-TL509-0050.pdf?v=1772518877\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL509-0050 COA\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2411006-GMP-TL509-0100.pdf?v=1772518878\" type=\"application\/pdf\" target=\"_blank\"\u003e📄 GMP-TL509-0100 COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214523793589,"sku":"GMP-TL509-0050","price":260.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214523826357,"sku":"GMP-TL509-0100","price":460.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Recombinant_Human_IL-21_Protein.jpg?v=1772417634"},{"product_id":"recombinant-human-pdgf-bb-protein","title":"Recombinant Human PDGF-BB Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eThe recombinant human PDGF-BB-His fusion protein is a high-purity homodimeric growth factor produced in HEK-293 expression systems, featuring a C-terminal polyhistidine tag for nickel-affinity chromatography purification.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eAs a core member of the PDGF\/VEGF superfamily, PDGF-BB specifically engages PDGFR-β to activate Ras-MAPK and PI3K-Akt signaling pathways, driving directed migration, proliferation, and differentiation of mesenchymal stem cells, pericytes, and vascular smooth muscle cells while enhancing extracellular matrix adhesion through integrin αvβ3 upregulation.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eIn cell therapy applications, this protein serves as a critical component in 3D bioscaffold culture systems, where controlled release kinetics enhance ex vivo expansion and paracrine activation of mesenchymal stem cells (MSCs), synergize with VEGF to engineer functional vascular networks, and promote neural progenitor differentiation into oligodendrocyte precursor cells (OPCs), thereby creating vascularized microenvironments for tissue-engineered grafts.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: left;\"\u003eThe native disulfide-bonded dimeric configuration preserves full bioactivity, while the His-tag design enables precise purification without Fc-mediated off-target activation, making it particularly suitable for regenerative medicine applications requiring spatiotemporal control of growth factor concentrations.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: #fff;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"width: 35%; font-weight: bold; background-color: #f8f9fa;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd style=\"width: 65%;\"\u003ePlatelet-derived growth factor subunit B, PDGF-2, Platelet-derived growth factor beta polypeptide, Proto-oncogene c-Sis\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P01127\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003eSer82–Thr190\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e13.1 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 90% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile 20 mM phosphate-buffered saline (PBS), pH 7.4, typically containing 6–8% (w\/v) mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0; margin: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eNative Dimeric PDGF-BB Activity\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003ePreserves disulfide-bonded homodimer structure for authentic PDGFR-β signaling.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003ePotent MSC-Targeted Signaling\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eActivates Ras-MAPK and PI3K-Akt pathways to drive migration, proliferation, and differentiation of mesenchymal cells.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity, Low Endotoxin\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eHEK293 expression and His-tag purification ensure consistent quality for sensitive cell culture systems.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eExcellent Batch Stability\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eReliable performance across batches supports reproducible tissue engineering workflows.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eMesenchymal Stem Cell (MSC) Expansion\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnhances MSC proliferation and paracrine activity in 2D and 3D culture systems.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eVascularized Tissue Engineering\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSynergizes with VEGF to support pericyte recruitment and functional vascular network formation.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003e3D Bioscaffold-Based Cell Culture\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnables controlled growth factor delivery for spatially organized tissue constructs.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eNeural \u0026amp; Regenerative Medicine Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports neural progenitor differentiation and regeneration-oriented microenvironment design.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px; margin: 10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Lyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored inthe original sealed container under desiccant.\u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Reconstitution: Dissolve in sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4)maintaining final concentration ≥100 µg\/mL to prevent adsorption.\u003cbr\u003e\n\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0;\"\u003e√ Handling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocument\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: #fff; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_PDGF-BB_Protein.pdf?v=1772514486\" target=\"_blank\"\u003e📄 GMP-TL644 Data Sheet\u003c\/a\u003e\n\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_PDGF-BB_Protein.pdf?v=1772514487\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL644 SDS\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2408020-GMP-TL644-0050.pdf?v=1772514489\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL644-0050 COA\u003c\/a\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2408021-GMP-TL644-0100.pdf?v=1772514488\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL644-0100 COA\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":43214525792437,"sku":"GMP-TL644-0050","price":380.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":43214525825205,"sku":"GMP-TL644-0100","price":600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL644-0050.jpg?v=1772432373"},{"product_id":"recombinant-human-tnf-α-protein","title":"Recombinant Human TNF α Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:920px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\n \/* =========================\n Data Figures (image card)\n ========================== *\/\n .biofargo-figure-card{\n text-align:center;\n margin-top:20px;\n border:1px solid #eee;\n padding:15px;\n border-radius:8px;\n background:#fff;\n }\n .biofargo-figure-card img{\n max-width:100%;\n height:auto;\n }\n\u003c\/style\u003e\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\u003c!-- Description --\u003e\n\u003cdiv class=\"biofargo-section\" style=\"margin-top: 0;\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-card\"\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eThe recombinant human Tumor Necrosis Factor Alpha (TNF-α) protein is a high-purity homotrimeric cytokine produced in HEK-293 expression system via transient transfection, featuring a C-terminal polyhistidine tag for nickel-affinity chromatography purification.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eAs the prototypic member of the TNF superfamily, TNF-α is produced primarily by macrophages and exerts its broad spectrum of pleiotropic biological effects by binding to its receptors TNF-R1 (CD120a\/p55) and TNF-R2 (CD120b\/p75).\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eIt plays a central role in regulating immune cell activity, capable of inducing apoptotic cell death in certain tumor cell lines, triggering inflammation, inhibiting viral replication, and critically modulating processes such as cell proliferation, differentiation, lipid metabolism, and coagulation.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eHowever, dysregulation of TNF-α is implicated in a variety of human diseases, including cancer (exhibiting dual roles in both antitumorigenesis and tumor promotion\/metastasis), septic shock, fever, autoimmune diseases (such as rheumatoid arthritis and Crohn’s disease), graft-versus-host disease, Alzheimer’s disease, and major depression.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0;\"\u003eRecombinant TNF-α is utilized clinically as an immunostimulant under the INN tasonermin.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003eThe native homotrimeric configuration preserves full bioactivity, while the His-tag design enables precise purification.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Specifications --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrap\"\u003e\n\u003ctable class=\"biofargo-table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth style=\"width: 18%;\"\u003eProduct\u003c\/th\u003e\n\u003cth style=\"width: 22%;\"\u003eParameter\u003c\/th\u003e\n\u003cth style=\"width: 35%;\"\u003eSpecification\u003c\/th\u003e\n\u003cth class=\"center\" style=\"width: 25%;\"\u003eResults\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003c!-- TL-303-0010 --\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"10\" class=\"center\"\u003eTL-303-0010\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eAppearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentity\u003c\/td\u003e\n\u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVisible Particle\u003c\/td\u003e\n\u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMoisture\u003c\/td\u003e\n\u003ctd\u003e≤4.0%\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e1.0%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003epH\u003c\/td\u003e\n\u003ctd\u003e6.5~7.5\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e7.2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;95.0%\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMycoplasma\u003c\/td\u003e\n\u003ctd\u003eShould be negative\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSterility\u003c\/td\u003e\n\u003ctd\u003eNo growth\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiological Activity\u003c\/td\u003e\n\u003ctd\u003eIn the presence of metabolic inhibitor actinomycin D, cytotoxicity assay was performed on L929 cells, with specific activity ≥ 1.0 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e4.27 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c!-- GMP-TL303-0100 --\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"10\" class=\"center\"\u003eGMP-TL303-0100\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eAppearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentity\u003c\/td\u003e\n\u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVisible Particle\u003c\/td\u003e\n\u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMoisture\u003c\/td\u003e\n\u003ctd\u003e≤4.0%\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e0.6%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003epH\u003c\/td\u003e\n\u003ctd\u003e6.5~7.5\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e7.3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;95.0%\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMycoplasma\u003c\/td\u003e\n\u003ctd\u003eShould be negative\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSterility\u003c\/td\u003e\n\u003ctd\u003eNo growth\u003c\/td\u003e\n\u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiological Activity\u003c\/td\u003e\n\u003ctd\u003eIn the presence of metabolic inhibitor actinomycin D, cytotoxicity assay was performed on L929 cells, with specific activity ≥ 1.0 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003ctd class=\"center\"\u003e7.03 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Features (fixed 4; derived from provided content without adding data) --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n\u003cul class=\"biofargo-checklist\"\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eNative Homotrimeric TNF-α Activity\u003c\/strong\u003e\n\u003cp\u003eHomotrimeric configuration preserves full bioactivity for TNF-R1 (CD120a\/p55) and TNF-R2 (CD120b\/p75) engagement in downstream signaling studies.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHEK-293 Expression with His-Tag Purification\u003c\/strong\u003e\n\u003cp\u003eProduced via transient transfection in HEK-293 cells with a C-terminal polyhistidine tag for nickel-affinity chromatography purification.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eStringent QC for Cell-Based Assays\u003c\/strong\u003e\n\u003cp\u003eLots meet appearance\/identity\/visible particle criteria, with endotoxin \u0026lt;0.1 EU\/μg, mycoplasma negative, and sterility showing no growth.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eValidated L929 Cytotoxicity Bioassay\u003c\/strong\u003e\n\u003cp\u003eBioactivity measured by L929 cell cytotoxicity assay in the presence of actinomycin D, with lot results reported for TL-303-0010 and GMP-TL303-0100.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!-- Applications (2x2; aligned to Description logic) --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-grid\"\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eTNFR Signaling Studies\u003c\/h4\u003e\n\u003cp\u003eSupports mechanistic studies of TNF-R1\/TNF-R2-mediated immune signaling and downstream pathway activation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eL929 Cytotoxicity Assays\u003c\/h4\u003e\n\u003cp\u003eUsed in cytotoxicity assay workflows on L929 cells in the presence of actinomycin D for functional activity evaluation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eInflammation Research Models\u003c\/h4\u003e\n\u003cp\u003eApplicable for studying inflammatory mediator induction and immune-cell activity regulation in vitro.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"biofargo-app-card\"\u003e\n\u003ch4\u003eCancer and Immunology Studies\u003c\/h4\u003e\n\u003cp\u003eSupports research on TNF-α roles in tumor cell apoptosis and broader immunology-related investigations.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Data Figures --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-figure-card\"\u003e\u003cimg alt=\"Recombinant Human TNF-α Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1_3ca2b3c8-a9d1-4eb6-a032-f0d953092439.jpg?v=1772507389\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Stability \u0026 Storage (no fabricated durations; keep only what was provided) --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px; margin: 10px 0 0 0;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized powder: Store at -20°C or below to maintain product stability and activity.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eReconstitution: Not provided.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 0;\"\u003eHandling: Avoid repeated freeze-thaw cycles to prevent protein degradation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!-- Cautions (Universal) --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-caution\"\u003e\n\u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Documents (links not provided; keep CTA structure without fabricating URLs) --\u003e\n\u003cdiv class=\"biofargo-section\"\u003e\n\u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-docs\"\u003e\n\u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_TNF_Protein-GMP-TL303-0100.pdf?v=1772507565\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP-TL303 Data Sheet\u003c\/a\u003e \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_TNF_Protein-TL-303-0010.pdf?v=1772507565\" rel=\"noopener\" target=\"_blank\"\u003e📄 TL303 Data Sheet\u003c\/a\u003e \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_TNF_Protein.pdf?v=1772507564\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP\/RUO TL303 SDS\u003c\/a\u003e \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407014-TL-303-0010.pdf?v=1772507559\" rel=\"noopener\" target=\"_blank\"\u003e📄 TL-303 COA\u003c\/a\u003e \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407013-GMP-TL303-0100.pdf?v=1772507561\" rel=\"noopener\" target=\"_blank\"\u003e📄 GMP-TL303 COA\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"RUO \/ 10μg","offer_id":51379104907445,"sku":"TL-303-0010","price":104.0,"currency_code":"USD","in_stock":true},{"title":"GMP \/ 100μg","offer_id":51379104940213,"sku":"GMP-TL303-0100","price":320.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-303-0010.png?v=1772507188"},{"product_id":"recombinant-human-tpo-protein","title":"Recombinant Human TPO Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:920px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\n \/* =========================\n Data Figures (image card)\n ========================== *\/\n .biofargo-figure-card{\n text-align:center;\n margin-top:20px;\n border:1px solid #eee;\n padding:15px;\n border-radius:8px;\n background:#fff;\n }\n .biofargo-figure-card img{\n max-width:100%;\n height:auto;\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eRecombinant Human Thrombopoietin (TPO) is a functional protein transiently expressed in HEK-293 cells with a C-terminal 6×His tag.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eBy retaining the N-terminal 1–174 amino acid residues of TPO (the EPO-homologous domain essential for bioactivity) and removing the non-essential C-terminal glycosylated region, its molecular weight is optimized to 18–23 kDa.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eThis protein specifically binds to the c-Mpl receptor and activates the JAK\/STAT signaling pathway, playing a central role in hematopoietic stem cell culture and cell therapy applications.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIt drives directed differentiation of hematopoietic stem\/progenitor cells toward the megakaryocytic lineage, efficiently promoting in vitro expansion and maturation of megakaryocytes, as well as platelet production.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eThis provides critical support for establishing functional in vitro platelet production platforms, developing thrombocytopenia therapeutics, and advancing stem cell-based regenerative therapies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:25%;\"\u003eParameter\u003c\/th\u003e\n \u003cth style=\"width:37.5%;\"\u003eSpecification\u003c\/th\u003e\n \u003cth class=\"center\" style=\"width:37.5%;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eIdentity\u003c\/td\u003e\n \u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eVisible Particle\u003c\/td\u003e\n \u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMoisture\u003c\/td\u003e\n \u003ctd\u003e≤4.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e2.8%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003epH\u003c\/td\u003e\n \u003ctd\u003e6.5~7.5\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e7.3\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;90.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMycoplasma\u003c\/td\u003e\n \u003ctd\u003eShould be negative\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eCell proliferation assay performed with Mo7e cells demonstrated specific activity ≥ 5.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e3.13 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHEK293-Expressed Truncated TPO (Ser22–Leu195)\u003c\/strong\u003e\n \u003cp\u003eRecombinant human TPO expressed in HEK293 cells, corresponding to Ser22–Leu195 with Pro157Asn and Arg164Asn substitutions, retaining the EPO-homologous bioactive domain and optimized molecular weight (~19.5 kDa), with a C-terminal 6×His tag.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity and Controlled Quality Attributes\u003c\/strong\u003e\n \u003cp\u003ePurity \u0026gt;90% by SDS-PAGE, electrophoretic identity consistent with expected molecular weight, no visible particles, moisture 2.8%, pH 7.3 within 6.5–7.5 specification.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eLow Endotoxin and Sterility Assurance\u003c\/strong\u003e\n \u003cp\u003eEndotoxin \u0026lt;0.1 EU per µg (LAL method), mycoplasma negative, and sterility confirmed with no growth.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eValidated Mo7e Proliferation Activity\u003c\/strong\u003e\n \u003cp\u003eBiological activity measured by Mo7e cell proliferation assay, with specific activity ≥5.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg (measured 3.13 × 10\u003csup\u003e7\u003c\/sup\u003e IU\/mg).\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eHSPC Culture Support\u003c\/h4\u003e\n \u003cp\u003eBinds to c-Mpl receptor and activates JAK\/STAT signaling to support hematopoietic stem\/progenitor cell expansion.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eMegakaryocytic Differentiation\u003c\/h4\u003e\n \u003cp\u003eDrives directed differentiation of hematopoietic stem\/progenitor cells toward the megakaryocyte lineage in vitro.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eMegakaryocyte Maturation Studies\u003c\/h4\u003e\n \u003cp\u003ePromotes in vitro expansion and maturation of megakaryocytes for platelet generation studies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eIn Vitro Platelet Platforms\u003c\/h4\u003e\n \u003cp\u003eSupports development of functional in vitro platelet production systems and stem cell–based regenerative research.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Data Figures --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eData Figures\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-figure-card\"\u003e\n \u003cimg alt=\"Recombinant Human Thrombopoietin (TPO) Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/333_8ecaa9f9-d9d7-4609-98af-a40a3db9ddb2.png?v=1772506691\"\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left:20px; margin:10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Stable for 12 months at −80 °C or 6 months at −20 °C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eReconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eHandling: Aliquot to avoid repeated freeze–thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-caution\"\u003e\n \u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_TPO_Protein.pdf?v=1772506564\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-650 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_TPO_Protein.pdf?v=1772506563\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-650 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-PrTE2505001-TL-650-0050.pdf?v=1772506559\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-650 COA\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"RUO \/ 50μg","offer_id":43214502658229,"sku":"TL-650-0050","price":276.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-650-0050.png?v=1772506504"},{"product_id":"recombinant-human-vitronectin-protein","title":"Recombinant Human Vitronectin Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:920px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\n \/* =========================\n Data Figures (image card)\n ========================== *\/\n .biofargo-figure-card{\n text-align:center;\n margin-top:20px;\n border:1px solid #eee;\n padding:15px;\n border-radius:8px;\n background:#fff;\n }\n .biofargo-figure-card img{\n max-width:100%;\n height:auto;\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eThe recombinant human Vitronectin (VTN) protein is a high-purity multifunctional glycoprotein transiently expressed in HEK-293 cells, featuring a C-terminal polyhistidine tag for precise purification via nickel-affinity chromatography.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eAs a core component of the extracellular matrix (ECM), vitronectin mediates cell adhesion, spreading, and migration through RGD sequence-specific binding to integrin receptors (αvβ3, αvβ5, αvβ1, etc.), while regulating stem cell proliferation and differentiation.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIn cell and gene therapy applications, this protein serves as a critical element in serum-free culture systems: its multimeric form efficiently incorporates into biomimetic scaffolds, providing in vivo-like adhesion signals for mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) to significantly enhance ex vivo expansion efficiency and stemness maintenance.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eFurthermore, it synergizes with growth factors (e.g., TGF-β) to optimize microenvironments for organoid development and tissue-engineered grafts, promoting vascularized tissue regeneration.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eThe native conformation ensures its full bioactivity.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:25%;\"\u003eParameter\u003c\/th\u003e\n \u003cth style=\"width:37.5%;\"\u003eSpecification\u003c\/th\u003e\n \u003cth class=\"center\" style=\"width:37.5%;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eIdentity\u003c\/td\u003e\n \u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eVisible Particle\u003c\/td\u003e\n \u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMoisture\u003c\/td\u003e\n \u003ctd\u003e≤4.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e2.29%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003epH\u003c\/td\u003e\n \u003ctd\u003e6.5~7.5\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e7.01\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;95.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMycoplasma\u003c\/td\u003e\n \u003ctd\u003eShould be negative\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eBy measuring its ability to promote hiPS cell adhesion, this effect ED50 \u0026lt; 2.4 μg\/mL\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e1.139 μg\/mL\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHEK293-Expressed His-Tagged Vitronectin\u003c\/strong\u003e\n \u003cp\u003eRecombinant human vitronectin (Asp19–Leu478) expressed in HEK293 cells with a C-terminal 6×His-tag, predicted molecular weight 53 kDa.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity and Quality Compliance\u003c\/strong\u003e\n \u003cp\u003ePurity \u0026gt;95.0% with electrophoretic identity consistent with the expected molecular weight; no visible particles; moisture 2.29%; pH 7.01 within 6.5–7.5 specification.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eLow Endotoxin and Sterility Assurance\u003c\/strong\u003e\n \u003cp\u003eEndotoxin level \u0026lt;0.1 EU\/µg (LAL method), mycoplasma negative, and sterility confirmed with no growth.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eValidated hiPS Cell Adhesion Activity\u003c\/strong\u003e\n \u003cp\u003eBiological activity determined by promotion of hiPS cell adhesion with ED₅₀ ≤2.4 µg\/mL (measured 1.139 µg\/mL).\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003ehiPS Cell Adhesion Support\u003c\/h4\u003e\n \u003cp\u003ePromotes adhesion of human induced pluripotent stem (hiPS) cells for in vitro culture applications.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eSerum-Free Stem Cell Culture\u003c\/h4\u003e\n \u003cp\u003eFunctions as a defined extracellular matrix component supporting MSC and iPSC expansion and stemness maintenance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eCell Culture Surface Coating\u003c\/h4\u003e\n \u003cp\u003eUsed for coating culture plates to enhance cell attachment via integrin-mediated interactions.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eOrganoid and Tissue Engineering\u003c\/h4\u003e\n \u003cp\u003eSupports microenvironment optimization in organoid development and tissue-engineered graft studies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Data Figures --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eData Figures\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-figure-card\"\u003e\n \u003cimg alt=\"Recombinant Human Vitronectin (VTN) Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/gmp-tl651-2_600x600.jpg?v=1748505222\"\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left:20px; margin:10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Stable for 24 months at -20°C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eReconstitution: For lyophilized powder, dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-caution\"\u003e\n \u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_Vitronectin_Protein.pdf?v=1772506061\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL651 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_Vitronectin_Protein.pdf?v=1772506061\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL651 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-PrTE2505010-GMP-TL651-0100.pdf?v=1772506063\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL651 COA\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"100μg","offer_id":43214503248053,"sku":"GMP-TL651-0100","price":235.0,"currency_code":"USD","in_stock":true},{"title":"1000μg","offer_id":45422806204597,"sku":"GMP-TL651L-1000","price":270.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL651-0100.png?v=1772505947"},{"product_id":"recombinant-human-lif-protein","title":"Recombinant Human LIF Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eThe recombinant human leukemia inhibitory factor (LIF) protein is transiently expressed in HEK-293 cells and features a C-terminal His-tag for purification.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eAs a pleiotropic IL-6 family cytokine, LIF signals through the LIFR-α\/gp130 receptor complex, activating the JAK\/STAT pathway.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0; text-align: left;\"\u003eIts core applications in cell and gene therapy include maintaining pluripotency and suppressing spontaneous differentiation of mouse embryonic stem cells (mESCs) for in vitro expansion culture, and promoting the differentiation of neural progenitor cells into cholinergic neurons.\u003c\/p\u003e\n \u003cp style=\"margin: 0; text-align: left;\"\u003eDesigned to preserve native bioactivity, this protein is suited for regenerative medicine applications such as stem cell therapy and neural repair.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: #fff;\"\u003e\n \u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 35%; font-weight: bold; background-color: #f8f9fa;\"\u003eSynonyms\u003c\/td\u003e\n \u003ctd style=\"width: 65%;\"\u003eCDF, DIA, HILDA, Leukemia Inhibitory Factor, MLPLI\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n \u003ctd\u003eUniProt P15018\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n \u003ctd\u003eSer23–Phe202\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n \u003ctd\u003eC-terminal 6×His-tag\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd\u003e20.5 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 95% as determined by SDS-PAGE and HPLC\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.01 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n \u003ctd\u003eLyophilized from sterile PBS (pH 7.4), typically supplemented with 6% mannitol as a stabilizing protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style-type: none; padding: 0; margin: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e Purified using advanced chromatographic techniques, this product achieves a purity level of over 95%, ensuring accurate and reproducible experimental results.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Validated through multiple activity assays, this LIF protein effectively promotes cell differentiation and survival, making it suitable for a range of research applications.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Produced under stringent quality control measures to ensure high consistency between batches, reducing variability and enhancing experimental reliability.\u003cbr\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Manufactured without the use of animal-derived components, adhering to animal-free standards and broadening its applicability for diverse research needs.\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStudy the role of LIF in maintaining the pluripotency of embryonic stem cells and promoting their differentiation into various cell lineages, advancing research in regenerative medicine.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvestigate the effects of LIF on immune cell function and differentiation, providing insights into immune responses and potential therapeutic applications.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eOncology\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExplore the role of LIF in cancer cell biology, including its impact on tumor growth and metastasis, contributing to the development of novel cancer therapies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n \u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematopoiesis\u003c\/h4\u003e\n \u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eUtilize LIF to study its role in the regulation of hematopoietic stem cells and progenitor cells, offering valuable information for the treatment of hematological disorders.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px; margin: 10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Lyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003e√ Reconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥ 100 µg\/mL to prevent adsorption. \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0;\"\u003e√ Handling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocument\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n \u003ca style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: #fff; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_LIF_Protein.pdf?v=1772516338\" target=\"_blank\"\u003e📄 GMP-TL633 Data Sheet\u003c\/a\u003e\n\n \u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_LIF_Protein.pdf?v=1772516337\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL633 SDS\u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"100μg","offer_id":43217786732725,"sku":"GMP-TL633-0100","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL633-0100_9910037c-e02d-4489-a0eb-c5155b611335.png?v=1772516346"},{"product_id":"native-shc-protein-from-shrimp-a-substitute-for-klh","title":"Native Shrimp hemocyanin protein( From shrimp, a substitute for KLH)-EpiZyme","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eShrimp hemocyanin (SHC), a highly soluble hemocyanin from the Penaeus vannamei (P. vannamei) , is used as a substitute for KLH. Similar to KLH, SHC serves as a carrier protein for conjugation of hapten (including peptides, nucleic acids, drugs, or toxins). The conjugates would make these haptens highly immunogenic. The immunogenicity of SHC is comparable to KLH. However, the solubility is significantly higher, especially after hapten conjugation. Thus, SHC is advantageous for antibody or vaccine generation (reference).\u003c\/p\u003e\n\u003ch2\u003eSpecification\u003c\/h2\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cstrong\u003eHemocyanin (Non-activated)\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%; height: 68px;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003e\u003cstrong\u003eCatalog #\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003eHW101S\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003e10 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003eHW101\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003e100 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003eHW101L\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; height: 17px;\"\u003e100 mg×10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp style=\"text-align: center;\"\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003cstrong\u003eHemocyanin (SMCC activated)\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable border=\"1\" style=\"border-collapse: collapse; width: 99.9001%; height: 68px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003e\u003cstrong\u003eCatalog #\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003eHW102S\u003c\/td\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003e2 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003eHW102\u003c\/td\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003e10 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003eHW102L\u003c\/td\u003e\n\u003ctd style=\"width: 50.0464%; text-align: center; height: 17px;\"\u003e100 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eFeatures\u003c\/span\u003e\u003c\/h2\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eHighly immunogenic ：\u003c\/strong\u003e\u003cspan\u003eSHC owns the comparable \u003c\/span\u003e\u003cspan\u003eimmunogenicity to KLH\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eHigh-yield conjugation：\u003c\/strong\u003e\u003cspan\u003eConjugation efficiency higher than KLH\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eExcellent solubility：\u003c\/strong\u003e\u003cspan\u003eSHC is more soluble than KLH , and is \u003c\/span\u003e\u003cspan\u003ecompatible with poorly soluble haptens\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eHighly purity：\u003c\/strong\u003e\u003cspan\u003ePurity ≥ 98%\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eExcellent performance：\u003c\/strong\u003e\u003cspan\u003eVerified through hundreds of antibody \u003c\/span\u003e\u003cspan\u003egeneration test\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eHigh cost-performance ratio：\u003c\/strong\u003e\u003cspan\u003eThe price is lower than KLH\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cspan\u003eSHC could be used for rabbit polyclonal antibody generation\u003c\/span\u003e\u003c\/h2\u003e\n\u003cdiv\u003e\n\u003cspan\u003ePeptides targeting the indicated proteins were designed and conjugated to SHC. Rabbit serum was harvested 30 days after \u003c\/span\u003e\u003cspan\u003ethe first immunization.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-17-44.png?v=1714378727\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cspan\u003e\u003cspan style=\"color: rgb(196, 42, 12);\"\u003e\u003cstrong\u003eA\u003c\/strong\u003e\u003c\/span\u003e Confirmation of the rabbit serum application in WB detection. Of note, equal cell numbers were loaded.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-22-08.png?v=1714378944\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003cspan\u003e\u003cspan style=\"color: rgb(196, 42, 12);\"\u003e\u003cstrong\u003eB\u003c\/strong\u003e\u003c\/span\u003e Confirmation of the rabbit serum application in IHC detection. Various organs were used for test.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan\u003eSHC could be used for mouse monoclonal antibody development\u003c\/span\u003e\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-28-29.png?v=1714379413\"\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-29-09.png?v=1714379413\"\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-29-31.png?v=1714379413\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch2\u003e\u003cspan\u003eSHC owns the comparable immunogenicity to KLH\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-33-32.png?v=1714379652\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-33-53.png?v=1714379652\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eGeneration of SHC-peptide conjugates\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-36-48.png?v=1714379872\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-37-27.png?v=1714379872\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eSHC purification\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-04-29_16-39-54.png?v=1714380014\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"EpiZyme","offers":[{"title":"Non-activated \/ 10mg","offer_id":44082965741749,"sku":"HW101S","price":40.6,"currency_code":"USD","in_stock":true},{"title":"Non-activated \/ 100mg","offer_id":44082965774517,"sku":"HW101","price":337.4,"currency_code":"USD","in_stock":true},{"title":"Non-activated \/ 100mg×10","offer_id":44082965807285,"sku":"HW101L","price":2564.8,"currency_code":"USD","in_stock":true},{"title":"SMCC activated \/ 2mg","offer_id":44082965840053,"sku":"HW102S","price":60.2,"currency_code":"USD","in_stock":true},{"title":"SMCC activated \/ 10mg","offer_id":44082965872821,"sku":"HW102","price":198.8,"currency_code":"USD","in_stock":true},{"title":"SMCC activated \/ 100mg","offer_id":44082965905589,"sku":"HW102L","price":1398.6,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1_6e67cbf4-b9d0-48bb-b782-c29359edba6b.png?v=1732877823"},{"product_id":"rat-vascular-endothelial-growth-factor-165-vegf-165-animal-free","title":"Rat Vascular Endothelial Growth Factor-165 (VEGF-165) - Animal Free","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eVascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.\u003cbr\u003eShips ambient. Store frozen at -20 to -10°C\u003c\/p\u003e","brand":"Gemini","offers":[{"title":"10 ug","offer_id":44115924975797,"sku":"300-946P-10","price":465.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":44115925008565,"sku":"300-946P-100","price":3970.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":44115925041333,"sku":"300-946P-500","price":19197.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":44115924943029,"sku":"300-946P-1","price":37268.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/BlurredLabel-gf_3b348799-c6e2-4d0b-b158-7795237fc595.jpg?v=1732881123"},{"product_id":"recombinant-human-tgfb1-protein","title":"Recombinant Human TGFB1 Protein","description":"\u003cp\u003e\u003cspan\u003eDescription\u003cbr\u003e\u003cbr\u003eRecombinant Human TGFB1 Protein (Transforming Growth Factor Beta 1) is a bioactive cytokine known for its crucial role in regulating cell proliferation, differentiation, and immune responses. TGFB1 is initially synthesized as a proprotein that undergoes proteolytic cleavage to yield the mature, active TGF-beta-1 and the latency-associated peptide (LAP). This recombinant form includes the functional core sequence of the mature protein and is ideal for use in in vitro studies requiring biologically active TGF-beta-1.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003eProtein general information\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable border=\"1\" style=\"height: 155px; width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eProtein name\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003etransforming growth factor beta 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 53px;\"\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eAlternative protein names\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eTransforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide, LAP, Transforming growth factor beta-1, TGF-beta-1]\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eGene name\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eTGFB1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eAlternative gene name\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eTGFB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eAccession\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eP01137\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eOrganism\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003e\n\u003cem\u003eHomo sapiens\u003c\/em\u003e (Human)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eFull length\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003e390 amino acids\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eProduct Information\u003c\/span\u003e\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eProduct name\u003c\/td\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eRecombinant Human TGFB1 Protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003ePredicted molecular mass\u003c\/td\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003e55 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eExpression host\u003c\/td\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eHEK293\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003ePurification tag\u003c\/td\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eMBP at N-terminus,6xHis at C-terminus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eForm\u003c\/td\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003e0.15 M Phosphate buffered saline, pH 7.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003eShipping, storage and shelf life\u003c\/td\u003e\n\u003ctd style=\"width: 49.9663%; height: 3px; text-align: center; vertical-align: middle;\"\u003e\n\u003cp\u003eShipped on dry ice. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\u003cp\u003eUpon receipt,\u003c\/p\u003e\n\u003cp\u003e* 2 days when stored at 2 to 8 °C after thawing\u003c\/p\u003e\n\u003cp\u003e* Up to 12 months when aliquoted and stored at -20 to -80 °C\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eCore sequence\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"col-4 pl10 ptb5\"\u003eCore sequence start: Asp281\u003cbr\u003eCore sequence stop: Ser390\u003c\/p\u003e\n\u003cp class=\"col-8 plr10 ptb5 wb f12\"\u003e......DTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS......\u003c\/p\u003e\n\u003cdiv class=\"col-8 plr10 ptb5 f12\" style=\"text-align: left;\"\u003e\n\u003cp\u003eNote:The core sequence of the recombinant protein is shown above. The N and C termini have shortened by 0-10 amino acids. The exact sequence is proprietary information powered by SIEVE®.\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eProduct data\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSDS-PAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/31ebc4370166f179d3bfdc3e4fceb5b0_600x600.jpg?v=1717572446\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv\u003e\u003cspan\u003eThe purified product was run on 15% SDS-PAGE at reducing conditions. The gel was stained with Coomassie brilliant blue and destained.\u003c\/span\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!----\u003e","brand":"Absea","offers":[{"title":"Frozen \/ 100ug","offer_id":44248006852789,"sku":"P00073QCSN-F100","price":124.0,"currency_code":"USD","in_stock":true},{"title":"Frozen \/ 1mg","offer_id":44248006820021,"sku":"P00073QCSN-F1","price":618.0,"currency_code":"USD","in_stock":true},{"title":"Freeze-dried \/ 100ug","offer_id":44248006918325,"sku":"P00073QCSN-FD100","price":161.0,"currency_code":"USD","in_stock":true},{"title":"Freeze-dried \/ 1mg","offer_id":44248006885557,"sku":"P00073QCSN-FD1","price":804.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/31ebc4370166f179d3bfdc3e4fceb5b0.jpg?v=1732881327"},{"product_id":"apc-h-2db-lcmv-gp33-c9m-kavynfatm-mhc-tetramer","title":"APC-H-2Db\/LCMV gp33 (C9M) (KAVYNFATM) MHC Tetramer","description":"\u003ch2\u003eDescription \u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eThis product is a tetramer of biotinylated peptide\/MHC complex with streptavidin mainly composed of LCMV-derived peptide of KAVYNFATM sequence covering 33-41 and H-2Db molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"proshow-list-specifications-tit\"\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"border-collapse: collapse; width: 100%; height: 162px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eAllele\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eH-2Db\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eClass\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eClass I\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eMHC Species\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eAntigen\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eLCMV gp33 (C9M)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eAntigen Species\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eLCMV\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003ePeptide\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eKAVYNFATM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eRange\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003e33-41\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eConjugate\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eAPC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eApplication\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 18px; text-align: center;\"\u003eFCM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"proshow-list-specifications-tit\"\u003eTarget\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%; height: 198px;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 126px;\"\u003e\n\u003ctd style=\"width: 38.2188%; height: 126px; text-align: center;\"\u003eAntigen Introduction\u003c\/td\u003e\n\u003ctd style=\"width: 61.7812%; height: 126px; text-align: center;\"\u003eLymphocytic choriomeningitis (LCM) is a rodent-borne viral infectious disease that presents as aseptic meningitis, encephalitis or meningoencephalitis. Its causative agent is the lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae. The name was coined by Charles Armstrong in 1934.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 36px;\"\u003e\n\u003ctd style=\"width: 38.2188%; height: 36px; text-align: center;\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd style=\"width: 61.7812%; height: 36px; text-align: center;\"\u003eLCMV GP1; Lymphocytic choriomeningitis virus Glycoprotein 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 38.2188%; height: 18px; text-align: center;\"\u003eGene ID\u003c\/td\u003e\n\u003ctd style=\"width: 61.7812%; height: 18px; text-align: center;\"\u003e1491875\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 38.2188%; height: 18px; text-align: center;\"\u003eUniProt ID\u003c\/td\u003e\n\u003ctd style=\"width: 61.7812%; height: 18px; text-align: center;\"\u003eP26804\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c!----\u003e","brand":"Creative Biolabs","offers":[{"title":"50 tests","offer_id":44393347842229,"sku":"HM512","price":1545.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Snipaste_2024-07-03_13-48-08.png?v=1732866026"},{"product_id":"bd-1-beta-defensin-1-47a-a-human-biofargo","title":"BD-1, beta-Defensin 1 (47a.a), human","description":"\u003ch2\u003eMore Info\u003c\/h2\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003eBD-1, beta-Defensin 1 (47a.a), human: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues.\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cstrong\u003eUnitProt ID: P60022\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\n\u003cbr\u003e\u003cstrong\u003eNumber of Containers\u003c\/strong\u003e:1\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\n\u003cbr\u003e\u003cstrong\u003eRefrigeration Requirements\u003c\/strong\u003e:Freezer\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\n\u003cstrong\u003eShipping Conditions\u003c\/strong\u003e:ICE\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\n\u003cbr\u003e\u003cstrong\u003eUNSPSC Code\u003c\/strong\u003e:12352202\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\n\u003cstrong\u003eUNSPSC Category\u003c\/strong\u003e:Other Enzymes\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"pro-info\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ch2 class=\"pro-info\"\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/info.RC220-12-Recombinant_Human_beta-Defensin_1_rHu_BD-1.pdf?v=1734055348\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eProduct Info\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003eDisclaimer: For laboratory research use only.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"BioBasic","offers":[{"title":"5μg","offer_id":44907139236021,"sku":"RC220-5μg","price":80.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RC332-23B.SIZE.10ug_1_470.jpg?v=1734512183"},{"product_id":"streptavidin-biofargo","title":"Streptavidin","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eStreptavidin: Streptavidin is a tetrameric protein composed of four identical subunits. Each subunit binds one biotin molecule with a KD of ~1 x 10-15 M. The preparation contains an N- and C-terminal shortened variant (core streptavidin) with improved properties concerning homogeneity, solubility, resistance towards proteolytic degradation and accessibility of the biotin binding pocket as compared to native streptavidin.The Avidin-Biotin binding interaction is one of the strongest in nature dissociation constant = 10 -15 M). This interaction is often exploited as a means for enhancing detection in immunohistochemistry and nucleic acid hybridizations.Bio Basic's Streptavidin has a highest specific activity (\u0026gt;17 units\/mg protein). This electrophoretically-pure protein is guaranteed free of DNase, RNase and protease activity and is provided as a lyophilized powder. It may be easily conjugated to affinity columns, enzymes, antibodies or nucleic acid probes using any standard protocol\u003c\/p\u003e\n\u003ch2\u003eSpecification\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"border-collapse: collapse; width: 90%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center;\"\u003eCAS\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e9013-20-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eGrade\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eBiotech\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eAppearance\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eWhite Freeze-dried Powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eWhite Freeze-dried Powder\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e650 ± 150 mg\/g powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e≥17Units\/mg \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eSDS-PAGE Electophoresis Purity\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e≥95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eHPLC Purity\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e≥95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003epH\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e6.5 ± 0.5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e53.0 ± 5.3 KDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003eBacterial Endotoxins\u003c\/td\u003e\n\u003ctd style=\"width: 48.8427%; text-align: center;\"\u003e≤1.0EU\/ug rSTA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eStorage\u003c\/h2\u003e\n\u003cp\u003eStore frozen. Keep dry. Warm to room temperature before opening.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/info.SE497_T4C1_2020.pdf?v=1734155829\" target=\"_blank\"\u003e\u003cstrong\u003eINFO\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA.SE497-NO_LOT.pdf?v=1734155828\" target=\"_blank\"\u003e\u003cstrong\u003eCOA\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca type=\"application\/pdf\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS.SE497-Streptavidin.pdf?v=1734155829\" target=\"_blank\"\u003e\u003cstrong\u003eSDS\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003eDisclaimer: For laboratory research use only.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"BioBasic","offers":[{"title":"1mg","offer_id":44909495451829,"sku":"SE497-1mg","price":74.0,"currency_code":"USD","in_stock":true},{"title":"5mg","offer_id":44909495484597,"sku":"SE497-5mg","price":294.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/web-1g-vial-v1_103.jpg?v=1745200103"},{"product_id":"protein-a-biofargo","title":"Protein A","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eProtein A: Protein A is a 40-60 KD surface Protein originally found in the cell wall of the bacteria Staphylococcus aureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two-component system called ArlS-ArlR. It has found use in biochemical research because of its ability to bind immunoglobulins. It binds proteins from many of mammalian species, most notably IgG’s. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. The result of this type of interaction is that, in serum, the bacteria will bind IgG molecules in the wrong orientation (in relation to normal antibody function) on their surface which disrupts opsonization and phagocytosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNumber of Containers\u003c\/strong\u003e:1\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRefrigeration Requirements\u003c\/strong\u003e:Freezer\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eShipping Conditions\u003c\/strong\u003e:ICE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNSPSC Code\u003c\/strong\u003e:12352202\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNSPSC Category\u003c\/strong\u003e:Other Proteins\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDG\u003c\/strong\u003e:No\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e:(-15 to -20)℃\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSterile\u003c\/strong\u003e:No\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/info.PB0789_V2.0.pdf?v=1734164441\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eINFO\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003eDisclaimer: For laboratory research use only.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"BioBasic","offers":[{"title":"10mg","offer_id":44909976682677,"sku":"PB0789-10mg","price":38.0,"currency_code":"USD","in_stock":true},{"title":"50mg","offer_id":44909976715445,"sku":"PB0789-50mg","price":151.0,"currency_code":"USD","in_stock":true},{"title":"250mg","offer_id":44909976748213,"sku":"PB0789-250mg","price":605.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/web-250g-bottle-v1_403_1.jpg?v=1734511992"},{"product_id":"actin","title":"Actin","description":"\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eGrade\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eBiotech\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eRabbi t Muscle\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eAppearance\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eA lyophilized powder.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eSDS gel\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eSatisfactory\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eA280 @ mg\/ml\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eReport assay value\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eDescription\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003ePrepared by modification of the procedure of Spudich and Watt, J. Biol. Chem., 246, 4866 (1971) \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e4℃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA.ALS001041-NO_LOT.pdf?v=1746857027\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eCOA\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/MSDS.ALS001041-Actin.pdf?v=1746857027\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eMSDS\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"BioBasic","offers":[{"title":"1mg","offer_id":45362399805621,"sku":"ALS001041-1mg","price":104.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/2_1e164a45-175c-4038-b52c-87303512c08c.jpg?v=1746859104"},{"product_id":"human-il1a","title":"Human IL1a","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin 1 (IL-1) , is a name that designates two proteins, IL-1 alpha and IL-1 beta, which are the products of distinct genes, but which show approximately 25% amino acid sequence identity and which recognize the same cell surface receptors. Although IL-1 production is generally considered to be a consequence of inflammation, recent evidence suggests that IL-1 is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen. Cells in particular known to produce IL-1 include osteoblasts, monocytes, macrophages, keratinocytes, Kupffer cells, hepatocytes, thymic and salivary gland epithelium, Schwann cells, fibroblasts and glia (oligodendroglia, astrocytes and microglia). IL-1 alpha and IL-1 beta are both synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately17,000 Da. Neither precursor contains a typical hydrophobic signal peptide sequence and most of the precursor form of IL-1 alpha remains in the cytosol of cells, although there is evidence for a membrane-bound form of the precursor form of IL-1 alpha. The IL-1 alpha precursor reportedly shows full biological activity in the EL-4 assay. Among various species, the amino acid sequence of mature IL-1 alpha is conserved 60% to 70% and human IL-1 has been found to be biologically active on murine cell lines. Both forms of IL-1 bind to the same receptors, designated type I and type II. Evidence suggests that only the type I receptor is capable of signal transduction and that the type II receptor may function as a decoy, binding IL-1 and thus preventing binding of IL-1 to the type I receptor.\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e1. Nicklin MJ,et al. (1994) Genomics. 19(2):382-4. \u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e2. March CJ, et al. (1985) Nature. 315(6021):641-7. \u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e3. Bankers-Fulbright JL, et al. (1996) Life Sci. 59(2):61-83. \u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e4. Dinarello CA, et al. (1997) Semin Oncol. 24 (3 Suppl 9):S9-81-S9-93.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003cbr\u003e\n\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHematopoietin-1; IL1 alpha; IL-1 alpha; IL1; IL1A; IL-1A; IL1-ALPHA; IL1F1; IL-1F1;BAF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eQ53QF9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL-1 alpha\/IL-1F1 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSer113-Ala271\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e18.0 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured in a cell proliferation assay using D10.G4.1 mouse helper Tcells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 0.6-6 pg\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL1a_sds_480x480.jpg?v=1754449657\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL1a_Gel_filtration_480x480.jpg?v=1754449857\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL1a_Bioactivity_480x480.jpg?v=1754449989\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2 style=\"text-align: start;\"\u003eDocuments\u003c\/h2\u003e\n\u003cp style=\"text-align: start;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP210.pdf?v=1754450176\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL1a\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":45403434942645,"sku":"RP210-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":45403434975413,"sku":"RP210-50UG","price":464.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":45403435008181,"sku":"RP210-1MG","price":3708.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a.jpg?v=1747900099"},{"product_id":"recombinant-human-bfgf-protein-heat-stable","title":"Recombinant Human bFGF Protein (Heat Stable)","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive \n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 600px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 600px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 8px;\n padding: 6px;\n background: #fff;\n }\n\n .biofargo-spec-table {\n min-width: 720px;\n }\n }\n\u003c\/style\u003e\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003c!-- Description --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eAs a core member of the FGF family, bFGF selectively binds to FGFR1c\/2c\/3c\/4 receptor subtypes via its β-trefoil structure, activating the Ras-MAPK and PI3K-AKT signaling axes to regulate critical physiological processes, including cell proliferation, migration, differentiation, and angiogenesis.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eIn cell therapy applications, bFGF serves as an essential component of serum-free stem cell culture systems, sustaining the undifferentiated state of human pluripotent stem cells (hPSCs) through sustained ERK1\/2 pathway activation while stabilizing Nanog\/Oct4 expression. It further synergizes with BMP inhibitors to prevent spontaneous germ layer differentiation.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 10px 0; text-align: justify;\"\u003eThis recombinant thermostable human basic fibroblast growth factor (bFGF-HS) is engineered via an AI-driven protein design platform and produced in E. coli as a tag-free protein. While preserving the native heparin-binding domain (residues 128–144) and biological activity, the optimized sequence significantly enhances thermal stability and in vitro potency.\u003c\/p\u003e\n\u003cp style=\"margin: 0; text-align: justify;\"\u003eCompared to wild-type bFGF, this mutant exhibits an extended half-life in culture systems, reducing medium replenishment frequency and contamination risks, making it particularly suitable for large-scale stem cell culture, tissue engineering, and regenerative medicine research.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!-- Specifications --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\n\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\n\u003cth colspan=\"2\" style=\"padding: 12px; text-align: left;\"\u003eCytokines Details\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa; width: 30%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd\u003eFGF2, FGFB, FGF basic, HBGF-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eUniProt P09038-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpressed Region\u003c\/td\u003e\n\u003ctd\u003eGly59–Ser210 with an N-terminal methionine and several site mutations\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eTag\u003c\/td\u003e\n\u003ctd\u003eTag-free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eE. coli\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePredicted Molecular Weight\u003c\/td\u003e\n\u003ctd\u003e17.0 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e\u0026gt; 90% as determined by SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 0.1 EU per 1 μg of protein (LAL method)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n\u003ctd\u003eMeasured by HUVEC cell proliferation assay, corresponding to a specific activity of ≥ 1.0 × 10\u003csup\u003e6\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized from sterile PBS (pH 7.4), typically supplemented with 6% mannitol as a stabilizing protectant\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c!-- Features (✔ + title before line break + original description after line break; no wording changes) --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHeat-Stable Engineered Variant\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003eAI-designed mutations significantly enhance thermal stability while preserving native bFGF activity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eSustained ERK\/AKT Signaling\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003eProvides prolonged FGFR activation to support continuous cell proliferation and survival.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003eValidated by HUVEC proliferation assay, ensuring reliable potency in serum-free culture systems.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eExcellent Batch Stability\u003c\/strong\u003e\n\u003cp style=\"margin: 6px 0 0 0;\"\u003eConsistent performance across batches reduces variability in long-term cell culture workflows.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- Applications (2x2 cards; title before line break; body after line break; no wording changes) --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHuman iPSC Maintenance\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eMaintains pluripotency by stabilizing Nanog\/Oct4 expression and preventing spontaneous differentiation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eMesenchymal Stem Cell (MSC) Expansion\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePromotes robust MSC proliferation and migration in serum-free conditions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eLarge-Scale Stem Cell Culture\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eExtended half-life reduces media change frequency and contamination risk.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eRegenerative Medicine \u0026amp; Tissue Engineering Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports angiogenesis, cell migration, and growth factor–dependent tissue models.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- Stability \u0026 Storage --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e√ Lyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e√ Reconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥ 100 µg\/mL to prevent adsorption. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e√ Handling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- Cautions (Universal) --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact technical support if assistance is required.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!-- Documents --\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_bFGF_Heat_Stable_Protein.pdf?v=1772518668\" style=\"display: inline-block; padding: 10px 20px; background-color: #0056b3; color: white; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 TL-787 Data Sheet\u003c\/a\u003e \n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_bFGF_Heat_Stable_Protein.pdf?v=1772518668\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 TL-787 SDS\u003c\/a\u003e\n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_bFGF_Heat_Stable_Protein.pdf?v=1772518668\" style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" target=\"_blank\"\u003e📄 TL-787 SDS\u003c\/a\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"highlighter--hover-tools\" style=\"display: none;\"\u003e\n\u003cdiv id=\"highlighter--hover-tools--container\"\u003e\n\u003cdiv class=\"highlighter--icon highlighter--icon-copy\" title=\"Copy\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"highlighter--icon highlighter--icon-change-color\" title=\"Change Color\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"highlighter--icon highlighter--icon-delete\" title=\"Delete\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":45422707867829,"sku":"TL-787-0050","price":380.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL787-0050.png?v=1772418237"},{"product_id":"recombinant-human-scf-protein-1","title":"Recombinant Human SCF Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:920px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\n \/* =========================\n Data Figures (image card)\n ========================== *\/\n .biofargo-figure-card{\n text-align:center;\n margin-top:20px;\n border:1px solid #eee;\n padding:15px;\n border-radius:8px;\n background:#fff;\n }\n .biofargo-figure-card img{\n max-width:100%;\n height:auto;\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eRecombinant Human Stem Cell Factor (SCF) is a multifunctional cytokine produced by fibroblasts and endothelial cells that binds the c-Kit receptor, existing in soluble (~18.5 kDa dimer) and transmembrane forms via alternative splicing.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eDuring development, it regulates hematopoiesis (fetal liver\/bone marrow), germ cell and neural development, and melanocyte localization. In adulthood, it maintains hematopoietic stem cell (HSC) homeostasis by governing survival, proliferation, differentiation, and mobilization within the bone marrow niche, while also stimulating mast cell growth.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIn vitro, SCF potently synergizes with cytokines like G-CSF, GM-CSF, and IL-3 to stimulate hematopoietic progenitor proliferation and differentiation. In vivo, combined with G-CSF, it clinically enhances peripheral blood CD34+ cell yields by 2–3 fold versus G-CSF alone.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eThis product is GMP manufactured in mammalian cells with strict control of residuals (host protein, nucleic acid) and pathogens, ensuring full traceability.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:25%;\"\u003eParameter\u003c\/th\u003e\n \u003cth class=\"center\" style=\"width:75%;\"\u003eSpecification\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eSynonyms\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eC-kit ligand; Mast cell growth factor (MGF); Stem cell factor\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eAccession\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eUniProt P21583-1\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eExpressed Region\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eGlu26-Ala189\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eTag\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eC-terminal 6×His-tag\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eExpression System\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePredicted Molecular Weight\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e19.3 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurity\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e\u0026gt; 90% as determined by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eEndotoxin\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e\u0026lt; 0.1 EU per 1 µg of protein (LAL method)\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eActivity\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eMeasured in a cell proliferation assay using Mo7e cells, corresponding to a specific activity of ≥ 2.0 × 10\u003csup\u003e5\u003c\/sup\u003e IU\/mg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eForm\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eLyophilized from sterile PBS (pH 7.4), typically supplemented with 6% mannitol as a protectant\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features (fixed 4; remove unprovided RUO\/GMP purity\/moisture\/pH claims) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHEK293-Expressed SCF (Glu26–Ala189)\u003c\/strong\u003e\n \u003cp\u003eRecombinant human SCF corresponding to Glu26–Ala189, expressed in HEK293 cells with a C-terminal 6×His-tag; predicted molecular weight 19.3 kDa.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity with Defined Identity\u003c\/strong\u003e\n \u003cp\u003ePurity \u0026gt; 90% as determined by SDS-PAGE, supporting reliable performance in cell-based workflows.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eLow Endotoxin for Sensitive Cell Culture\u003c\/strong\u003e\n \u003cp\u003eEndotoxin \u0026lt; 0.1 EU per 1 µg of protein (LAL method), helping reduce background responses in hematopoietic cultures.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eValidated Mo7e Proliferation Bioactivity\u003c\/strong\u003e\n \u003cp\u003eActivity measured in a Mo7e cell proliferation assay, corresponding to a specific activity of ≥ 2.0 × 10\u003csup\u003e5\u003c\/sup\u003e IU\/mg.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications (2x2) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eHSC Homeostasis Support\u003c\/h4\u003e\n \u003cp\u003eBinds the c-Kit receptor to support HSC survival, proliferation, differentiation, and mobilization in vitro.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eProgenitor Cell Expansion\u003c\/h4\u003e\n \u003cp\u003eUsed to stimulate hematopoietic progenitor proliferation and differentiation, including synergistic use with other cytokines.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eMast Cell Growth Studies\u003c\/h4\u003e\n \u003cp\u003eSupports mast cell growth and related immunology research workflows.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eCD34\u003csup\u003e+\u003c\/sup\u003e Mobilization Research\u003c\/h4\u003e\n \u003cp\u003eApplied in studies evaluating increased peripheral blood CD34\u003csup\u003e+\u003c\/sup\u003e yields in combination settings such as G-CSF.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Data Figures --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eData Figures\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-figure-card\"\u003e\n \u003cimg alt=\"Recombinant Human Stem Cell Factor (SCF) Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/gmp-tl504_6ebc31e2-7cd3-4ebd-839c-612534d95f00_600x600.png?v=1748503228\"\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage (fixed 3-line structure; keep separate TL-504 and GMP-TL504 without adding data) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n\n \u003cdiv class=\"biofargo-card\" style=\"margin-bottom:12px;\"\u003e\n \u003cp style=\"margin:0 0 8px 0; font-weight:800;\"\u003eTL-504\u003c\/p\u003e\n \u003cul style=\"padding-left:20px; margin:0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eReconstitution: Dissolve contents in 200 µL sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration about 50 µg\/mL.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 8px 0; font-weight:800;\"\u003eGMP-TL504\u003c\/p\u003e\n \u003cul style=\"padding-left:20px; margin:0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Stable for 12 months at -80°C or 6 months at -20°C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eReconstitution: Dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥ 100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-caution\"\u003e\n \u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-RUO-Recombinant_Human_SCF_Protein.pdf?v=1772508484\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-504 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_SCF_Protein.pdf?v=1772508484\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP\/RUO TL504 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407008-TL-504-0010.pdf?v=1772508484\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-504 COA\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407009-GMP-TL504-0050.pdf?v=1772508484\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL504-0050 COA\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2407008-TL-504-0010.pdf?v=1772508484\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL504-0100 COA\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-GMP-Recombinant_Human_SCF_Protein.pdf?v=1772508484\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL504 Data Sheet\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"RUO \/ 10μg","offer_id":45422796210357,"sku":"TL-504-0010","price":126.0,"currency_code":"USD","in_stock":true},{"title":"GMP \/ 50μg","offer_id":51379070664885,"sku":"GMP-TL504-0050","price":380.0,"currency_code":"USD","in_stock":true},{"title":"GMP \/ 100μg","offer_id":51379070697653,"sku":"GMP-TL504-0100","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-504-0010_baa71433-ceb3-472e-8dd8-9f137b89ccaa.jpg?v=1772508675"},{"product_id":"human-plgf-pgf-pigf","title":"Human PLGF\/PGF\/PIGF","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eHuman PLGF involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI.\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241366782133,"sku":"RP964-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241366814901,"sku":"RP964-50UG","price":598.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241366847669,"sku":"RP964-1MG","price":5768.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_bf52b084-3681-48fe-adc2-ca7eb67bbfc5.jpg?v=1750428166"},{"product_id":"mouse-lif","title":"Mouse LIF","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eRecombinant mouse LIF (leukemia inhibitory factor) is commonly used in cell culture to maintain the pluripotency of stem cells. LIF is a widely expressed pleiotropic member of the IL-6 family of cytokines (1-3). Mature mouse LIF is expressed as a highly and variably glycosylated 32-62 kDa monomer that shares 78%, 91%, 80%, 76%, and 78% aa sequence identity with human, rat, canine, bovine, and porcine LIF, respectively (4). LIF functions through a heterodimeric receptor complex containing a ligand-binding subunit, LIF R alpha \/CD118, and a signal transducing subunit, gp130 (2, 4, 5). gp130 also serves as a subunit of the receptor complexes for Oncostatin M, Cardiotrophin-1, CNTF, IL-6, IL-11, and IL-27 (2, 5). A soluble form of mouse LIF R alpha can be generated by alternative splicing (6). Depending on the cells and their context, LIF either opposes or favors differentiation (2, 7). LIF produced by the uterine endometrium supports successful implantation of the embryo, promotes proliferation and maintenance of pluripotency in embryonic stem cells, and favors proliferation of progenitor cell types such as hematopoietic stem cells (2, 5, 7). LIF can also function as an autocrine growth factor in some pancreatic cancers, but it induces differentiation in the myeloid leukemic cell line M1 (1, 8). Tumor cell-derived LIF can also induce formation of immunosuppressive tumor-associated macrophages (9). LIF promotes endometrial remodeling and differentiation of adipocytes and cardiac smooth muscle cells (2, 3, 10). It promotes regulatory T cell and inhibits Th17 cell differentiation, thus down-regulating inflammation and contributing to immune tolerance during pregnancy and in the nervous system (2, 3, 5, 7).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp\u003e1. Moreau, J.F. et al. (1988) Nature 336:690.\u003c\/p\u003e\n\u003cp\u003e2. Trouillas, M. et al. (2009) Eur. Cytokine Netw. 20:51.\u003c\/p\u003e\n\u003cp\u003e3. Metcalfe, S.M. (2011) Genes Immun. 12:157.\u003c\/p\u003e\n\u003cp\u003e4. Gearing, D.P. et al. (1987) EMBO J. 6:3995.\u003c\/p\u003e\n\u003cp\u003e5. Cheng, J.G. et al. (2001) Proc. Natl. Acad. Sci. USA 98:8680.\u003c\/p\u003e\n\u003cp\u003e6. Tomida, M. et al. (1993) FEBS lett. 334:193.\u003c\/p\u003e\n\u003cp\u003e7. Paiva, P. et al. (2009) Cytokine Growth Factor Rev. 20:319.\u003c\/p\u003e\n\u003cp\u003e8. Kamohara, H. et al. (2007) Int. J. Oncol. 30:977.\u003c\/p\u003e\n\u003cp\u003e9. Duluc, D. et al. (2007) Blood 110:4319.\u003c\/p\u003e\n\u003cp\u003e10. Zouein, F.A. et al. (2013) Eur. Cytokine Netw. 24:11\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eleukemia inhibitory factor; LIF;CDF; D Factor; DIA; differentiation inhibitory activity\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP09056\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived mouse LIF protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePro25-Phe203\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e20 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse; height: 90px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003e\u0026gt; 95%, determined by SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 36px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eMeasured by its ability to induce IL-6 secretion by M1 mouse myeloid leukemia cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eThe EC50 for this effect is 0.05-0.2 ng\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE \u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Mouse_LIF_SDS-PAGE.jpg?v=1755766184\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eGel filtration\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Mouse_LIF_Gel_filtration.jpg?v=1755766184\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Mouse_LIF_Bioactivity.jpg?v=1755766184\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP740.pdf?v=1755766232\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eMouse LIF\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241367077045,"sku":"RP740-10UG","price":165.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241367109813,"sku":"RP740-50UG","price":351.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241367142581,"sku":"RP740-1MG","price":2884.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_5f834b55-2a3c-4b94-b33d-8ab920de7aa2.jpg?v=1750428176"},{"product_id":"human-sftpd-n-flag","title":"Human Sftpd (N-flag）","description":"The human Sftpd is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The protein may also be involved in surfactant metabolism.","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241367339189,"sku":"RP962-10UG","price":165.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241367371957,"sku":"RP962-50UG","price":351.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241367404725,"sku":"RP962-1MG","price":2884.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_57d611d5-c319-492e-a584-4dd69c27dd03.jpg?v=1750428188"},{"product_id":"mouse-il21","title":"Mouse IL21","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin-21(IL-21) is an approximately 14 kDa four-helix-bundle cytokine in the family of cytokines that utilize the common gamma chain as a receptor subunit. gamma c is also a subunit of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15 (1). IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells (2-6). It exerts its biological effects through a heterodimeric receptor complex of gamma c and the IL-21-specific IL-21 R (2, 7). Tfh-derived IL-21 plays an important role in the development of humoral immunity through its autocrine effects on the Tfh cell and paracrine effects on immunoglobulin affinity maturation, plasma cell differentiation, and B cell memory responses (4, 8, 9). It is also required for the migration of dendritic cells to draining lymph nodes (10). IL-21 regulates several aspects of T cell function. It co-stimulates the activation, proliferation, and survival of CD8+ T cells and NKT cells and promotes Th17 cell polarization (3, 5, 6, 11, 12). It blocks the generation of regulatory T cells and their suppressive effects on CD4+ T cells (13, 14). IL-21 R engagement enhances the cytolytic activity and IFN-gamma production of activated NK cells but limits the expansion of resting NK cells (15). IL-21 suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation (16). Dysregulation of the IL-21\/IL-21 R system contributes to the development of multiple immunological disorders (1, 17).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp\u003e1.Leonard, W.J. et al. (2008) J. Leukoc. Biol. 84:348.\u003c\/p\u003e\n\u003cp\u003e2. Parrish-Novak, et al. (2000) Nature 408:57.\u003c\/p\u003e\n\u003cp\u003e3. Coquet, J.M. et al. (2007) J. Immunol. 178:2827.\u003c\/p\u003e\n\u003cp\u003e4. Vogelzang, A. et al. (2008) Immunity 29:127.\u003c\/p\u003e\n\u003cp\u003e5. Korn, T. et al. (2007) Nature 448:484.\u003c\/p\u003e\n\u003cp\u003e6. Nurieva, R. et al. (2007) Nature 448:480.\u003c\/p\u003e\n\u003cp\u003e7. Asao, H. et al. (2001) J. Immunol. 167:1.\u003c\/p\u003e\n\u003cp\u003e8. Zotos, D. et al. (2010) J. Exp. Med. 207:365.\u003c\/p\u003e\n\u003cp\u003e9. Rankin, A.L. et al. (2011) J. Immunol. 186:667.\u003c\/p\u003e\n\u003cp\u003e10. Jin, H. et al. (2009) J. Clin. Invest. 119:47.\u003c\/p\u003e\n\u003cp\u003e11. Frohlich, A. et al. (2009) Science 324:1576.\u003c\/p\u003e\n\u003cp\u003e12. Yi, J.S., et al. (2009) Science 324:1572.\u003c\/p\u003e\n\u003cp\u003e13. Peluso, I. et al. (2007) J. Immunol. 178:732.\u003c\/p\u003e\n\u003cp\u003e14. Bucher, C. et al. (2009) Blood 114:5375.\u003c\/p\u003e\n\u003cp\u003e15. Kasaian, M.T. et al. (2002) Immunity 16:559.\u003c\/p\u003e\n\u003cp\u003e16. Tamagawa-Mineoka, R. et al. (2011) J. Invest. Dermatol. 131:1513.\u003c\/p\u003e\n\u003cp\u003e17. Ma, J. et al. (2011) Cytokine 56:133.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eCVID11; IL21; IL-21; IL-21Za11interleukin-21; interleukin 21; interleukin-21 isoform; Za11\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eQ9ES17\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived mouse IL-21 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePro25-Ser146\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e15.0 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse; height: 90px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003e\u0026gt; 95%, determined by SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 36px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eMeasured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eThe EC50 for this effect is 0.2-2.3 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE \u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Mouse_IL21_SDS-PAGE.jpg?v=1755748989\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Mouse_IL21_Bioactivity.jpg?v=1755748989\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP640.pdf?v=1755749019\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eMouse IL21\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241367568565,"sku":"RP640-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241367601333,"sku":"RP640-50UG","price":598.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241367634101,"sku":"RP640-1MG","price":5768.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_859ab769-2b82-41e6-a075-c8c53ef6abeb.jpg?v=1750428197"},{"product_id":"mouse-il23","title":"Mouse IL23","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12 (1-5). The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Mouse p19 cDNA encodes a 196 amino acid residue (aa) precursor protein with a putative 19 aa signal peptide and 177 aa mature protein. Human and mouse p19 share 70% aa sequence identity. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R). IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human Tnbsp;cells, the effects of IL-23 is restricted to memory T cells. In mouse, IL-23 but not IL-12, has also been shown to induce memory T cells to secret IL-17, a potent proinflammatory cytokine. IL-12 and IL-23 can induce IL-12 production from mouse splenic DC of both the CD8- and CD8+ subtypes, however only IL-23 can act directly on CD8+ DC to mediate immunogenic presentation of poorly immunogenic tumor\/self peptide.\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp\u003e1. Oppmann, B. et al. (2000) Immunity 13:715.\u003c\/p\u003e\n\u003cp\u003e2. Lankford, C.S. and D.M. Frucht (2003) J. Leukoc. Biol. 73:49.\u003c\/p\u003e\n\u003cp\u003e3. Parham, C. et al. (2002) J. Immunol. 168:5699.\u003c\/p\u003e\n\u003cp\u003e4. Belladonna, M.L. et al. (2002) J. Immunol. 168:5448.\u003c\/p\u003e\n\u003cp\u003e5. Aggarwal, S. et al. (2003) J. Biol. Chem. 278:1910.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIL-23 p19\/IL-12 p40; IL23; IL-23; IL-23A; IL-23-A; IL-23p19; IL-23p19\/IL-12p40; IL23P19P19\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP43432 (p40) \u0026amp; Q9EQ14 (p19)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived mouse IL-23 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ep40 (Met1-Ser335) \u0026amp; p19 (Val22-Ala196)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e57.9 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse; height: 90px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003e\u0026gt; 95%, determined by SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 36px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eMeasured by its ability to induce IL-17 secretion by mouse splenocytes.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eThe EC50 for this effect is 0.005-0.25 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Mouse_IL23_SDS-PAGE.jpg?v=1755677878\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Mouse_IL23_Bioactivity.jpg?v=1755677879\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP619.pdf?v=1755677575\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eMouse IL23\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241367863477,"sku":"RP619-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241367896245,"sku":"RP619-50UG","price":598.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241367929013,"sku":"RP619-1MG","price":5768.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_65d2a2da-7d37-42c5-826e-b492b9207ba5.jpg?v=1750428207"},{"product_id":"human-ir","title":"Human IR","description":"The Insulin Receptor (gene name INSR, designated CD220) is a type I transmembrane glycoprotein in the Insulin\/IGF Receptor family of receptor tyrosine kinases that share structural similarity and overlapping intracellular signaling events. The 1382 amino acid (aa) human Insulin R preproprotein (B isoform) is processed by proteolysis to remove the signal peptide and produce an extracellular alpha portion (aa 28-762), and an extracellular\/transmembrane\/cytoplasmic beta subunit (aa 763-1382). The extracellular domain (ECD) contains two homologous globular domains separated by a cysteine-rich domain and followed by three fibronectin type III domains. The intracellular region contains insulin-receptor substrate (IRS) docking sites, the kinase domain, and a phosphotyrosine-containing linker region.) IR-A expression is highest in fetal tissues and cancer cells, while IR-B is concentrated in adult differentiated cells (1-5).","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241368191157,"sku":"RP770-10UG","price":165.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241368223925,"sku":"RP770-50UG","price":351.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241368256693,"sku":"RP770-1MG","price":2884.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_90d760dc-3b6c-4e1a-b34d-96645c51040e.jpg?v=1750428216"},{"product_id":"human-beta-2-microglobulin","title":"Human Beta-2-microglobulin","description":"A serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241368453301,"sku":"RP605-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241368486069,"sku":"RP605-50UG","price":598.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241368518837,"sku":"RP605-1MG","price":5768.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_0feb119c-fdb8-4160-b547-ff3dc12a7ee8.jpg?v=1750428228"},{"product_id":"human-il5","title":"Human IL5","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin 5 (IL5) , is a secreted glycoprotein that belongs to the alpha -helical group of cytokines (1 - 3). IL5 is present as a covalently linked antiparallel dimer (4, 5). Mature human IL-5 shares 70%, 70%, 62%, 71%, 70% and 66%, aa sequence identity with mouse, rat, canine, equine, feline and porcine IL5, respectively and shows cross-reactivity with mouse IL5. IL5 is primarily produced by CD4+ Th2 cells, but also by activated eosinophils, mast cells, EBV-transformed B cells, Reed-Sternberg cells in Hodgkin’s disease, and IL2-stimulated invariant natural killer T cells (7, 8). IL5 increases production and mobilization of eosinophils and CD34+ progenitors from the bone marrow and causes maturation of eosinophil precursors outside the bone marrow (1, 6, 9, 10). The receptor for human IL5, mainly expressed by eosinophils, but also found on basophils and mast cells, consists of a unique ligand-binding subunit (IL5R alpha) and a shared signal-transducing subunit, beta c (3, 6, 11). IL5R alpha first binds IL5 at low affinity, then associates with preformed beta c dimers, forming a high-affinity receptor (12). IL5 also binds proteoglycans, potentially enhancing its activity (13). Soluble forms of IL5R alpha antagonize IL5 and can be found in vivo (10, 14).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e1. Rosenberg, H. F. et al. (2007) J. Allergy Clin. Immunol. 119:1303.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e2. Elsas, P.X. and M. I. G. Elsas (2007) Curr. Med. Chem. 14:1925.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e3. Martinez-M, M. and D. P. Huston (2003) J. Allergy Clin. Immunol. 112:653.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e4. Minamitake, Y. et al. (1990) J. Biochem. 107:292.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e5. McKenzie, A. N. et al. (1991) Mol. Immunol. 28:155.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e6. Shakoory, B. et al. (2004) J. Interferon Cytokine Res. 24:271.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e7. Lalani, T. et al. (1999) Ann. Allergy Asthma Immunol. 82:317.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e8. Sakuishi, K. et al. (2007) J. Immunol. 179:3452.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e9. Clutterbuck, E. J. et al. (1989) Blood 73:1504.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e10. Cameron, L. et al. (2000) J. Immunol. 164:1538.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e11. Tavernier, J. et al. (1991) Cell 66:1175.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e12. Zaks-Zilberman, M. et al. (2008) J. Biol. Chem. 283:13398.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e13. Lipscombe, R. et al. (1998) J. Leukocyte Biol. 63:342.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e14. Tavernier, J. et al. (2000) Blood 95:1600.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman IL5; hIL-5, recombinant IL5, interleukin 5, EDF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP05113\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"2\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL5 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIle20-Ser134\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e13 kDa (Monomer)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eForm\/Structure\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDimer in solution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"2\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured in a cell proliferation assay using TF-1 human erythroleukemic cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 0.04-0.2 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL5_sds_480x480.jpg?v=1754467563\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL5_Gel_filtration_480x480.jpg?v=1754467563\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL5_Bioactivity_480x480.jpg?v=1754467563\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP250.pdf?v=1754468154\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL5\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241368682677,"sku":"RP250-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241368715445,"sku":"RP250-50UG","price":464.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241368748213,"sku":"RP250-1MG","price":3708.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_24166a66-9c88-418a-ad16-e12f4d6840ae.jpg?v=1750428237"},{"product_id":"human-prothrombin","title":"Human Prothrombin","description":"Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the clotting process. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions (1-2).","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241368912053,"sku":"RP606-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241368944821,"sku":"RP606-50UG","price":598.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241368977589,"sku":"RP606-1MG","price":5768.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_f0a64464-c06b-475d-8a23-26dd222d5de0.jpg?v=1750428247"},{"product_id":"human-il17a","title":"Human IL17A","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin-17A (IL-17A) , also known as CTLA-8, is a 15-20 kDa glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded by separate genes but adopt a conserved cystine knot fold (1, 2). Mature human IL-17A shares 60% amino acid sequence identity with mouse and rat IL-17A (3, 4). IL-17A is secreted by Th17 cells, gamma \/δ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells (2). It forms disulfide-linked homodimers as well as disulfide-linked heterodimers with IL-17F (5, 6). IL-17A exerts its effects through the transmembrane IL-17RA in complex with IL-17RC or IL-17RD (7, 8). Both IL-17RA and IL-17RC are required for responsiveness to heterodimeric IL-17A\/F (7). IL-17A promotes protective mucosal and epidermal inflammation in response to microbial infection (9-12). It induces chemokine production, neutrophil influx, and the production of antibacterial peptides (9-11). IL-17A\/F likewise induces neutrophil migration, but IL-17F does not (11). IL-17A additionally enhances the production of inflammatory mediators by rheumatoid synovial fibroblasts and contributes to TNF-alpha induced shock (4, 13). In contrast, it can protect against the progression of colitis by limiting chronic inflammation (12). IL-17A has been shown to exert either tumorigenic or anti-tumor effects (14, 15).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e1. Gaffen, S.L. (2009) Nat. Rev. Immunol. 9:556.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e2. Cua, D.J. and C.M. Tato (2010) Nat. Rev. Immunol. 10:479.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e3.Yao, Z. et al. (1995) J. Immunol. 155:5483.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e4. Fossiez, F. et al. (1996) J. Exp. Med. 183:2593.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e5. Chang, S.H. and C. Dong (2007) Cell Res. 17:435.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e6. Wright, J.F. et al. (2007) J. Biol. Chem. 282:13447.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e7. Wright, J.F. et al. (2008) J. Immunol. 181:2799.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e8. Rong, Z. et al. (2009) Cell Res. 19:208.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e9. Cho, J.S. et al. (2010) J. Clin. Invest. 120:1762.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e10. Liang, S.C. et al. (2006) J. Exp. Med. 203:2271.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e11. Liang, S.C. et al. (2007) J. Immunol. 179:7791.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e12. O’Connor Jr., W. et al. (2009) Nat. Immunol. 10:603.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e13. Takahashi, N. et al. (2008) J. Exp. Med. 205:1755.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e14. Wang, L. et al. (2009) J. Exp. Med. 206:1457.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e15. Kryczek, I. et al. (2009) Blood 114:357.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman IL17A; hIL-17A, recombinant IL17A, interleukin 17A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eQ16552\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"2\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL17A protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eGly24-Ala155\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e15.1 kDa (Monomer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eForm\/Structure\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDimer in solution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"2\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe ED50 for this effect is 1.0-7.5 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL17_sds_480x480.jpg?v=1754560229\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL17_Gel_filtration_480x480.jpg?v=1754560230\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL17_Bioactivity_480x480.jpg?v=1754560230\"\u003e\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP330.pdf?v=1754559516\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL17A\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241369141429,"sku":"RP330-10UG","price":155.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241369174197,"sku":"RP330-50UG","price":371.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241369206965,"sku":"RP330-1MG","price":3070.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_262018bb-bfd3-41e8-b6d3-f0af1771ea54.jpg?v=1750428257"},{"product_id":"human-il4","title":"Human IL4","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a secreted protein that belongs to the IL-4 \/ IL-13 family (1-3). It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four α-helix structure (4). Mature human IL-4 shares 55%, 39% and 43% aa sequence identity with bovine, mouse, and rat IL-4, respectively. Human, mouse, and rat IL-4 are species-specific in their activities (5-7). IL-4 exerts its effectsthrough two receptor complexes (8, 9). The type I receptor, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 Rα and thecommon γ chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 Rα and IL-13 Rα1.The type II receptor also transduces IL-13 mediated signals. IL-4 is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils (1, 2). Itpromotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naive CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells (10-13).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e1. Benczik, M. and S.L. Gaffen (2004) Immunol. Invest. 33:109. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e2. Chomarat, P. and J. Banchereau (1998) Int. Rev. Immunol. 17:1. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e3. Yokota, T. et al. (1986) Proc. Natl. Acad. Sci. 83:5894. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e4. Redfield, C. et al. (1991) Biochemistry 30:11029. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e5. Ramirez, F. et al. (1988) J. Immunol. Meth. 221:141. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e6. Leitenberg, D. and T.L. Feldbush (1988) Cell. Immunol. 111:451. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e7. Mosman, T.R. et al. (1987) J. Immunol. 138:1813.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e8. Mueller, T.D. et al. (2002) Biochim. Biophys. Acta 1592:237. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e9. Nelms, K. et al. (1999) Annu. Rev. Immunol. 17:701.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e10. Paludan, S.R. (1998) Scand. J. Immunol. 48:459.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e11. Corthay, A. (2006) Scand. J. Immunol. 64:93.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e12. Ryan, J.J. et al. (2007) Crit. Rev. Immunol. 27:15.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e13. Grone, A. (2002) Vet. Immunol. Immunopathol. 88:1.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003cbr\u003e\n\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman IL4; hIL-4, recombinant IL4, interleukin 4, BCGF1 Protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP05112\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL4 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHis25-Ser153\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e15 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured in a cell proliferation assay using TF-1 human erythroleukemic cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 0.02-0.1 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL4_sds_480x480.jpg?v=1754465764\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL4_Gel_filtration_480x480.jpg?v=1754465764\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL4_Bioactivity_480x480.jpg?v=1754465764\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP240.pdf?v=1754465041\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL4\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241369567413,"sku":"RP240-10UG","price":227.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241369600181,"sku":"RP240-50UG","price":567.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241369632949,"sku":"RP240-1MG","price":4738.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_9311cedf-6bd5-417b-b3a1-53c9eb0c8d29.jpg?v=1750428267"},{"product_id":"human-tgfb1","title":"Human TGFb1","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\n\u003cp\u003eTGF-β1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-β superfamily that share a characteristic cystine knot structure (1–7). TGF-β1, -2, and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation, and epithelial–mesenchymal transition (1–4). Each TGF-β isoform has some non-redundant functions; for TGF-β1, mice with targeted deletion show defects in hematopoiesis and endothelial differentiation, and die of overwhelming inflammation (2).\u003c\/p\u003e\n\u003cp\u003eHuman TGF-β1 cDNA encodes a 390 amino acid (aa) precursor that contains a 29 aa signal peptide and a 361 aa proprotein (8). A furin-like convertase processes the proprotein to generate an N-terminal 249 aa latency-associated peptide (LAP) and a C-terminal 112 aa mature TGF-β1 (8, 9). Disulfide-linked homodimers of LAP and TGF-β1 remain non-covalently associated after secretion, forming the small latent TGF-β1 complex (8–10). Covalent linkage of LAP to one of three latent TGF-β binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix (9, 10). TGF-β is activated from latency by pathways that include the actions of protease plasmin, matrix metalloproteases, thrombospondin-1, and a subset of integrins (10).\u003c\/p\u003e\n\u003cp\u003eMature human TGF-β1 shares 100% aa identity with pig, dog, and cow TGF-β1, and 99% aa identity with mouse, rat, and horse TGF-β1. It demonstrates cross-species activity (1). TGF-β1 signaling begins with high-affinity binding to a type II ser\/thr kinase receptor termed TGF-βRII. This receptor then phosphorylates and activates a second ser\/thr kinase receptor, TGF-βRI (also called activin receptor-like kinase [ALK]-5), or alternatively, ALK-1. This complex phosphorylates and activates Smad proteins that regulate transcription (3, 11, 12). Contributions of the accessory receptors betaglycan (also known as TGF-βRIII) and endoglin, or use of Smad-independent signaling pathways, allow for disparate actions observed in response to TGF-β in different contexts (11).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp\u003e1.Derynck, R. and K. Miyazono (2008) Cold Spring Harbor Laboratory Press p. 29.\u003c\/p\u003e\n\u003cp\u003e2.Dunker, N. and K. Krieglstein (2000) Eur. J. Biochem. 267:6982.\u003c\/p\u003e\n\u003cp\u003e3.Wahl, S.M. (2006) Immunol. Rev. 213:213.\u003c\/p\u003e\n\u003cp\u003e4.Chang, H. et al. (2002) Endocr. Rev. 23:787.\u003c\/p\u003e\n\u003cp\u003e5.Lin, J.S. et al. (2006) Reproduction 132:179.\u003c\/p\u003e\n\u003cp\u003e6.Hinck, A.P. et al. (1996) Biochemistry 35:8517.\u003c\/p\u003e\n\u003cp\u003e7.Mittl, P.R.E. et al. (1996) Protein Sci. 5:1261.\u003c\/p\u003e\n\u003cp\u003e8.Derynck, R. et al. (1985) Nature 316:701.\u003c\/p\u003e\n\u003cp\u003e9.Miyazono, K. et al. (1988) J. Biol. Chem. 263:6407.\u003c\/p\u003e\n\u003cp\u003e10.Oklu, R. and R. Hesketh (2000) Biochem. J. 352:601.\u003c\/p\u003e\n\u003cp\u003e11.de Caestecker, M. et al. (2004) Cytokine Growth Factor Rev. 15:1.\u003c\/p\u003e\n\u003cp\u003e12.Zuniga, J.E. et al. (2005) J. Mol. Biol. 354:1052.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eTGF-beta 1 protein; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1; transforming growth factor beta-1; transforming growth factor, beta 1.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP01137.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHEK293\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAla279-Ser390\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12.8kDa(monomer)\u003cbr\u003e25.6kDa(Dimer)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile 20 mM sodium citrate(pH=2.5) buffer .\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage. \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured by the(CAGA)\u003csub\u003e12\u003c\/sub\u003e-luciferase reporter assay.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 25 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_TGFb1_SDS-PAGE.jpg?v=1755499466\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_TGFb1_Bioactivity.jpg?v=1755499465\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP510.pdf?v=1755499324\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman TGFb1\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241369829557,"sku":"RP510-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241369862325,"sku":"RP510-50UG","price":598.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241369895093,"sku":"RP510-1MG","price":5768.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_b14fa6de-852e-4b3c-b04e-5f633dcf280a.jpg?v=1750428278"},{"product_id":"human-il3","title":"Human IL3","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin-3 (IL-3) is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3\/IL-3 also belongs to the group of interleukins Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3\/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3\/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e1. Meyer CG, et al. (2011) Hum Mol Genet. 20(6):1173-81.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e2. Zambrano A, et al. (2010) Curr Alzheimer Res. 7(7):615-24.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e3. Dentelli P, et al. (2011) Oncogene. 30(50):4930-40.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman IL3; IL3; IL-3; recombinant IL3; interleukin-3; Mast cell growth factor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAAC08706\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL3 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAla20-Phe152\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e15.1 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured in a cell proliferation assay using TF-1 human erythroleukemic cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 0.01-0.08 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL3_sds_c300b809-4d3b-4620-b747-7fdbc8351670_480x480.jpg?v=1754464954\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL3_Gel_filtration_146c27d0-39ae-4522-bf1e-fa2fe086ad3c_480x480.jpg?v=1754464607\" style=\"margin-bottom: 16px; float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL3_Bioactivity_480x480.jpg?v=1754462319\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP230.pdf?v=1754465030\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL3\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241370255541,"sku":"RP230-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241370288309,"sku":"RP230-50UG","price":371.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241370321077,"sku":"RP230-1MG","price":3070.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_269f598b-fdd9-4113-af3f-6ab6224da1c9.jpg?v=1750428286"},{"product_id":"human-il2","title":"Human IL2","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin-2 (IL2),also known as a T-cell growth factor, TCGF, and Aldesleukin, is a secreted protein that belongs to the IL-2 family. IL2 has potent stimulatory activity for antigen-activated T cells, and is expressed by T cells, B cells, dendritic cells, and eosinophils (1-3). Mature human IL-2 shares 56% aa sequence identity with mouse IL-2. Human and mouse IL-2 exhibit cross-species activity (4). The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes (5-7). The 55 kDa IL-2 R alpha is specific for IL-2 and binds with low affinity. The 75 kDa IL-2R beta, which is also a component of the IL-15 receptor, binds IL-2 with intermediate affinity. The 64 kDa common gamma chain gamma c\/IL-2 R gamma, which is shared with the receptors for IL-4, -7, -9, -15, and -21, does not independently interact with IL-2. Upon ligand binding, signal transduction is performed by both IL-2 R beta and gamma c. IL-2 is best known for its autocrine and paracrine activity on T cells. It drives resting T cells to proliferate and induces IL-2 and IL-2 R alpha synthesis (1, 2). It contributes to T cell homeostasis by promoting the Fas-induced death of naive CD4+ T cells but not activated CD4+ memory lymphocytes (8). IL-2 plays a central role in the expansion and maintenance of regulatory T cells, although it inhibits the development of Th17 polarized cells (9-11). Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity (12, 13).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e1. Ma, A. et al. (2006) Annu. Rev. Immunol. 24:657. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e2. Gaffen, S.L. and K.D. Liu (2004) Cytokine 28:109. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e3. Taniguchi, T. et al. (1983) Nature 302:305. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e4. Mosmann, T.R. et al. (1987) J. Immunol. 138:1813. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e5. Liparoto, S.F. et al. (2002) Biochemistry 41:2543. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e6. Wang, X. et al. (2005) Science 310:1159. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e7. Bodnar, A. et al. (2008) Immunol. Lett. 116:117.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e8. Jaleco, S. et al. (2003) J. Immunol. 171:61. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e9. Malek, T.R. (2003) J. Leukoc. Biol. 74:961. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e10. Laurence, A. et al. (2007) Immunity 26:371. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e11. Kryczek, I. et al. (2007) J. Immunol. 178:6730. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e12. Afzali, B. et al. (2007) Clin. Exp. Immunol. 148:32. \u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e13. Fehervari, Z. et al. (2006) Trends Immunol. 27:109.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003cbr\u003e\n\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman IL2; IL-2; IL-2; IL2; interleukin-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP60568\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL2 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAla21-Thr153\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e15.4 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer to a concentration of 0.2 mg\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 0.05-0.25 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL2_SDS_480x480.jpg?v=1754461175\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL2_Gel_filtration_480x480.jpg?v=1754461269\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL2_Bioactivity_480x480.jpg?v=1754461175\"\u003e\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP220.pdf?v=1754461320\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL2\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241370484917,"sku":"RP220-10UG","price":124.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241370517685,"sku":"RP220-50UG","price":289.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241370550453,"sku":"RP220-1MG","price":1010.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_e479aeb3-8de1-4170-98c5-7efe39b6ce99.jpg?v=1750428297"},{"product_id":"human-tgfb3","title":"Human TGFb3","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eTGF-beta 3 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure . TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition . Each TGF-beta isoform has some non‑redundant functions; .Human TGF‑ beta 3 cDNA encodes a 412 amino acid (aa) precursor that contains a 23 aa signal peptide and a 389 aa proprotein . A furin‑like convertase processes the proprotein to generate an N‑terminal 277 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 3 (1-5).\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor, beta 3.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP10600.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"2\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHEK293\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAla301-Ser412\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12.7 kDa (monomer)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile 20 mM sodium citrate(pH=2.5) buffer .\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buers. Centrifuge the via prior to opening\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 as supplied\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse; height: 90px;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003e≥95%, determined by SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 36px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\"\u003e＜0.10 EU per 1 ug of the protein by the LAL method\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 36px;\" rowspan=\"2\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eMeasured by the(CAGA) 12-luciferase reporter assay.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18px;\"\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle; height: 18px;\"\u003eThe EC50 for this effect is 0.29ng\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_TGFb3_SDS-PAGE.jpg?v=1755501824\"\u003e\u003c\/p\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_TGFb3_Bioactivity.jpg?v=1755501823\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP530.pdf?v=1755501502\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman TGFb3\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241370714293,"sku":"RP530-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241370747061,"sku":"RP530-50UG","price":567.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241370779829,"sku":"RP530-1MG","price":4738.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_3839e394-8aaf-48cb-92af-46b45da84470.jpg?v=1750428307"},{"product_id":"human-il10","title":"Human IL10","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin 10 ,also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 family of alpha -helical cytokines that also includesIL-19, IL-20, IL-22, IL-24, and IL-26\/AK155 (1, 2). IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts (2-5). Mature human IL-10 shares 72%-86% amino acid sequence identity with bovine, canine, equine, feline, mouse, ovine, porcine, and rat IL-10. Whereas human IL-10 is active on mouse cells, mouse IL-10 does not act on human cells (6, 7). IL-10 is a 178 amino acid molecule that contains two intrachain disulfide bridges and is expressed as a 36 kDa noncovalently associated homodimer (6, 8, 9). The IL-10 dimer binds to two IL-10 R alpha \/IL-10 R1 chains, resulting in recruitment of two IL-10 R beta \/IL-10 R2 chains and activation of a signaling cascade involving JAK1, TYK2, and STAT3 (10). IL-10 R beta does not bind IL-10 by itself but is required for signal transduction (1). IL-10 R beta also associates with IL-20 R alpha, IL-22R alpha, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29(11-13). IL-10 is a critical molecule in the control of viral infections and allergic and autoimmune inflammation (14-16). It promotes phagocytic uptake and Th2 responses but suppresses antigen presentation and Th1 proinflammatory responses (2).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e1. Pestka, S. et al. (2004) Annu. Rev. Immunol. 22:929.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e2. Sabat, R. et al. (2010) Cytokine Growth Factor Rev. 21:331.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e3. Mathurin, P. et al. (2002) Am. J. Physiol. Gastrointest. Liver Physiol. 282:G981\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e4. Grewe, M. et al. (1995) J. Invest. Dermatol. 104:3.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e5. Szony, B.J. et al. (1999) Mol. Hum. Reprod. 5:1059.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e6. Vieira, P. et al. (1991) Proc. Natl. Acad. Sci. 88:1172.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e7. Hsu, D.-H. et al. (1990) Science 250:830.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e8. Windsor, W.T. et al. (1993) Biochemistry 32:8807.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e9. Syto, R. et al. (1998) Biochemistry 37:16943.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e10. Kotenko, S.V. et al. (1997) EMBO J. 16:5894.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e11. Kotenko, S.V. et al. (2000) J. Biol. Chem. 276:2725.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e12. Hor, S. et al. (2004) J. Biol. Chem. 279:33343.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e13. Sheppard, P. et al. (2003) Nat. Immunol. 4:63.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e14. Fitzgerald, D.C. et al. (2007) Nat. Immunol. 8:1372.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e15. Wu, K. et al. (2007) Cell. Mol. Immunol. 4:269.\u003c\/p\u003e\n\u003cp style=\"padding-left: 40px;\"\u003e16. Blackburn, S.D. and E.J. Wherry (2007)Trends Microbiol. 15:143.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eCSIF; CSIFMGC126450; Cytokine synthesis inhibitory factor; GVHDS; IL10; IL-10; IL10A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP22301\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL-10 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSer19-Asn178\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e18.6 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured in a cell proliferation assay using MC\/9-2 mouse mast cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 50-150 pg\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL10_sds_480x480.jpg?v=1754554455\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL10_Gel_filtration_480x480.jpg?v=1754554456\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL10_Bioactivity_480x480.jpg?v=1754554456\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP300.pdf?v=1754553191\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL10\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241371009205,"sku":"RP300-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241371041973,"sku":"RP300-50UG","price":639.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241371074741,"sku":"RP300-1MG","price":5356.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_c13471bb-4e12-4ed1-8b95-19fb0685e991.jpg?v=1750428322"},{"product_id":"human-tgfb2","title":"Human TGFb2","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eTGF-beta 2 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure . TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition . Each TGF-beta isoform has some non‑redundant functions; the TGFB2 gene, which encodes transforming growth factor β2 (TGFβ2), making it an obvious candidate gene for this aneurysm phenotype with MFS- and LDS-like features.Human TGF‑ beta 2 cDNA encodes a 414 amino acid (aa) precursor that contains a 20 aa signal peptide and a 394 aa proprotein . A furin‑like convertase processes the proprotein to generate an N‑terminal 282 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 2 (1-5).\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eBSC-1 cell growth inhibitor; cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; MGC116892; polyergin; TGFB2; TGFbeta 2; TGF-beta 2; TGF-beta2; TGF-beta-2; transforming growth factor beta-2; transforming growth factor, beta 2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP61812\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHEK293\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAla303-Ser414\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12.7 kDa (monomer)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile 20 mM sodium citrate(pH=2.5) buffer .\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70℃ as supplied\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e＜0.10 EU per 1 ug of the protein by the LAL method\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured by the(CAGA)\u003csub\u003e12\u003c\/sub\u003e-luciferase reporter assay\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 0.69ng\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_TGFb2_SDS-PAGE.jpg?v=1755501260\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_TGFb2_Bioactivity.jpg?v=1755501259\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP520.pdf?v=1755501345\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman TGFb2\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241398436021,"sku":"RP520-10UG","price":204.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241398468789,"sku":"RP520-50UG","price":567.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241398501557,"sku":"RP520-1MG","price":4738.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_720cb941-75c2-42bc-80fb-9afbd9c2d083.jpg?v=1750429400"},{"product_id":"human-il12","title":"Human IL12","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eInterleukin-12 (IL-12) , also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines (1). The p40 subunit of IL-12 has been shown to have extensive amino acid sequence homology to the extracellular domain of the human IL-6 receptor while the p35 subunit shows distant but significant sequence similarity to IL-6, G-CSF, and chicken MGF (2, 3). These observations have led to the suggestion that IL-12 might have evolved from a cytokine\/soluble receptor complex. Human and murine IL-12 share 70% and 60% amino acid sequence homology in their p40 and p35 subunits, respectively. IL-12 apparently shows species specificity with human IL-12 reportedly showing minimal activity in the murine system. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and natural killer (NK) cells (4). These effects include inducing production of IFN-r and TNF by resting and activated T and NK cells, synergizing with other IFN-gamma inducers at both the transcriptional and post-transcriptional levels. This interaction induces IFN-gamma gene expression, enhancing the cytotoxic activity of resting NK and T cells, inducing and synergizing with IL-2 in the generation of lymphokine-activated killer (LAK) cells, acting as a co-mitogen to stimulate proliferation of resting T cells, and inducing proliferation of activated T and NK cells (5). Current evidence indicates that IL-12, produced by macrophages in response to infectious agents, is a central mediator of the cell-mediated immune response by its actions on the development, proliferation, and activities of TH1 cells. In its role as the initiator of cell-mediated immunity, it has been suggested that IL-12 has therapeutic potential as a stimulator of cell-mediated immune responses to microbial pathogens, metastatic cancers, and viral infections such as AIDS.\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp\u003e1. Gubler, U. et al. (1991) Proc. Natl. Acad. Sci. 88:4143.\u003c\/p\u003e\n\u003cp\u003e2. Gearing, D. et al. (1991) Cell 66:9.\u003c\/p\u003e\n\u003cp\u003e3. Merberg, D. et al. (1992) Immunology Today 13:78.\u003c\/p\u003e\n\u003cp\u003e4. Wolf, S.F. et al. (1991) Journal of Immunology 146:3074.\u003c\/p\u003e\n\u003cp\u003e5. Airoldi, I. et al. (2000) Journal of Immunology 165:6880.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman IL12; hIL-12, recombinant IL12, interleukin 12\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eP29460 (IL-12p40), P29459 (IL-12p35)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human IL12 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIL-12 p40 (Ile23-Ser328), IL-12 p35 (Arg23-Ser219)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e22.5 kDa + 34.7 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable style=\"width: 90%; border-collapse: collapse;\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\" rowspan=\"3\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured in a cell proliferation assay using PHA-stimulated human T lymphoblasts.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 4-40 pg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL12_sds_480x480.jpg?v=1754556435\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eGel filtration \u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL12_Gel_filtration_480x480.jpg?v=1754556435\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cdiv style=\"text-align: start;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_IL12_Bioactivity_480x480.jpg?v=1754556435\" alt=\"\" style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP305.pdf?v=1754556483\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eHuman IL12\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241398665397,"sku":"RP305-10UG","price":289.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241398698165,"sku":"RP305-50UG","price":1010.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241398730933,"sku":"RP305-1MG","price":6798.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_ad4d552e-405c-4ce4-b159-83d560538c11.jpg?v=1750429408"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/collections\/Recombinant_Protein.png?v=1741706875","url":"https:\/\/biofargo.com\/collections\/recombinant-proteins.oembed?page=7","provider":"Biofargo","version":"1.0","type":"link"}