{"title":"Organoid Culture","description":"","products":[{"product_id":"recombinant-human-vitronectin-protein","title":"Recombinant Human Vitronectin Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:920px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\n \/* =========================\n Data Figures (image card)\n ========================== *\/\n .biofargo-figure-card{\n text-align:center;\n margin-top:20px;\n border:1px solid #eee;\n padding:15px;\n border-radius:8px;\n background:#fff;\n }\n .biofargo-figure-card img{\n max-width:100%;\n height:auto;\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eThe recombinant human Vitronectin (VTN) protein is a high-purity multifunctional glycoprotein transiently expressed in HEK-293 cells, featuring a C-terminal polyhistidine tag for precise purification via nickel-affinity chromatography.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eAs a core component of the extracellular matrix (ECM), vitronectin mediates cell adhesion, spreading, and migration through RGD sequence-specific binding to integrin receptors (αvβ3, αvβ5, αvβ1, etc.), while regulating stem cell proliferation and differentiation.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIn cell and gene therapy applications, this protein serves as a critical element in serum-free culture systems: its multimeric form efficiently incorporates into biomimetic scaffolds, providing in vivo-like adhesion signals for mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) to significantly enhance ex vivo expansion efficiency and stemness maintenance.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eFurthermore, it synergizes with growth factors (e.g., TGF-β) to optimize microenvironments for organoid development and tissue-engineered grafts, promoting vascularized tissue regeneration.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eThe native conformation ensures its full bioactivity.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:25%;\"\u003eParameter\u003c\/th\u003e\n \u003cth style=\"width:37.5%;\"\u003eSpecification\u003c\/th\u003e\n \u003cth class=\"center\" style=\"width:37.5%;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried preparation, the form should be white loose body\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eIdentity\u003c\/td\u003e\n \u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eVisible Particle\u003c\/td\u003e\n \u003ctd\u003eShould be no visible particle\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMoisture\u003c\/td\u003e\n \u003ctd\u003e≤4.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e2.29%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003epH\u003c\/td\u003e\n \u003ctd\u003e6.5~7.5\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e7.01\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;95.0%\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMycoplasma\u003c\/td\u003e\n \u003ctd\u003eShould be negative\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNegative\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eNo growth\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eBy measuring its ability to promote hiPS cell adhesion, this effect ED50 \u0026lt; 2.4 μg\/mL\u003c\/td\u003e\n \u003ctd class=\"center\"\u003e1.139 μg\/mL\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHEK293-Expressed His-Tagged Vitronectin\u003c\/strong\u003e\n \u003cp\u003eRecombinant human vitronectin (Asp19–Leu478) expressed in HEK293 cells with a C-terminal 6×His-tag, predicted molecular weight 53 kDa.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity and Quality Compliance\u003c\/strong\u003e\n \u003cp\u003ePurity \u0026gt;95.0% with electrophoretic identity consistent with the expected molecular weight; no visible particles; moisture 2.29%; pH 7.01 within 6.5–7.5 specification.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eLow Endotoxin and Sterility Assurance\u003c\/strong\u003e\n \u003cp\u003eEndotoxin level \u0026lt;0.1 EU\/µg (LAL method), mycoplasma negative, and sterility confirmed with no growth.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eValidated hiPS Cell Adhesion Activity\u003c\/strong\u003e\n \u003cp\u003eBiological activity determined by promotion of hiPS cell adhesion with ED₅₀ ≤2.4 µg\/mL (measured 1.139 µg\/mL).\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003ehiPS Cell Adhesion Support\u003c\/h4\u003e\n \u003cp\u003ePromotes adhesion of human induced pluripotent stem (hiPS) cells for in vitro culture applications.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eSerum-Free Stem Cell Culture\u003c\/h4\u003e\n \u003cp\u003eFunctions as a defined extracellular matrix component supporting MSC and iPSC expansion and stemness maintenance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eCell Culture Surface Coating\u003c\/h4\u003e\n \u003cp\u003eUsed for coating culture plates to enhance cell attachment via integrin-mediated interactions.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eOrganoid and Tissue Engineering\u003c\/h4\u003e\n \u003cp\u003eSupports microenvironment optimization in organoid development and tissue-engineered graft studies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Data Figures --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eData Figures\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-figure-card\"\u003e\n \u003cimg alt=\"Recombinant Human Vitronectin (VTN) Protein\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/gmp-tl651-2_600x600.jpg?v=1748505222\"\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left:20px; margin:10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Stable for 24 months at -20°C when stored in the original sealed container under desiccant.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eReconstitution: For lyophilized powder, dissolve in sterile water for injection, 0.9% NaCl, or PBS (pH7.4), maintaining a final concentration ≥100 µg\/mL to prevent adsorption.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eHandling: Aliquot to avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-caution\"\u003e\n \u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Prepare solutions using sterile technique. Avoid microbial contamination to maintain activity.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Storage:\u003c\/strong\u003e Follow recommended storage conditions. Repeated freeze–thaw cycles may reduce performance.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_Vitronectin_Protein.pdf?v=1772506061\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL651 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_Vitronectin_Protein.pdf?v=1772506061\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL651 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-PrTE2505010-GMP-TL651-0100.pdf?v=1772506063\" target=\"_blank\" rel=\"noopener\"\u003e📄 GMP-TL651 COA\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"100μg","offer_id":43214503248053,"sku":"GMP-TL651-0100","price":235.0,"currency_code":"USD","in_stock":true},{"title":"1000μg","offer_id":45422806204597,"sku":"GMP-TL651L-1000","price":270.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-GMP-TL651-0100.png?v=1772505947"},{"product_id":"nicotinamide","title":"Nicotinamide","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eNicotinamide (NAM) belongs to vitamin B family and is the amide form of vitamin B3. NAM is present in food and is a constituent of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Tryptophan is the precursor for NAM synthesis in liver.[1] NAM controls cell metabolism, redox reactions, mitochondrial functionsand energy generation. It promotes natural killer cells proliferation and survival.[2] NAM confers neuroprotection and promotes neuronal maturation. It has the ability to cross the blood-brain barrier and may provide protection in ischaemic stroke and traumatic brain injury. NAM may elicit therapeutic benefits in Alzheimer′s, Parkinson′s, and Huntington′s diseases.\u003c\/p\u003e\n\u003ch2\u003eSpecification\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eGrade\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eReagent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormula\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eC\u003csub\u003e6\u003c\/sub\u003eH\u003csub\u003e6\u003c\/sub\u003eN\u003csub\u003e2\u003c\/sub\u003eO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMW\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e122.1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eCAS\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003e98-92-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eAppearance\u003c\/td\u003e\n\u003ctd style=\"width: 50%; height: 3px; text-align: center; vertical-align: middle;\"\u003eWhite crystalline or powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIdentification\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eComplies\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMelting Point\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e128 - 131℃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eLoss on Drying\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e≤0.5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eResidue on ignition\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e≤0.1%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHeavy Metals\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e≤0.003%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eReadily carbonizable substances\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e≤ Control Solution A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eOrganic volatile impurities\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eComplies\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eResidual solvents\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eComplies\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAssay\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e98.5-101.5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e18~25℃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eApplication\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003eNicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells, esophageal squamous cell carcinomas(ESCC), pancreatic cancer organoids and pancreatic progenitor induction.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA.NB0659-NO_LOT.pdf?v=1747467504\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eCOA\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS_NB0659-Niacinamide.pdf?v=1747467504\" type=\"application\/pdf\" target=\"_blank\"\u003e\u003cstrong\u003eSDS\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"BioBasic","offers":[{"title":"250g","offer_id":45388545851573,"sku":"NB0659-250g","price":41.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Nicotinamide.jpg?v=1747466974"},{"product_id":"human-r-spondin-1","title":"Human R-Spondin 1","description":"\u003ch2\u003eBcakground\u003c\/h2\u003e\n\u003cp\u003eR-Spondin 1 (RSPO1), also known as cysteine-rich and single thrombospondin domain containing protein 3 (Cristin 3), is a 27 kDa secreted protein that shares ~40% amino acid (aa) identity with three other R-Spondin family members (1, 2). All R-Spondins regulate Wnt\/ beta-Catenin signaling but have distinct expression patterns (1-3). Human R-Spondin 1 (aa21-263) shares 89%, 87%, 92%, 91%, 91% and 89% aa identity with mouse, rat, horse, dog, goat, and cow RSPO-1, respectively. R-Spondin 1 competes with the Wnt antagonist DKK-1 for binding to the Wnt co-receptors, Kremen and LRP-6, reducing their DKK-1-mediated internalization (4). However, reports are mixed on whether R-Spondin 1 binds LRP-6 directly (4-6). R-Spondin 1 is expressed in early development at the roof plate boundary and is thought to contribute to dorsal neural tube development (3, 7). Interest in R-Spondin 1 as a cell culture supplement has grown with the expansion of the organoid field. R-Spondin 1 is widely used in organoid cell culture workflows as a vital component that promotes both growth and survival of 3D organoids (8). Structurally similar to other R-Spondins, R-Spondin 1 contains two adjacent cysteine-rich furin-like domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP-1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furin-like domains are needed for beta-catenin stabilization (2, 9). A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus (10). Potential isoforms of 200 and 236 aa have an alternate, shorter N-terminus or are missing aa 146-208, respectively (11).\u003c\/p\u003e\n\u003ch2\u003eReference\u003c\/h2\u003e\n\u003cp\u003e1. Chen, J-Z. et al. (2002) Mol. Biol. Rep. 29:287.\u003c\/p\u003e\n\u003cp\u003e2. Kim, K.-A. et al. (2006) Cell Cycle 5:23.\u003c\/p\u003e\n\u003cp\u003e3. Nam, J.-S. et al. (2007) Gene Expr. Patterns 7:306.\u003c\/p\u003e\n\u003cp\u003e4. Binnerts, M.E. et al. (2007) Proc. Natl. Acad. Sci. USA 104:14700.\u003c\/p\u003e\n\u003cp\u003e5. Nam, J.-S. et al. (2006) J. Biol. Chem. 281:13247.\u003c\/p\u003e\n\u003cp\u003e6. Wei, Q. et al. (2007) J. Biol. Chem. 282:15903.\u003c\/p\u003e\n\u003cp\u003e7. Kamata, T. et al. (2004) Biochim. Biophys. Acta 1676:51.\u003c\/p\u003e\n\u003cp\u003e8. Drost and Clevers. (2018) Nature Reviews Cancer 18:407.\u003c\/p\u003e\n\u003cp\u003e9. Kazanskaya, O. et al. (2004) Dev. Cell 7:525.\u003c\/p\u003e\n\u003cp\u003e10. Tomaselli, S. et al. (2008) Hum. Mutat. 29:220.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eCristin 3; HRspo1; roof plate-specific spondin; RSPO1; RSpondin 1; R-Spondin 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAccession #\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eQ2MKA7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSource\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eHuman embryonic kidney cell, HEK293-derived human R-Spondin 1 protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSer21-Ala263\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePredicted Moleucular weight\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e25.6 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eComponents and Storage\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eSolution protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eDissolved in sterile PBS buffer.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThis solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"3\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eStorage and Stability\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eAvoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eIt is recommended that the protein be aliquoted for optimal storage.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e12 months from date of receipt, -20 to -70 °C as supplied.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eShipping with dry ice\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eQuality\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"width: 90%; border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026gt; 95%, determined by SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eEndotoxin Level\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003e\u0026lt;0.010 EU per 1 ug of the protein by the LAL method\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd rowspan=\"2\" style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eActivity\u003c\/td\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eMeasured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 50%; text-align: center; vertical-align: middle;\"\u003eThe EC50 for this effect is 1-10 ng\/mL in the presence of 5 ng\/mL Recombinant Mouse Wnt-3a .\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eSDS-PAGE\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_R-Spondin_1_SDS-PAGE.jpg?v=1755080686\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eBioactivity\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Human_R-Spondin_1_Bioactivity.jpg?v=1755080686\" alt=\"\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/RP618.pdf?v=1755080728\" type=\"application\/pdf\" target=\"_blank\"\u003eHuman R-Spondin 1\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Bostonmolecules","offers":[{"title":"10ug","offer_id":51241453748405,"sku":"RP618-10UG","price":307.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":51241453781173,"sku":"RP618-50UG","price":804.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":51241453813941,"sku":"RP618-1MG","price":5768.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/HumanIL1a_d0cbdf93-c102-42de-84e9-47f197d1d6e7.jpg?v=1750431279"},{"product_id":"amms®-organoid-specific-matrigel","title":"AMMS® Organoid-specific Matrigel","description":"\u003cstyle\u003e\n .biofargo-wrap{\n font-family:'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{margin-top:28px;}\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:860px;\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table thead th.center,\n table.biofargo-table tbody td.center{\n text-align:center;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin-bottom:14px;\n }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n @media (max-width:640px){\n .biofargo-wrap{padding:18px;}\n .biofargo-grid{grid-template-columns:1fr;}\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eAMMS® organoid-specific matrix gel is made from basement membrane components extracted from mouse tumor tissues, and its main components include laminin, type IV collagen, heparin sulfate proteoglycans, etc.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eThese components can provide the support and signals required for cell adhesion, differentiation and proliferation, and can also simulate the characteristics of basement membranes in physiological environments, thereby improving the success rate and effect of cell culture.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIn addition to basement membrane components, AMMS® organoid matrix is also rich in a variety of growth factors. These growth factors can promote cell differentiation, proliferation and migration, thereby further simulating cell signaling pathways and interactions in the physiological environment.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eAMMS® organoid matrix has a wide range of application prospects, especially in tissue engineering, cell culture and research, and can be used for organoid culture, stem cell differentiation, angiogenesis, migration or invasion, and in vivo tumorigenesis.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:25%;\"\u003eParameter\u003c\/th\u003e\n \u003cth style=\"width:37.5%;\"\u003eSpecification\u003c\/th\u003e\n \u003cth class=\"center\" style=\"width:37.5%;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eYellow jelly-like\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eProtein Concentration\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;8 mg\/mL\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eGel Time\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;30 min\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eLactic Dehydrogenase Virus (LDEV)\u003c\/td\u003e\n \u003ctd\u003ePCR-negative\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eFungi, Bacteria, Mycoplasma\u003c\/td\u003e\n \u003ctd\u003eShould be negative\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eGel Stability (37°C, 14 Days)\u003c\/td\u003e\n \u003ctd\u003eStabilize\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eStem Cell Culture\u003c\/td\u003e\n \u003ctd\u003ePotential growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eNerve Axon Culture\u003c\/td\u003e\n \u003ctd\u003ePotential growth\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;1.5 EU\/mL\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePackage\u003c\/td\u003e\n \u003ctd\u003eNo damage, no leakage\u003c\/td\u003e\n \u003ctd class=\"center\"\u003eComply with regulations\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eBasement Membrane–Derived Matrix Composition\u003c\/strong\u003e\n \u003cp\u003eComposed primarily of laminin, type IV collagen, and heparin sulfate proteoglycans, providing structural and biochemical cues similar to native basement membranes.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eGrowth Factor–Enriched Microenvironment\u003c\/strong\u003e\n \u003cp\u003eContains multiple endogenous growth factors that support cell differentiation, proliferation, migration, and intercellular signaling in three-dimensional culture systems.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eRapid Gelation for 3D Culture Systems\u003c\/strong\u003e\n \u003cp\u003eForms a stable gel within 30 minutes under appropriate conditions, enabling reliable scaffold formation for organoid embedding and culture.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Protein Concentration Matrix\u003c\/strong\u003e\n \u003cp\u003eProtein concentration greater than 8 mg\/mL provides sufficient extracellular matrix density for structural stability and cell support.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eQuality-Controlled Biological Safety\u003c\/strong\u003e\n \u003cp\u003eTested negative for LDEV, fungi, bacteria, and mycoplasma, with endotoxin levels below 1.5 EU\/mL to ensure suitability for sensitive cell culture applications.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eOrganoid Culture and Embedding\u003c\/h4\u003e\n \u003cp\u003eProvides a three-dimensional extracellular matrix scaffold for the construction and long-term culture of organoids.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eStem Cell Differentiation Studies\u003c\/h4\u003e\n \u003cp\u003eSupports differentiation of stem cells in physiologically relevant extracellular matrix conditions.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eAngiogenesis Research\u003c\/h4\u003e\n \u003cp\u003eApplicable for studying endothelial cell migration, vascular formation, and microenvironment interactions.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eCell Migration and Invasion Assays\u003c\/h4\u003e\n \u003cp\u003eSuitable for modeling tumor invasion, migration behavior, and cell–matrix interactions.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eTissue Engineering and Regenerative Biology\u003c\/h4\u003e\n \u003cp\u003eUsed in experimental systems requiring extracellular matrix simulation for tissue modeling and regenerative research.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStorage\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0;\"\u003eStore at −20 °C or −80 °C for long-term preservation. Avoid repeated freeze–thaw cycles.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-AMMS_Organoid_Matrix_Gel_Instructions.pdf?v=1773298007\" target=\"_blank\" rel=\"noopener\"\u003e📄 AS-41-5 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-AMMS_Organoid-specific_Matrigel.pdf?v=1773298007\" target=\"_blank\" rel=\"noopener\"\u003e📄 AS-41-5 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-MED2408001.pdf?v=1773298007\" target=\"_blank\" rel=\"noopener\"\u003e📄 AS-41-5 COA\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"5mL","offer_id":51379766788277,"sku":"AS-41-5","price":220.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-AS-41-5.jpg?v=1773298278"},{"product_id":"recombinant-human-bmp-4-protein","title":"Recombinant Human BMP-4 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrapper {\n overflow-x: auto;\n margin: 20px 0;\n -webkit-overflow-scrolling: touch;\n }\n\n .biofargo-spec-table {\n width: 100%;\n border-collapse: collapse;\n border: 1px solid #dee2e6;\n min-width: 720px;\n background: #fff;\n }\n\n .biofargo-spec-table th,\n .biofargo-spec-table td {\n border: 1px solid #dee2e6;\n padding: 12px;\n vertical-align: middle;\n white-space: normal;\n word-break: break-word;\n }\n\n @media (max-width: 640px) {\n .biofargo-table-wrapper {\n border: 1px solid #eee;\n border-radius: 10px;\n padding: 6px;\n background: #fff;\n }\n .biofargo-spec-table { min-width: 860px; }\n }\n\u003c\/style\u003e\n\n\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\n \u003c!-- Description --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 8px; border: 1px solid #f0f0f0;\"\u003e\n \u003cp style=\"margin: 0 0 10px 0;\"\u003eBMP-4 is a disulfide-stabilized homodimeric growth factor and core member of the Bone Morphogenetic Protein (BMP) subfamily within the TGF-β superfamily. It specifically binds type I (BMPR1A) and type II (BMPR2) receptors to activate SMAD1\/5\/8-SMAD4 signaling, precisely governing mesodermal lineage commitment, neurogenesis, and angiogenesis.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0;\"\u003eThis protein induces osteogenic differentiation of mesenchymal stem cells via Runx2\/Osterix transcriptional programs and coordinates with PTHRP to regulate mammary ductal morphogenesis and hair follicle suppression. Its activity is tightly modulated by extracellular antagonists (e.g., Noggin\/Chordin), with dysregulation linked to pathologies like Fibrodysplasia Ossificans Progressiva (FOP).\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 10px 0;\"\u003eFor cell therapy applications, BMP-4 serves as a pivotal differentiation inducer with dual functions:\u003c\/p\u003e\n \u003cul style=\"margin: 0 0 10px 18px; padding: 0;\"\u003e\n \u003cli style=\"margin-bottom: 6px;\"\u003eTemporal gradient dosing in 3D hiPSC cultures efficiently generates mesodermal progenitors for cardiac regenerative therapies;\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0;\"\u003eSynergy with ROCK inhibitors to engineer vascular networks in organoids, enhancing in vivo integration and vascularization of osteochondral grafts.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003cp style=\"margin: 0;\"\u003eProduced via mammalian cell transient transfection and chromatographic purification, this product retains native dimeric conformation and full bioactivity.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrapper\"\u003e\n \u003ctable class=\"biofargo-spec-table\"\u003e\n \u003cthead\u003e\n \u003ctr style=\"background-color: #0056b3; color: #fff;\"\u003e\n \u003cth style=\"width: 30%; text-align: left;\"\u003eSpecification\u003c\/th\u003e\n \u003cth style=\"width: 40%; text-align: left;\"\u003eAcceptance Criteria\u003c\/th\u003e\n \u003cth style=\"width: 30%; text-align: left;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried preparation; white, loose solid\u003c\/td\u003e\n \u003ctd\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eIdentity\u003c\/td\u003e\n \u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n \u003ctd\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eVisible Particles\u003c\/td\u003e\n \u003ctd\u003eNo visible particles\u003c\/td\u003e\n \u003ctd\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMoisture\u003c\/td\u003e\n \u003ctd\u003e≤ 4.0%\u003c\/td\u003e\n \u003ctd\u003e2.0%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 90.0%\u003c\/td\u003e\n \u003ctd\u003eCompliance\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU\/μg\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU\/μg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eMycoplasma\u003c\/td\u003e\n \u003ctd\u003eNegative\u003c\/td\u003e\n \u003ctd\u003eNegative\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003ctd\u003eNo growth\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\"\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003eInduction of alkaline phosphatase production in ATDC-5 cells; ED\u003csub\u003e50\u003c\/sub\u003e ≤ 100 ng\/mL\u003c\/td\u003e\n \u003ctd\u003eED\u003csub\u003e50\u003c\/sub\u003e = 12.04 ng\/mL\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n\n \u003cp\u003e \u003c\/p\u003e\n\n \u003c!-- Features --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 10px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n \u003cul style=\"list-style: none; padding: 0; margin: 0;\"\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eative Dimeric BMP-4 Activity\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eDisulfide-stabilized homodimer preserves full BMPR-SMAD1\/5\/8 signaling fidelity.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Differentiation Potency\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eStrong osteo- and mesoderm-inducing activity validated by ATDC-5 ALP assay (ED₅₀ ≈ 12 ng\/mL).\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eMammalian Expression, Tag-Free\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eHEK293 production ensures proper folding and bioactivity without tag-related interference.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0; padding-left: 30px; position: relative;\"\u003e\n \u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eExcellent Batch Consistency\u003c\/strong\u003e\n \u003cp style=\"margin: 6px 0 0 0;\"\u003eTight QC on purity, endotoxin, sterility, and mycoplasma supports reproducible differentiation outcomes.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Applications --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv style=\"display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 16px;\"\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; border-radius: 10px; padding: 14px; background: #fff;\"\u003e\n \u003ch4 style=\"margin: 0 0 6px 0; font-size: 16px; color: #333;\"\u003eMSC Osteogenic Differentiation\u003c\/h4\u003e\n \u003cp style=\"margin: 0; font-size: 14px;\"\u003eDrives Runx2\/Osterix programs for bone and osteochondral tissue engineering.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; border-radius: 10px; padding: 14px; background: #fff;\"\u003e\n \u003ch4 style=\"margin: 0 0 6px 0; font-size: 16px; color: #333;\"\u003eiPSC Mesoderm Induction\u003c\/h4\u003e\n \u003cp style=\"margin: 0; font-size: 14px;\"\u003eEnables controlled generation of mesodermal progenitors for cardiac and musculoskeletal models.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; border-radius: 10px; padding: 14px; background: #fff;\"\u003e\n \u003ch4 style=\"margin: 0 0 6px 0; font-size: 16px; color: #333;\"\u003eOrganoid \u0026amp; 3D Culture Systems\u003c\/h4\u003e\n \u003cp style=\"margin: 0; font-size: 14px;\"\u003eSynergizes with ROCK inhibitors to promote vascularized organoid formation.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv style=\"border: 1px solid #e1e8ed; border-radius: 10px; padding: 14px; background: #fff;\"\u003e\n \u003ch4 style=\"margin: 0 0 6px 0; font-size: 16px; color: #333;\"\u003eRegenerative Medicine Research\u003c\/h4\u003e\n \u003cp style=\"margin: 0; font-size: 14px;\"\u003eSupports studies in bone repair, developmental biology, and lineage specification.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left: 20px; margin: 10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eLyophilized powder: Store at −20 °C in the original sealed container to maintain stability.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 8px;\"\u003eReconstitution: Reconstitute with sterile Water for Injection, 0.9% NaCl, or PBS (pH 7.4) prior to use.\u003c\/li\u003e\n \u003cli style=\"margin-bottom: 0;\"\u003eHandling: After reconstitution, aliquot the solution and avoid repeated freeze–thaw cycles.\u003c\/li\u003e\n \u003c\/ul\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px; border-radius: 8px;\"\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Safety:\u003c\/strong\u003e Use appropriate PPE and standard laboratory safety practices when handling this product.\u003c\/p\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv style=\"display: flex; gap: 12px; margin-top: 12px; flex-wrap: wrap;\"\u003e\n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2512012-TL-607-0050.pdf?v=1772433328\" target=\"_blank\" style=\"display:inline-block; padding: 10px 18px; background:#0056b3; color:#fff; text-decoration:none; border-radius:6px; font-weight:700; font-size:14px;\"\u003e\n 📄 TL-607 COA\n \u003c\/a\u003e\n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_BMP-4_Protein.pdf?v=1772433328\" target=\"_blank\" style=\"display:inline-block; padding: 10px 18px; border:2px solid #0056b3; color:#0056b3; text-decoration:none; border-radius:6px; font-weight:700; font-size:14px;\"\u003e\n 📄 TL-607 SDS\n \u003c\/a\u003e\n \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_BMP-4_Protein.pdf?v=1772433328\" target=\"_blank\" style=\"display:inline-block; padding: 10px 18px; border:2px solid #0056b3; color:#0056b3; text-decoration:none; border-radius:6px; font-weight:700; font-size:14px;\"\u003e\n 📄 TL-607 Data Sheet\n \u003c\/a\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":51380035158197,"sku":"TL-607-0050","price":390.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-607-0050.png?v=1772433128"},{"product_id":"recombinant-human-laminin-511-e8-protein","title":"Recombinant Human Laminin-511 E8 Protein","description":"\u003cstyle\u003e\n \/* =========================\n Biofargo Product Page Base\n ========================== *\/\n .biofargo-wrap{\n font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{ margin-top:28px; }\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n\n \/* =========================\n Table Responsive\n ========================== *\/\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:820px; \/* allow horizontal scroll on mobile *\/\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n white-space:normal;\n word-break:break-word;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n\n \/* =========================\n Features (✔ list)\n ========================== *\/\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin:0 0 14px 0;\n }\n .biofargo-checklist li:last-child{ margin-bottom:0; }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-checklist strong{\n display:block;\n font-size:15px;\n margin-bottom:4px;\n }\n .biofargo-checklist p{\n margin:0;\n font-size:14px;\n }\n\n \/* =========================\n Applications (2x2 cards)\n ========================== *\/\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n @media (max-width:640px){\n .biofargo-wrap{ padding:18px; }\n .biofargo-grid{ grid-template-columns:1fr; }\n }\n\n \/* =========================\n Warning \/ Cautions\n ========================== *\/\n .biofargo-caution{\n background:#fff5f5;\n \n padding:14px;\n border-radius:10px;\n color:#852d2d;\n font-size:14px;\n }\n .biofargo-caution p{ margin:0 0 8px 0; }\n .biofargo-caution p:last-child{ margin:0; }\n\n \/* =========================\n Documents (dual CTA)\n ========================== *\/\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eLaminin-511 E8 is a recombinant truncated protein expressed in HEK-293 cells and purified via affinity chromatography, comprising the C-terminal domains of α5, β1, and γ1 chains while retaining full integrin-binding capacity.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eAs a critical component of the basement membrane, Laminin-511 E8 provides structural support for pluripotent stem cells (PSCs) through its cell-binding motifs (e.g., integrin-binding sites), significantly enhancing cell adhesion, proliferation, and undifferentiated state maintenance.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eStudies demonstrate that compared to full-length Laminin-511 or traditional matrices (e.g., Matrigel), Laminin-511 E8 exhibits superior cell adhesion efficiency and supports long-term stable passaging (\u0026gt;10 passages) of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) without karyotypic abnormalities.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eIts optimized design enables dual applications in pre-coating and direct suspension mixing methods, offering a defined and efficient solution for organoid culture and directed differentiation research.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:30%;\"\u003eSpecification\u003c\/th\u003e\n \u003cth style=\"width:40%;\"\u003eAcceptance Criteria\u003c\/th\u003e\n \u003cth style=\"width:30%;\"\u003eResults\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eSDS-PAGE\u003c\/td\u003e\n \u003ctd\u003eThe electrophoretic bands should be consistent with the molecular weight of the product\u003c\/td\u003e\n \u003ctd\u003eComplies with specifications\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eFreeze-dried powder; white, loose solid\u003c\/td\u003e\n \u003ctd\u003eComplies with specifications\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eVisible Foreign Matter\u003c\/td\u003e\n \u003ctd\u003eNo visible foreign particles\u003c\/td\u003e\n \u003ctd\u003eComplies with specifications\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMoisture Content\u003c\/td\u003e\n \u003ctd\u003e≤ 4.0%\u003c\/td\u003e\n \u003ctd\u003e0.5%\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003epH\u003c\/td\u003e\n \u003ctd\u003e6.5 – 7.5\u003c\/td\u003e\n \u003ctd\u003e7.5\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt; 90%\u003c\/td\u003e\n \u003ctd\u003eComplies with specifications\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eBacterial Endotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU\/μg\u003c\/td\u003e\n \u003ctd\u003e\u0026lt; 0.1 EU\/μg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMycoplasma\u003c\/td\u003e\n \u003ctd\u003eNegative\u003c\/td\u003e\n \u003ctd\u003eNegative\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSterility\u003c\/td\u003e\n \u003ctd\u003eNo bacterial growth\u003c\/td\u003e\n \u003ctd\u003eNo growth observed\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eBiological Activity\u003c\/td\u003e\n \u003ctd\u003ePromotes hiPSC adhesion with ED\u003csub\u003e50\u003c\/sub\u003e ≤ 5 μg\/mL; supports stable hiPSC passaging\u003c\/td\u003e\n \u003ctd\u003eED\u003csub\u003e50\u003c\/sub\u003e = 1 μg\/mL\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003cp\u003e \u003c\/p\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:8px;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eOptimized E8 Fragment Design\u003c\/strong\u003e\n \u003cp\u003eRetains full integrin-binding activity with reduced structural complexity for higher consistency than full-length laminin.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eSuperior hiPSC Adhesion Efficiency\u003c\/strong\u003e\n \u003cp\u003eDemonstrates strong cell adhesion potency (ED₅₀ ≈ 1 µg\/mL), outperforming traditional matrices such as Matrigel.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eSupports Long-Term Pluripotency\u003c\/strong\u003e\n \u003cp\u003eEnables stable maintenance and passaging (\u0026gt;10 passages) of hESCs and iPSCs without karyotypic abnormalities.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eDefined, Recombinant Matrix\u003c\/strong\u003e\n \u003cp\u003eHEK293 expression and affinity purification provide a xeno-free, well-defined substrate for reproducible stem cell culture.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eiPSC \/ hESC Maintenance\u003c\/h4\u003e\n \u003cp\u003eEnhances adhesion, proliferation, and undifferentiated state maintenance in feeder-free culture systems.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eOrganoid Culture Systems\u003c\/h4\u003e\n \u003cp\u003eSuitable for both surface coating and direct mixing methods in 3D organoid workflows.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eDirected Differentiation Studies\u003c\/h4\u003e\n \u003cp\u003eProvides a controlled extracellular matrix for lineage-specific differentiation research.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eStem Cell Manufacturing Research\u003c\/h4\u003e\n \u003cp\u003eIdeal for standardized and scalable pluripotent stem cell expansion protocols.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Stability \u0026 Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStability \u0026amp; Storage\u003c\/h2\u003e\n \u003cul style=\"padding-left:20px; margin:10px 0 0 0;\"\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eLyophilized powder: Store at −20 °C in the original sealed container.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:8px;\"\u003eHandling after reconstitution: Prepare solutions under sterile conditions. Store reconstituted protein according to experimental requirements and avoid repeated freeze–thaw cycles.\u003c\/li\u003e\n \u003cli style=\"margin-bottom:0;\"\u003eGeneral handling: Ensure solutions are free of contamination to maintain biological activity.\u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Cautions (Universal) --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eCautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-caution\"\u003e\n \u003cp\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not intended for diagnostic or therapeutic use.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Handling:\u003c\/strong\u003e Follow recommended storage and handling instructions to maintain product stability.\u003c\/p\u003e\n \u003cp\u003e\u003cstrong\u003e• Safety:\u003c\/strong\u003e Use appropriate PPE and standard laboratory safety practices when handling this product.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2410009-TL-766-0100.pdf?v=1772433571\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-766 COA\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_Laminin-511_E8_Protein.pdf?v=1772433571\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-766 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_Human_Laminin-511_E8_Protein.pdf?v=1772433571\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-766 Data Sheet\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"100μg","offer_id":51380123599029,"sku":"TL-766-0100","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-766-0100.png?v=1772434131"},{"product_id":"recombinant-human-wnt3a-protein","title":"Recombinant Human Wnt3a Protein","description":"\u003cstyle\u003e\n .biofargo-wrap{\n font-family:'Segoe UI', Roboto, Helvetica, Arial, sans-serif;\n color:#333;\n line-height:1.65;\n max-width:1000px;\n margin:0 auto;\n background:#fff;\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:28px;\n }\n .biofargo-h2{\n color:#0056b3;\n border-bottom:2px solid #0056b3;\n padding-bottom:8px;\n margin:0 0 14px 0;\n font-size:22px;\n }\n .biofargo-section{margin-top:28px;}\n .biofargo-card{\n background:#fcfcfc;\n border:1px solid #f0f0f0;\n border-radius:10px;\n padding:16px;\n }\n .biofargo-table-wrap{\n overflow-x:auto;\n -webkit-overflow-scrolling:touch;\n border:1px solid #eee;\n border-radius:10px;\n padding:6px;\n background:#fff;\n }\n table.biofargo-table{\n width:100%;\n border-collapse:collapse;\n font-size:14px;\n min-width:720px;\n background:#fff;\n }\n table.biofargo-table th,\n table.biofargo-table td{\n border:1px solid #ddd;\n padding:12px;\n vertical-align:middle;\n }\n table.biofargo-table thead th{\n background:#0056b3;\n color:#fff;\n font-weight:700;\n text-align:left;\n }\n table.biofargo-table tbody td:first-child{\n font-weight:700;\n background:#f8f9fa;\n }\n .biofargo-checklist{\n list-style:none;\n padding:0;\n margin:0;\n }\n .biofargo-checklist li{\n position:relative;\n padding-left:28px;\n margin-bottom:14px;\n }\n .biofargo-check{\n position:absolute;\n left:0;\n top:0;\n color:#0056b3;\n font-weight:800;\n }\n .biofargo-grid{\n display:grid;\n grid-template-columns:repeat(2, minmax(0, 1fr));\n gap:16px;\n }\n .biofargo-app-card{\n border:1px solid #e1e8ed;\n border-radius:12px;\n padding:14px;\n background:#fff;\n }\n .biofargo-app-card h4{\n margin:0 0 6px 0;\n font-size:16px;\n color:#333;\n }\n .biofargo-app-card p{\n margin:0;\n font-size:14px;\n }\n .biofargo-docs{\n display:flex;\n flex-wrap:wrap;\n gap:12px;\n margin-top:12px;\n }\n .biofargo-btn{\n display:inline-block;\n padding:10px 18px;\n border-radius:8px;\n font-weight:800;\n font-size:14px;\n text-decoration:none;\n }\n .biofargo-btn.primary{\n background:#0056b3;\n color:#fff;\n border:2px solid #0056b3;\n }\n .biofargo-btn.outline{\n background:#fff;\n color:#0056b3;\n border:2px solid #0056b3;\n }\n @media (max-width:640px){\n .biofargo-wrap{padding:18px;}\n .biofargo-grid{grid-template-columns:1fr;}\n }\n\u003c\/style\u003e\n\n\u003cdiv class=\"biofargo-wrap\"\u003e\n\n \u003c!-- Description --\u003e\n \u003cdiv class=\"biofargo-section\" style=\"margin-top:0;\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDescription\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eWnt3a is a member of the Wnt family and is involved in cell self-renewal, proliferation, differentiation, and cell movement.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eThe classical Wnt\/β-catenin signaling pathway is one of the most conserved pathways in evolution and plays a key role in embryonic development, cell growth, differentiation, polarity formation, neural development, and carcinogenesis.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eWnt3a is also a commonly used cytokine in organoid culture.\u003c\/p\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eIn the culture of intestinal organoids, the addition of Wnt3a helps support the proliferation and self-renewal of intestinal stem cells.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eWnt3a can also promote the proliferation and differentiation of neural precursor cells, thereby supporting the maturation and function of neural organoids.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Specifications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eSpecifications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-table-wrap\"\u003e\n \u003ctable class=\"biofargo-table\"\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth style=\"width:25%;\"\u003eParameter\u003c\/th\u003e\n \u003cth style=\"width:75%;\"\u003eSpecification\u003c\/th\u003e\n \u003c\/tr\u003e\n \u003c\/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd\u003eExpression Host\u003c\/td\u003e\n \u003ctd\u003eHEK293 cells\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eSynonyms\u003c\/td\u003e\n \u003ctd\u003eWnt-3a; Wnt 3a; WNT3A; Wnt Surrogate-Fc Fusion\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eProtein Sequence\u003c\/td\u003e\n \u003ctd\u003eAmino acid sequence: Met1–Lys352 of human Wnt3a (UniProt ID: P56704-1) with hFc (IgG1) tag at the C-Terminus\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eMolecular Weight\u003c\/td\u003e\n \u003ctd\u003ePredicted molecular weight is 58.5 kDa\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurity\u003c\/td\u003e\n \u003ctd\u003e\u0026gt;95%, analyzed by SDS-PAGE\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eEndotoxin\u003c\/td\u003e\n \u003ctd\u003e\u0026lt;1 EU\/μg\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003ePurification Method\u003c\/td\u003e\n \u003ctd\u003eChromatographic purification\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eAppearance\u003c\/td\u003e\n \u003ctd\u003eWhite lyophilized powder\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003ctr\u003e\n \u003ctd\u003eActivity\u003c\/td\u003e\n \u003ctd\u003eRefer to COA for details\u003c\/td\u003e\n \u003c\/tr\u003e\n \u003c\/tbody\u003e\n \u003c\/table\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Features --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eFeatures\u003c\/h2\u003e\n \u003cul class=\"biofargo-checklist\"\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHEK293-Expressed Human Wnt3a-Fc Fusion Protein\u003c\/strong\u003e\n \u003cp\u003eRecombinant human Wnt3a corresponding to Met1–Lys352 fused with a C-terminal human IgG1 Fc tag, expressed in HEK293 cells with a predicted molecular weight of 58.5 kDa.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eHigh Purity Chromatographic Preparation\u003c\/strong\u003e\n \u003cp\u003ePurity \u0026gt;95% confirmed by SDS-PAGE following chromatographic purification.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eControlled Endotoxin Level\u003c\/strong\u003e\n \u003cp\u003eEndotoxin level \u0026lt;1 EU\/μg suitable for in vitro cell culture and signaling studies.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003cli\u003e\n \u003cspan class=\"biofargo-check\"\u003e✔\u003c\/span\u003e\n \u003cstrong\u003eDefined Lyophilized Protein Format\u003c\/strong\u003e\n \u003cp\u003eSupplied as a white lyophilized powder with verified electrophoretic identity and consistent protein quality.\u003c\/p\u003e\n \u003c\/li\u003e\n \u003c\/ul\u003e\n \u003c\/div\u003e\n\n \u003c!-- Applications --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eApplications\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-grid\"\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eWnt\/β-Catenin Signaling Research\u003c\/h4\u003e\n \u003cp\u003eActivates the canonical Wnt signaling pathway involved in embryonic development, cell proliferation, differentiation, and polarity regulation.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eIntestinal Organoid Culture\u003c\/h4\u003e\n \u003cp\u003eSupports proliferation and self-renewal of intestinal stem cells during intestinal organoid culture.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eNeural Organoid Development\u003c\/h4\u003e\n \u003cp\u003ePromotes proliferation and differentiation of neural precursor cells, facilitating neural organoid maturation and functional studies.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003cdiv class=\"biofargo-app-card\"\u003e\n \u003ch4\u003eStem Cell Culture Systems\u003c\/h4\u003e\n \u003cp\u003eUsed in stem cell culture environments including MSC and iPSC research models.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Storage --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eStorage\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0;\"\u003eStore at -20 ℃\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Instructions --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eInstructions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0 0 10px 0;\"\u003eCentrifuge before reopening the tube. Dissolve the lyophilized protein in distilled water. It is recommended to reconstitute the concentration to greater than 100 μg \/mL.\u003c\/p\u003e\n \u003cp style=\"margin:0;\"\u003eAfter reconstitution, the protein can be stored at -80℃ for 3-6 months and at 2-8℃ for 2-7 days. For optimal storage, aliquot the protein and minimize freeze-thaw cycles.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Precautions --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003ePrecautions\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-card\"\u003e\n \u003cp style=\"margin:0;\"\u003eThis product is only suitable for in vitro cell culture and cannot be used directly in clinical treatment.\u003c\/p\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n \u003c!-- Documents --\u003e\n \u003cdiv class=\"biofargo-section\"\u003e\n \u003ch2 class=\"biofargo-h2\"\u003eDocuments\u003c\/h2\u003e\n \u003cdiv class=\"biofargo-docs\"\u003e\n \u003ca class=\"biofargo-btn primary\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Data_Sheet-Recombinant_human_Wnt3a_protein.pdf?v=1772766572\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-783 Data Sheet\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SDS-Recombinant_Human_Wnt3a_Protein.pdf?v=1772766572\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-783 SDS\u003c\/a\u003e\n \u003ca class=\"biofargo-btn outline\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/COA-Pr2408014-TL-783-0050.pdf?v=1772766572\" target=\"_blank\" rel=\"noopener\"\u003e📄 TL-783 COA\u003c\/a\u003e\n \u003c\/div\u003e\n \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"T\u0026L","offers":[{"title":"50μg","offer_id":51380918583477,"sku":"TL-783-0050","price":220.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/IMG-TL-783-0050.png?v=1772766498"},{"product_id":"recombinant-human-il-4","title":"Recombinant Human IL-4","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eIL-4 (Interleukin-4) is a cytokine primarily secreted by Th2 cells, mast cells, and basophils. It functions by binding to receptor complexes such as IL-4Rα\/γc or IL-4Rα\/IL-13Rα1, activating the JAK-STAT6 signaling pathway to regulate immune responses, cell proliferation, and differentiation. IL-4 modulates immune cell differentiation and function by promoting Th2 cell polarization and is commonly used in in vitro B cell culture systems. In organoid cultures, IL-4 acts synergistically with IL-13 to drive goblet cell differentiation and modulate the immune microenvironment in intestinal organoids. Additionally, IL-4 can suppress neuronal differentiation and promote the generation of astrocytes.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY02201\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured in a cell proliferation assay using TF-1 cells, The ED50 for this effect is ≤ 0.2 ng\/mL, or responding to a specific bioactivity of ＞1x 107 units\/mg.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP05112\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eInterleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e15 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eHis25-Ser153\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at 2°C to 8°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInfluences B cell maturation and antibody class switching.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eDrives Th2 differentiation and suppresses Th1 responses.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eMainly used in immune cell polarization models.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates differentiation programs and phenotypic stability.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human IL-4 (Cat. No. Y02201) SDS-PAGE under reducing (R) condition. The gel was stained with Y02201 SDS-PAGE.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y02201_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human IL-4 (Cat. No. Y02201) SDS-PAGE under reducing (R) condition. The gel was stained with Y02201 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Y02201 stimulates proliferation of TF-1 cells. The ED50 for this effect is ≤0.2 ng\/mL.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y02201_2.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Y02201 stimulates proliferation of TF-1 cells. The ED50 for this effect is ≤0.2 ng\/mL.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Highly consistent bioactivity between different production batches of Recombinant Human IL-4 (Cat. No. Y02201)\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y02201_3.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 3: Highly consistent bioactivity between different production batches of Recombinant Human IL-4 (Cat. No. Y02201)\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250418-Y02201-Recombinant%20Human%20IL-4-10ug%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284496183477,"sku":"Y02201-50ug","price":310.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284496216245,"sku":"Y02201-1mg","price":1836.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y02201.jpg?v=1771997633"},{"product_id":"recombinant-human-fgf-10","title":"Recombinant Human FGF-9","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eFGF-9 (Fibroblast Growth Factor 9), a member of the FGF family, is a secreted protein that lacks a traditional signal peptide sequence and relies on a non-classical pathway for its secretion. It primarily activates downstream signaling pathways (such as MAPK and PI3K-AKT) by binding to FGFR1, FGFR2, and FGFR3 (IIIc isoform). FGF-9 is involved in neural development, angiogenesis, skeletal formation, and the progression of certain cancers (e.g., prostate cancer and glioma). This factor promotes cell proliferation and differentiation, enhances the proliferation of mesenchymal stem cells (MSCs), and maintains their multipotent differentiation potential. Additionally, FGF-9 participates in bone and cartilage regeneration and supports the survival and expansion of neural precursor cells. When combined with other growth factors, it can help maintain stemness and optimize culture systems for specific cell types.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY01001\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 1-3 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP31371\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eFibroblast Growth Factor 9; FGF-9; Glia-Activating Factor; GAF; Heparin-Binding Growth Factor 9; HBGF-9; FGF9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e23.2 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003ePro3-Ser208\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports proliferation and differentiation of neural stem cells, mesenchymal stem cells, and organoid development.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates cell proliferation, survival, tissue morphogenesis, and developmental signaling, especially in neural and musculoskeletal tissues.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human FGF9 (Cat. No. Y01001) SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y01001 SDS-PAGE.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y01001_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human FGF9 (Cat. No. Y01001) SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y01001 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human FGF9 (Cat. No. Y01001) stimulates proliferation of NIH3T3 cells. The ED50 for this effect is 1-3 ng\/mL. The bioactivity of Y01001 was higher than the other competing product.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y01001_2.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Recombinant Human FGF9 (Cat. No. Y01001) stimulates proliferation of NIH3T3 cells. The ED50 for this effect is 1-3 ng\/mL. The bioactivity of Y01001 was higher than the other competing product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20251021-Y01001-Recombinant%20Human%20FGF9-10%CE%BCg%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284499591349,"sku":"Y01001-50ug","price":336.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284499624117,"sku":"Y01001-1mg","price":2442.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y01001.jpg?v=1771997864"},{"product_id":"recombinant-human-fgf-11","title":"Recombinant Human FGF-10","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eFGF-10 (Fibroblast Growth Factor 10), a member of the FGF family, is a secreted protein that is highly homologous to FGF-7 (KGF) and functions by binding to the FGFR2b receptor. It is primarily involved in epithelial-mesenchymal interactions, regulating embryonic development, tissue repair, and organ formation (such as in the lungs, skin, and prostate). FGF-10 promotes the proliferation of epithelial cells (e.g., keratinocytes, alveolar epithelial cells, and mammary epithelial cells) and certain mesenchymal stem cells (MSCs). In synergy with the Wnt signaling pathway, it is used for the long-term culture of organoids, such as those derived from the intestine and lungs.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY01121H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured by its ability to induce IL-11 secretion by Saos-2 human osteosarcoma cells. The ED50 for this effect is ≤1 ug\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccssion\u003c\/td\u003e\n\u003ctd\u003eO15520\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eFibroblast growth factor 10; FGF-10; Keratinocyte growth factor 2; FGF10; KGF-2; KGF2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eE. coli\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e19.3kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eGln38-Ser208\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnhances proliferation and differentiation of epithelial stem cells and organoids.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eKey regulator of epithelial morphogenesis and tissue regeneration.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250401-Y01121H-Recombinant%20Human%20FGF10%20(E.coli-expressed)%20-%2010ug%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"10ug","offer_id":52402226397365,"sku":"Y01121H-10ug","price":75.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":52284499656885,"sku":"Y01121H-50ug","price":264.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284499689653,"sku":"Y01121H-1mg","price":2442.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y01121H.jpg?v=1771997877"},{"product_id":"recombinant-human-tgf-β1","title":"Recombinant Human TGF-β1","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eTGF-β1 (Transforming Growth Factor-β1) is a multifunctional cytokine belonging to the TGF-β superfamily. It inhibits the growth of most epithelial, endothelial, and hematopoietic cells by inducing cell cycle arrest in the G1 phase. In stem cell culture, TGF-β1 can direct the differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, or adipocytes. In organoid culture systems, it regulates extracellular matrix (ECM) formation and influences tissue organization. Additionally, TGF-β1 exhibits immunomodulatory effects by suppressing the activation of T cells, B cells, NK cells, and macrophages, thereby reducing inflammatory responses. In co-culture systems—such as those involving immune and tumor cells—TGF-β1 can help mimic an immune-suppressive microenvironment.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY04201N\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured in a cell inhibition assay using TF-1 cells at IL4 presence. The ED50 for this effect is ≤0.1ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP01137\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eTransforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e12.8 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eAla279-Ser390\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003e0.085% TFA, 30% ACN, 5% Mannitol, pH 2.5.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in 4mM HCL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates hematopoietic stem cell quiescence and lineage balance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStrong immunosuppressive factor, modulating Tregs and inhibiting effector T cells.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eMaintains stem cell quiescence and guides differentiation; used in organoid cultures.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates proliferation, apoptosis, ECM production, and EMT.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human TGF-β1 (Cat. No. Y04201N) SDS-PAGE under reducing (R) \u0026amp; Non-reducing condition. The gel was stained with Y04201.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y04201N_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human TGF-β1 (Cat. No. Y04201N) SDS-PAGE under reducing (R) \u0026amp; Non-reducing condition. The gel was stained with Y04201.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Measured in a cell inhibition assay using TF-1 cells at IL-4 presence. The ED50 for this effect is ≤0.1 ng\/mL. The bioactivity of Y04201N was higher than other competing products.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y04201N_2.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Measured in a cell inhibition assay using TF-1 cells at IL-4 presence. The ED50 for this effect is ≤0.1 ng\/mL. The bioactivity of Y04201N was higher than other competing products.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20240806-Y04201N-Recombinant%20Human%20TGF%CE%B21-1.0mg-PH2.5%20-%20%E8%8B%B1%E6%96%87.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284499787957,"sku":"Y04201N-50ug","price":431.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284499820725,"sku":"Y04201N-1mg","price":3048.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y04201N.jpg?v=1771997902"},{"product_id":"recombinant-human-vegf165-1","title":"Recombinant Human VEGF165","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eVEGF165 (Vascular Endothelial Growth Factor 165), one of the major isoforms of VEGF-A, functions as a disulfide-linked homodimer and plays a critical role in angiogenesis and cell culture. It activates the VEGFR2\/PI3K\/AKT signaling pathway to inhibit apoptosis and is commonly used to sustain the proliferative capacity of human umbilical vein endothelial cells (HUVECs) and microvascular endothelial cells in vitro. In Matrigel-based tube formation assays, VEGF165 stimulates endothelial cells to form tubular structures, thereby mimicking the process of angiogenesis. In stem cell differentiation systems, it can induce commitment to endothelial cell lineages or support the development of vascular-like structures.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY04701\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured in a cell proliferation assay using HUVEC human umbilicveinendothelial cells. The ED50 for this effect is 0.2-5 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP15692\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eVascular Endothelial Growth Factor Isoform 165; VEGF165\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e19.1kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eAla27-Arg191\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports hematopoietic stem cell niche and endothelial-hematopoietic interactions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnhances immune cell migration via vascular modulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eWidely used to induce vascularization and endothelial differentiation in stem cell\/organoid systems.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePotent regulator of angiogenesis, vascular permeability, and endothelial survival.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human VEGF165 (Cat. No. Y04701) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y04701 SDS-PAGE.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y04701_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human VEGF165 (Cat. No. Y04701) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y04701 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human VEGF165 (Cat. No. Y04701) stimulates proliferation of HUVEC human umbilicvein endothelial cells. The ED50 for this effect is 0.2-10 ng\/mL. Y04701 was higher than the other competing product.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y04701_2.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Recombinant Human VEGF165 (Cat. No. Y04701) stimulates proliferation of HUVEC human umbilicvein endothelial cells. The ED50 for this effect is 0.2-10 ng\/mL. Y04701 was higher than the other competing product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250609-Y04701-Recombinant%20Human%20VEGF165-10%CE%BCg-%E5%85%A8%E8%8B%B1%E7%89%88..pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"display-search-keyword\" style=\"display:none\"\u003egmp-tl612-50\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"10ug","offer_id":52402235015349,"sku":"Y04701-10ug","price":94.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":52284501852341,"sku":"Y04701-50ug","price":330.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284501885109,"sku":"Y04701-1mg","price":2442.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y04701.jpg?v=1771997967"},{"product_id":"recombinant-human-pdgf-bb","title":"Recombinant Human PDGF-BB","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003ePDGF-BB (Platelet-Derived Growth Factor-BB) is an important growth factor belonging to the platelet-derived growth factor (PDGF) family. It consists of two identical B chains linked by disulfide bonds to form a homodimer and is one of the most biologically potent isoforms in the PDGF family. PDGF-BB activates PDGF receptors (PDGFR-α and PDGFR-β) on the cell membrane, triggering downstream signaling pathways that promote the proliferation of various cell types—particularly fibroblasts, smooth muscle cells, glial cells, and mesenchymal stem cells. Additionally, in processes such as wound healing, angiogenesis, and tissue regeneration, PDGF-BB acts as a chemoattractant, guiding cells such as fibroblasts and pericytes to sites of injury to facilitate tissue repair. It also contributes to the stabilization of newly formed blood vessels and works synergistically with VEGF to promote vascular formation.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY03411\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eThe ED50 for this effect is ≤10 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccssion\u003c\/td\u003e\n\u003ctd\u003eP01127\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003ePDGFBB; PDGF-BB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e12.2 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eSer82-Thr190\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003eLyophilized from a 0.22 μm filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePromotes MSC proliferation and vascular support in organoid\/engineered tissues.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates proliferation, migration, and survival of mesenchymal and vascular cells.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human PDGF-BB (Cat. No. Y03411) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03411 SDS-PAGE.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03411_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human PDGF-BB (Cat. No. Y03411) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03411 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250702-Y03411-Recombinant%20Human%20PDGF-BB(CHO-expressed)-10ug%20-%20%E5%85%A8%E8%8B%B1%E7%89%88..pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284501983413,"sku":"Y03411-50ug","price":408.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284502016181,"sku":"Y03411-1mg","price":2456.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y03411.jpg?v=1771997993"},{"product_id":"recombinant-human-noggin","title":"Recombinant Human Noggin","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eNoggin, a secreted protein belonging to the TGF-β superfamily, functions as an endogenous antagonist of bone morphogenetic proteins (BMPs) and plays a key regulatory role in embryonic development, particularly in neural patterning and bone formation. By inhibiting BMP signaling—especially that of BMP4, which normally suppresses neural differentiation—Noggin promotes the differentiation of stem cells (such as embryonic stem cells or induced pluripotent stem cells) into neural precursor cells or neurons. It is therefore commonly used in neural differentiation media for stem cells. Under certain culture conditions, Noggin can also act synergistically with other factors (e.g., FGF2, TGF-β) to help maintain stem cell self-renewal and prevent spontaneous differentiation. Additionally, Noggin is frequently employed in cerebral or neural organoid culture systems to facilitate the formation of neuroepithelial structures.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY03301\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eDetermined by its abitity to inhibit 5.0 ng\/mL of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 2.0-3.0 ng\/mL of Noggin.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eQ13253\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eNoggin; NOG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e23 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eGln28-Cys232\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInhibits BMP signaling to maintain pluripotency and direct differentiation in stem cell cultures.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates morphogenesis and differentiation by antagonizing BMP pathways.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human Noggin (Cat. No. Y03301) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03301 SDS-PAGE.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03301_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human Noggin (Cat. No. Y03301) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03301 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Measured by its ability to inhibit 5.0 ng\/mL of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrocenic cells. The bioactivity of Recombinant Human Noggin (Cat. No.Y03301) is equivalent to competitor.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03301_2.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Measured by its ability to inhibit 5.0 ng\/mL of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrocenic cells. The bioactivity of Recombinant Human Noggin (Cat. No.Y03301) is equivalent to competitor.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Highly consistent bioactivity between different production batches of Recombinant Human Noggin (Cat. No. Y03301).\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03301_3.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 3: Highly consistent bioactivity between different production batches of Recombinant Human Noggin (Cat. No. Y03301).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20240619-Y03301-Recombinant%20Human%20Noggin-10ug%20-%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284504932533,"sku":"Y03301-50ug","price":192.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284504965301,"sku":"Y03301-1mg","price":1620.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y03301_Recombinant_Human_Noggin.jpg?v=1771998058"},{"product_id":"recombinant-human-r-spondin-1","title":"Recombinant Human R-Spondin-1","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eR-Spondin-1 (RSPO1) is a secreted protein belonging to the R-Spondin family and plays a key regulatory role in the Wnt\/β-catenin signaling pathway. By binding to Wnt receptors LRP5\/6 and transmembrane proteins LGR4\/5\/6, RSPO1 inhibits negative regulators of the Wnt pathway and reduces the degradation of Wnt receptors, thereby significantly enhancing Wnt\/β-catenin signaling activity. Through potentiation of Wnt signaling, RSPO1 promotes cell proliferation, stemness maintenance, and tissue regeneration, making it particularly valuable in stem cell culture. In 3D organoid culture systems, RSPO1—when combined with factors such as EGF and Noggin—significantly improves organoid formation efficiency and long-term viability. In stem cell cultures, its use together with Wnt3a supports self-renewal and suppresses differentiation. In summary, R-Spondin-1 is a critical factor in stem cell and organoid culture systems. By modulating the Wnt signaling pathway, it facilitates cell proliferation and maintenance of stemness, and is widely applied in regenerative medicine and disease modeling research.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY03501\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured by its ability to induce Topflash reporter bioactivity in CHO cells in the presence of 50 ng\/mL Wnt3a. The expected ED50 is \u0026lt;1.0 μg\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eQ2MKA7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eRSPO1; R-spondin1; RP11-566C13.1; CRISTIN3; FLJ40906; RSPO Rspo1; R-spondin; Rspondin; RP23-325M14.2; Roof\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e26.7 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eSer21-Ala263\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10 μg \/ 50 μg \/ 1 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%, ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expected biological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePotent activator of Wnt signaling to expand intestinal and organoid stem cells.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEnhances Wnt\/β-catenin-mediated proliferation and stem cell maintenance. and stem cell maintenance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human R-Spondin-1 (Cat. No. Y03501) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03501 SDS-PAGE.\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/1_36651fda-ed0c-4484-87ba-ac78d7b9cbb2.jpg?v=1779779365\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human R-Spondin-1 (Cat. No. Y03501) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03501 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Measured by its ability to induce Topflash reporter bioactivity in CHO cells in the presence of 50 ng\/mL Wnt3a. The expected ED50 is＜1.0 μg\/mL. The bioactivity of Recombinant Human R-Spondin-1(Cat. No. Y03501) was higher than other competing products.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03501_2.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Measured by its ability to induce Topflash reporter bioactivity in CHO cells in the presence of 50 ng\/mL Wnt3a. The expected ED50 is＜1.0 μg\/mL. The bioactivity of Recombinant Human R-Spondin-1(Cat. No. Y03501) was higher than other competing products.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Highly consistent bioactivity between different production batches of Recombinant Human R-Spondin-1 (Cat. No. Y03501).\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03501_3.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 3: Highly consistent bioactivity between different production batches of Recombinant Human R-Spondin-1 (Cat. No. Y03501).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20251021%20-Y03501-%20Recombinant%20Human%20R-Spondin%201-10%CE%BCg%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"10ug","offer_id":52404307689653,"sku":"Y03501-10ug","price":71.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":52284505129141,"sku":"Y03501-50ug","price":246.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284505161909,"sku":"Y03501-1mg","price":2442.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y03501_Recombinant_Human_R-Spondin1.jpg?v=1771998082"},{"product_id":"recombinant-human-scf","title":"Recombinant Human SCF","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eSCF (Stem Cell Factor), also known as KIT ligand or mast cell growth factor, is a glycoprotein that exists in both soluble and membrane-bound forms. It functions by binding to the c-KIT receptor on the cell surface and activating downstream signaling pathways. When used in combination with other cytokines—such as IL-3, IL-6, and FLT3 ligand—SCF promotes the expansion of hematopoietic stem and progenitor cells in vitro. It acts synergistically with EPO to support erythroid progenitor differentiation and with TPO to enhance megakaryopoiesis. In organoid culture systems, SCF helps maintain the activity of intestinal stem cells, mammary stem cells, and other tissue-specific stem cells. The core functions of SCF in cell culture include sustaining stem cell activity, promoting proliferation, and inhibiting apoptosis. It is particularly indispensable in in vitro studies of the hematopoietic system and specific lineage development. Its applications span foundational research, regenerative medicine, and drug development.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY03801\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured in a cell proliferation assay using TF-1 cells. The ED50 for this effect is 5-8 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP21583\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eKit Ligand; Mast Cell Growth Factor; MG\/VAIL F; Stem Cell Factor; SCF; c-Kit ligand; KITLG; MG\/VAIL F; SCF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e18.5 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eGlu 26-Ala 190\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eKey hematopoietic growth factor, supports HSC proliferation and survival.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eEssential for hematopoietic stem cell maintenance and expansion in vitro.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eRegulates stem\/progenitor cell survival, proliferation, and adhesion via c-Kit signaling.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human SCF (Cat. No. Y03801) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03801 SDS-PAGE.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03801_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Recombinant Human SCF (Cat. No. Y03801) SDS-PAGE under reducing (R) \u0026amp; Non-reducing conditions. The gel was stained with Y03801 SDS-PAGE.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Recombinant Human SCF (Cat. No. Y03801) stimulates proliferation of TF-1 cells. The ED50 for this effect is 5-8 ng\/mL. The bioactivity of Y03801 was higher than other competing products.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03801_2.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 2: Recombinant Human SCF (Cat. No. Y03801) stimulates proliferation of TF-1 cells. The ED50 for this effect is 5-8 ng\/mL. The bioactivity of Y03801 was higher than other competing products.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y03801_3.jpg\"\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250923%20-Y03801-Recombinant%20Human%20SCF-10%CE%BCg%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284505358517,"sku":"Y03801-50ug","price":238.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284505391285,"sku":"Y03801-1mg","price":2064.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y03801.jpg?v=1771998095"},{"product_id":"recombinant-human-igf-2","title":"Recombinant Human IGF-2","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eIGF-2 (Insulin-like Growth Factor 2) is an important single-chain polypeptide growth factor composed of 67 amino acids with a molecular weight of approximately 7.5 kDa. It shares structural similarity with insulin and IGF-1 and belongs to the insulin-like growth factor family. In vivo, IGF-2 often binds to IGF-binding proteins (IGFBPs), which regulate its stability and activity. IGF-2 stimulates DNA synthesis and mitosis in various cell types, such as fibroblasts, muscle cells, and neural cells. It is commonly used in stem cell culture—including embryonic stem cells and mesenchymal stem cells—to sustain proliferative capacity. Under specific conditions and in combination with other factors, it can induce differentiation into muscle, cartilage, or neural cells. Additionally, IGF-2 plays regulatory roles in embryonic development and tumor cell growth.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY12441H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is ≤50 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP01344.1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eHEK293\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e7.5kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eAla25-Glu91\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003eLyophilized from a 0.22 μm filtered solution containing TFA, ACN, 5% Trehalose.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in 4 mM HCl.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eModulates fetal hematopoiesis and progenitor expansion.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eMaintains stem cell proliferation and supports organoid growth.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eControls cell proliferation, survival, and growth factor signaling.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is ≤50 ng\/mL.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y12441H_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is ≤50 ng\/mL.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250225-Y12441H-Recombinant%20Human%20IGF-II(%20HEK293-expressed)-10ug%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284506079413,"sku":"Y12441H-50ug","price":155.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284506112181,"sku":"Y12441H-1mg","price":1380.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y12441H.jpg?v=1771998182"},{"product_id":"recombinant-human-il-33","title":"Recombinant Human IL-33","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eIL-33 (Interleukin-33) is a cytokine belonging to the IL-1 family and is mainly expressed by epithelial cells, endothelial cells, and fibroblasts. It signals through the ST2 (IL-1RL1) receptor in complex with IL-1RAcP, activating downstream pathways such as NF-κB and MAPK to initiate type 2 immune responses.\nFunctionally, IL-33 acts as an “alarmin” released upon tissue damage, promoting activation of Th2 cells, ILC2s, mast cells, and eosinophils, and inducing the production of IL-5 and IL-13. In *in vitro* cell and organoid models, IL-33 is commonly used to simulate tissue injury–associated inflammation and type 2 immune microenvironments, particularly in studies of allergy, asthma, and epithelial–immune interactions.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY12821H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤100 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured by its ability to induce IL-8 secretion by HUVEC human umbilic vein endothelial cells. The ED50 for this effect is ≤1.0 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eNP_001186569.1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eE. coli\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eSer112-Thr270\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003eLyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at-20°C to-80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInfluences activation of myeloid and lymphoid immune cells.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eActs as an “alarmin” initiating type 2 immune responses.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eMediates stress and tissue damage signaling.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250805-Y12821H-Recombinant%20Human%20IL-33%EF%BC%88E.coli-expressed)-10ug-%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284508111029,"sku":"Y12821H-50ug","price":396.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284508143797,"sku":"Y12821H-1mg","price":2988.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y12821H.jpg?v=1771998270"},{"product_id":"recombinant-human-vegf121","title":"Recombinant Human VEGF121","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eVEGF121 is a soluble isoform of VEGF-A that lacks heparin-binding domains. It signals mainly through VEGFR-2 to promote endothelial cell proliferation and migration. VEGF121 is commonly used in vitro to support angiogenesis models and vascularization in organoid and tissue engineering systems.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY12301\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured in a cell proliferation assay using HUVEC human umbilic vein endothelial cells. The ED50 for this effect is ＜10 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eP15692\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAlternative Names\u003c\/td\u003e\n\u003ctd\u003eVascular Endothelial Growth Factor Isoform 121; VEGF121\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e14.1kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eAla27-Arg147\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eFormulation\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePBS, 5% Mannitol and 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSupports hematopoietic niche vascularization indirectly.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eModulates immune cell trafficking via vascular remodeling.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eStem Cell Research\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003ePromotes endothelial differentiation and vascularization in organoids and stem cell cultures.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eStimulates angiogenesis, endothelial proliferation, and survival.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Measured in a cell proliferation assay using HUVEC human umbilic vein endothelial cells. The ED50 for this effect is ＜10 ng\/mL.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y12301_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Measured in a cell proliferation assay using HUVEC human umbilic vein endothelial cells. The ED50 for this effect is ＜10 ng\/mL.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250113-Y12301-Recombinant%20Human%20VEGF121-10ug%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284508242101,"sku":"Y12301-50ug","price":336.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284508274869,"sku":"Y12301-1mg","price":2442.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y12301.jpg?v=1771998294"},{"product_id":"recombinant-human-il-17a","title":"Recombinant Human IL-17A","description":"\u003cstyle\u003e.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}}\u003c\/style\u003e\u003cdiv style=\"font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #333; line-height: 1.6; max-width: 1000px; margin: 0 auto; border: 1px solid #e1e8ed; padding: 30px; border-radius: 10px; background-color: #ffffff;\"\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 0; font-size: 22px;\"\u003eDescription\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fcfcfc; padding: 15px; border-radius: 6px; border: 1px solid #f0f0f0;\"\u003e\u003cp style=\"margin: 0; text-align: justify;\"\u003eIL-17A (Interleukin-17A) is a pro-inflammatory cytokine mainly produced by Th17 cells, as well as γδ T cells and innate lymphoid cells. It signals through the IL-17RA\/IL-17RC receptor complex, activating NF-κB and MAPK pathways to induce inflammatory responses.\nFunctionally, IL-17A promotes chemokine and cytokine production, drives neutrophil recruitment, and plays a key role in mucosal defense against extracellular bacteria and fungi. In in vitro cell and organoid models, IL-17A is commonly used to mimic inflammatory microenvironments and often acts synergistically with TNF-α or IL-22. Dysregulated IL-17A signaling is implicated in autoimmune and chronic inflammatory diseases such as psoriasis and inflammatory bowel disease.\u003c\/p\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"biofargo-table-wrapper\"\u003e\u003ctable class=\"biofargo-spec-table\"\u003e\n\u003cthead\u003e\u003ctr style=\"background-color: #0056b3; color: white;\"\u003e\u003cth style=\"padding: 12px; text-align: left;\" colspan=\"2\"\u003eProduct Details\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eCat. No.\u003c\/td\u003e\n\u003ctd\u003eY06601H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003ePurity\u003c\/td\u003e\n\u003ctd\u003e≥95%, by SDS-PAGE (under reducing (R) \u0026amp; Non-reducing conditions, visualized by Coomassie staining).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd\u003e≤10 EU\/mg by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBioactivity\u003c\/td\u003e\n\u003ctd\u003eMeasured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is＜10 ng\/mL.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eAccession\u003c\/td\u003e\n\u003ctd\u003eQ16552\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSpecies\u003c\/td\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression System\u003c\/td\u003e\n\u003ctd\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eMol. Weight\u003c\/td\u003e\n\u003ctd\u003e15.5 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eExpression Region\u003c\/td\u003e\n\u003ctd\u003eIle20-Ala155\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eTag Info\u003c\/td\u003e\n\u003ctd\u003eTag free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eForm\u003c\/td\u003e\n\u003ctd\u003eLyophilized\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003eLyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol, 0.01% Tween 80, pH7.4.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eSize\u003c\/td\u003e\n\u003ctd\u003e10μg\/50μg\/1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eLead Time\u003c\/td\u003e\n\u003ctd\u003eProducts are in stock, but custom products may require further consultation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd\u003eIt is recommended to redissolve in sterile deionized water.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with blue ice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold; background-color: #f8f9fa;\" width=\"26%\"\u003eStorage \u0026amp; Stability\u003c\/td\u003e\n\u003ctd\u003e36 months at -20°C to-80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eFeatures\u003c\/h2\u003e\n\u003cul style=\"list-style-type: none; padding: 0;\"\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Purity:\u003c\/strong\u003e This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eHigh Biological Activity:\u003c\/strong\u003e Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eBatch Consistency:\u003c\/strong\u003e Manufactured under strict production and quality control protocols to ensure highconsistency between batches.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 15px; padding-left: 30px; position: relative;\"\u003e\n\u003cspan style=\"position: absolute; left: 0; color: #0056b3; font-weight: bold;\"\u003e✔\u003c\/span\u003e \u003cstrong\u003eAnimal-Free:\u003c\/strong\u003e Produced without the use of animal-derived components, meeting animal-free requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eApplications\u003c\/h2\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 20px;\"\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eHematology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInvolved in inflammation-related hematopoietic regulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eImmunology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eSignature Th17 cytokine driving chronic inflammation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"border: 1px solid #e1e8ed; padding: 15px; border-radius: 8px;\"\u003e\n\u003ch4 style=\"margin-top: 0; color: #333;\"\u003eCell Biology\u003c\/h4\u003e\n\u003cp style=\"font-size: 14px; margin-bottom: 0;\"\u003eInduces expression of inflammation-related genes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eData Figures\u003c\/h2\u003e\n\u003cdiv style=\"text-align: center; margin-top: 20px; border: 1px solid #eee; padding: 15px; border-radius: 8px;\"\u003e\n\u003cimg style=\"max-width: 100%; height: auto;\" alt=\"Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is＜10 ng\/mL.\" src=\"https:\/\/files.biofargo.com\/eastmabbio\/product-detail-images\/Y06601H_1.jpg\"\u003e\u003cp style=\"font-size: 13px; color: #888; margin-top: 10px;\"\u003eFigure 1: Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is＜10 ng\/mL.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eInstructions for Use\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px;\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003ePrepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003eDo not mix with other similar products to avoid cross-reactivity and potential interference.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eCautions\u003c\/h2\u003e\n\u003cdiv style=\"background-color: #fff5f5; padding: 15px; color: #852d2d; font-size: 14px;\"\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Research Use Only:\u003c\/strong\u003e This product is not suitable for clinical diagnostics or therapeutic applications.\u003c\/p\u003e\n\u003cp style=\"margin: 0 0 8px 0;\"\u003e\u003cstrong\u003e• Preservation:\u003c\/strong\u003e Handle according to instructions to preserve its activity and stability.\u003c\/p\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cstrong\u003e• Support:\u003c\/strong\u003e Contact our technical support team if you encounter any issues or questions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2 style=\"color: #0056b3; border-bottom: 2px solid #0056b3; padding-bottom: 8px; margin-top: 30px; font-size: 22px;\"\u003eDocuments\u003c\/h2\u003e\n\u003cdiv style=\"display: flex; gap: 15px; margin-top: 10px; flex-wrap: wrap;\"\u003e\n\u003ca style=\"display: inline-block; padding: 10px 20px; border: 2px solid #0056b3; color: #0056b3; text-decoration: none; border-radius: 5px; font-weight: bold; font-size: 14px;\" href=\"https:\/\/files.biofargo.com\/eastmabbio\/coa\/20250804-Y06601H-Recombinant%20Human%20IL-17A-10%CE%BCg%20-%20%E5%85%A8%E8%8B%B1%E7%89%88.pdf\" target=\"_blank\"\u003e📄 Download COA\u003c\/a\u003e \u003c\/div\u003e\n\u003c\/div\u003e","brand":"EastMabBio","offers":[{"title":"50ug","offer_id":52284508471477,"sku":"Y06601H-50ug","price":300.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":52284508504245,"sku":"Y06601H-1mg","price":2640.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/Y06601H.jpg?v=1771998317"},{"product_id":"sk-o180-c-remote-controlled-smart-destaining-shaker","title":"SK-O180-C Remote-Controlled Smart Destaining Shaker","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eThe SK-O180-C Remote-Controlled Smart Destaining Shaker is an advanced orbital shaker designed for precise and contamination-reduced mixing in molecular biology, microbiology, and biochemical laboratories. Equipped with an integrated wireless module and remote controller, the system allows users to monitor and adjust operating parameters without directly interacting with the shaker, minimizing disturbances to sensitive experimental environments.\u003c\/p\u003e\n\u003cp\u003eThe shaker operates with a 20 mm orbital amplitude and a speed range of 40–200 rpm, providing gentle and uniform agitation suitable for gel destaining, cell culture processes, nucleic acid hybridization, and protein analysis workflows. Real-time speed and timer values are clearly displayed through the LED interface, allowing easy monitoring of experimental conditions.\u003c\/p\u003e\n\u003cp\u003eDesigned for flexibility, the device supports both wireless and wired connections, enabling reliable remote control in different laboratory setups. The remote controller offers more than 10 meters of unobstructed operating distance and features a magnetic back for convenient attachment to metal surfaces. With Type-C fast charging and long battery life, the controller ensures stable and continuous operation during extended experiments.\u003c\/p\u003e\n\u003cp\u003eThe SK-O180-C is powered by a durable brushless DC motor that delivers stable shaking performance with minimal noise and long service life. Safety features including RPM protection help maintain stable operation and protect samples during shaking processes.\u003c\/p\u003e\n\u003cp\u003eWith a compact footprint, a maximum load capacity of 2 kg, and remote-control functionality designed to reduce contamination risk, the SK-O180-C Smart Destaining Shaker provides an efficient solution for controlled mixing in sterile, temperature-sensitive, or enclosed laboratory environments.\u003c\/p\u003e\n\u003ch2\u003eSpecification\u003c\/h2\u003e\n\u003ctable border=\"1\" style=\"border-collapse: collapse; width: 90%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cstrong\u003eParameter\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cstrong\u003eSpecification\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eMotion Type\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eOrbital Shaker\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eAmplitude\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e20 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eSpeed Range\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e40–200 rpm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eSpeed Display\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eLED\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eTimer Display\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eLED\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eTime Settings Range\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e1 min – 99 h 59 min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eData Connector\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eType-C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eMax. Load Capacity (with Platform)\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e2 kg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eMotor Type\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eDC Brushless Motor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eMotor Rating Input\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e16 W\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eMotor Rating Output\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e10 W\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003ePower\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e20 W\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eVoltage\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e100–240 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eFrequency\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e50 \/ 60 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eDimension [W × D × H]\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eMain Unit: 294 × 348 × 130 mm; Remote Control: 190 × 90 × 30 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eWeight\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e3.4 kg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003ePermissible Ambient Temperature\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e5–40 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003ePermissible Ambient Humidity\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e80% RH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center;\"\u003eProtection Class\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eIP21\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eLED Display: Real-time display of speed and time\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDual-mode Connection: Wireless + wired dual support, flexible for different scenarios\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eOver 10 meters of remote control: Unobstructed remote control, reducing interference from opening doors, stabilizing the experimental environment\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMagnetic Design: The remote control can be attached to metal surfaces, easy to access and prevent loss\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eType-C Fast Charging: Long-lasting battery, convenient charging, and durable\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSafety RPM Protection Function\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePollution Reduction: Suitable for sterile, low-temperature, or enclosed space operations\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSafe and Convenient: Reduces human risks in dangerous experiments or repetitive operations\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eCell Culture: Sterile environment cell culture \/ Organoid culture\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMicrobiology Research: Bacteria \/ Yeast fermentation process control\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMolecular Experiments: Nucleic acid hybridization, protein purification\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePharmaceutical Development: High-throughput screening, formulation testing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSpecial Environments: Low temperature \/ Anaerobic \/ Hazardous sample processing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"DLAB","offers":[{"title":"SK-O180-C","offer_id":52332775178421,"sku":"8072210401","price":271.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/files\/SK-O1810-C.jpg?v=1773036490"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0521\/5312\/2997\/collections\/00001_fed10f98-d53d-46f1-b945-bf33f85ffb00.jpg?v=1776327907","url":"https:\/\/biofargo.com\/collections\/organoid-culture.oembed?page=2","provider":"Biofargo","version":"1.0","type":"link"}