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Olpasiran-First In Class-Cholesterol Reducing
Description Olpasiran is a first-in-class, siRNA designed to inhibit LPA mRNA translation in hepatocytes and thereby reduce plasma Lipoprotein(a) or Lp(a) concentration. Product information Targets: Lipoprotein(a); Lipoprotein Synonym: Olpasiran Chemical Name/IUPAC:...
$1,300.00
RMC-0331
Description RMC-0331 is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction. Specification Catalog...
$390.00
PLX-5622
Description PLX-5622 is a highly selective brain-penetrant CSF1R inhibitor (IC50=0.016 µM; Ki=5.9 nM) allowing for extended and specific microglial elimination, preceding and during pathology development. Notice: PLX-5622 also works well...
$50.00
MLN-4924 (Pevonedistat)
Description MLN-4924 (Pevonedistat) is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN-4924 binds to and inhibits NAE, which may result in the...
$80.00
RMC-6236
Description RMC-6236 is a first-in-class, potent, oral RAS-selective tri-complex, RAS(MULTI)(ON) inhibitor with an attractive preclinical profile and is designed to treat cancers caused by multiple RAS variants for which no...
$1,300.00
BDTX-1535
Description BDTX-1535 is an orally bioavailable, brain-penetrating, mutation-selective, EGFR inhibitor with potential antitumor activity.BDTX-1535 is a fourth-generation EGFR inhibitor that overcomes resistance to Osimertinib, the standard of care for EGFR-mutant...
$190.00
BI-2865
Description BI-2865 is a pan-KRAS inhibitor disables oncogenic signalling and tumour growth. BI-2865 blocks nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants,...
$450.00
BMS-906024, Purity: 98.10%
Description: BMS-906024 is an orally active and selective γ-secretase (gamma secretase) inhibitor. BMS-906024 is a potent pan-Notch receptors inhibitor with IC50s of 1.6 nM, 0.7 nM, 3.4 nM, and 2.9...
$500.00
LR white acrylic resins
CAS Number: 94188-59-7 MDL number: MFCD00131541 NACRES: NA.47 1, Properties: biological source: synthetic Quality Level:200 refractive index: n/D 1.4592-1.4610 application(s): hematology, histology shipped in: wet ice storage temp.: 2-8°C 2, Description: Application LR white acrylic...
$91.50
6,7-diketolithocholic acid
Product Details
ITI0518113-1mg
Category
Sterols
Size
1mg
Purity
99%
Molecular Weight
C24H36O5
Molecular Formula
404.54
Appearance
Solid
Synonyms
5ß-cholanic acid-3α-ol-6,7-dione
Storage
-20℃ Freezer
Shelf Life
1 Year
$310.00
Thiostrepton
Description: Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide class. It is derived from several strains of streptomycetes. Typical Properties: Form: white to off-white powder...
$60.00
Blue Dextran 2000
Description: Blue Dextran 2000 is prepared from dextran with a m.w. of ~ 2,000,000. It is soluble in water, and is supplied as a dark blue powder or crystal. Typical Properties: ...
$45.00
Methylcobalamin, C63H91CoN13O14P
Description: Methylcobalamin is a vitamin B12 analog. Typical Properties: Typical Properties: Form: Dark red crystalline or crystalline powder Purity (on dry basis): 98% Min Loss on drying 12% Max...
$295.00
β-Diphosphopyridine nucleotide, C21H27N7O14P2
Description: β-Diphosphopyridine nucleotide consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other one contains an nicotinamide. It is a coenzyme central to metabolism....
$255.00
Adenosine, Adenine-9-β-D-ribofuranoside
Description: Adenosine is one of the four nucleoside building blocks to DNA and RNA. Typical Properties: Typical Properties: Form: White to off-white powder Content (on dry basis): 98.5% Min Adenine:...
$165.00
4-Methylumbellifery β-D-galactopyranoside
Description: 4-Methylumbellifery β-D-galactopyranoside may be used as a fluorescent substrate for β-galactosidase. Typical Properties: Typical Properties: Form: White or off-white power Purity (TLC): 98% Min Product Details: Product Details: ...
$175.00
IPTG: Isopropyl β-D-thiogalactoside C9H18O5S
Description: Isopropyl β-D-thiogalactoside, IPTG, is a molecular biology reagent, and is a molecular mimic of allolactose. When stored as a powder under proper conditions, IPTG is stable for 5 years. Typical...
$50.00
GalNAc: N-Acetyl-D-galactosamine
Description: N-Acetyl-D-galactosamine (GalNAc) is an amino sugar derivative of galactose. In humans it is the terminal carbohydrate forming the antigen of blood group A. Typical Properties: Typical Properties: Form:...
$125.00
Tolyltriazole
Description Tolyltriazole is a heterocyclic organic compound. It is a white to slightly yellowish powder and belongs to the triazole group. Tolyltriazole has similar applications to benzotriazole as a corrosion...
$407.00
Oleylamine
Description Oleylamine (AO V) is organic synthetic intermediates, it is an intermediate of organic synthesis. Oleylamine (AO V) is synthetic raw materials for amine ether products, which is widely used...
$3,120.00
2-ethylhexyl phosphate (mixture of mono- and di-)
Description 2-Ethylhexyl Phosphate is a mixture of mono and di-esters that finds applications as an extractant for the separation of rare earth metals, actinides, and lanthanides in the nuclear industry....
$84.90
GMO (glyceryl monooleate)
Description Glyceryl Monooleate is a clear or light yellow oil that is used as an antifoam in juice processing. It has been used as an emulsifier, a moisturizer, and a...
$2,000.00
Oleamide
Description General description Oleamide is a lipid or a brain fatty acid, that is found in the CSF (cerebrospinal fluid). It is originally obtained from the cerebrospinal fluid of cats,...
$341.00
RMC-7977
Description RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants (a RASMULTI(ON) inhibitor). Preclinically, RMC-7977 demonstrated potent...
$400.00
2-Ethylhexyl alcohol
Description General description This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets...
$478.61
1-Octanol
Description General description 1-Octanol is a saturated fatty alcohol with potential application as a biofuel due to its diesel-like properties. Application 1-Octanol may be used to prepare octanal via aerobic...
$96.20
1,2-Hexanediol
Description General description 1,2-Hexanediol acts as cosurfactant, used for modifying the sodium dodecyl sulfate micelles. Solubility of 1,2-hexanediol in supercritical CO2 has been reported. It has a tendency of self-association to...
$32.20
Oleic acid
Description General description Oleic acid (OA), a non-essential fatty acid, is classified as monounsaturated fatty acid (MUFA) richly present in olive oil. Its quantitative removal from the mixtures of triglyceride and...
$24.97
Stearic acid
Description General description Stearic acid (SA) is a straight chain fatty acid. It forms ordered monolayered Langmuir-Blodgett (LB) films on the surface of germanium. These LB films have been investigated...
$41.50
Adipic acid
Description General description Adipic acid is a straight-chain aliphatic dicarboxylic acid, commonly used in the manufacturing of nylon-6,6 and plasticizers. Conventionally it was manufactured from petrochemicals but in recent days...
$19.90
Sebacic acid
Description General description Sebacic acid is a castor oil-derived dicarboxylic acid. It is widely used to produce polymers, plasticizers, lubricants, and corrosion retardants. It can act as a pH corrector in...
$56.60
Sulfo-ara-F-NMN
Description Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production. In...
$425.00
GSK126 (CAS 1346574-57-9)
Description GSK 126 is a very high affinity and selective EZH2 inhibitor (Ki = 0.5 - 3 nM). Exhibits >150-fold selectivity for EZH2 over EZH1 and >1000-fold selectivity over 20...
$36.00
GSK-LSD1
Description GSK-LSD1, an LSD1 inhibitor, decreases food consumption and body weight while enhancing insulin sensitivity and glycemic regulation in murine obesity models. Additionally, it mitigates non-alcoholic fatty liver disease (NAFLD)...
$115.00
SGX-523
Description A cell-permeable triazolopyridazine compound that acts as a potent, ATP-competitive (Ki = 2.7 & 23 nM using non-phosphorylated and phosphorylated MET kinase domain, respectively), and highly selective inhibitor against...
$25.00
Danirixin
Description Danirixin (GSK1325756) is an orally active, selective CXC chemokine receptor 2 (CXCR2) antagonist with 78-fold lower affinity toward CXCR1 (CXCR2/CXCR1 IC50 = 12.5/977 nM by competitive binding against 0.225...
$50.00
B-Raf inhibitor 1
Description B-Raf inhibitor 1 (Compound 13) is a type IIA Raf inhibitor which bind to the DFG-out conformation with ki of 1 nM,1 nM,and 0.3 nM for B-Raf(WT), B-Raf(V600E) and...
$46.50
Anamorelin
Description Anamorelin is a non-peptidic ghrelin mimetic and growth hormone (GH) secretagogue. It is an orally-active, brain-penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). Anamorelin has been shown...
$35.00
PI-3065
Description PI 3065 is a potent and selective PI 3-kinase p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM). Exhibits >100-fold selectivity over p100α, p100γ and p100β isoforms (IC50...
$45.00
